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Pap test accuracy and severity of squamous intraepithelial lesion

Cobucci, RNO ; Maisonnette, MJAS ; Macêdo, EJS ; Santos Filho, F ; Rodovalho, PEF ; Nóbrega, M ; Gonçalves, AKS

Indian journal of cancer, 2016-01, Vol.53 (1), p.74-76 [Periódico revisado por pares]

India: Wolters Kluwer - Medknow Publications

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Título:
Pap test accuracy and severity of squamous intraepithelial lesion
Autor: Cobucci, RNO ; Maisonnette, MJAS ; Macêdo, EJS ; Santos Filho, F ; Rodovalho, PEF ; Nóbrega, M ; Gonçalves, AKS
Assuntos: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Care and treatment ; Cervical cancer ; Cross-Sectional Studies ; Diagnosis ; Evaluation ; Female ; Humans ; Middle Aged ; Pap test ; Papanicolaou Test - methods ; Squamous cell carcinoma ; Squamous Intraepithelial Lesions of the Cervix - diagnosis ; Squamous Intraepithelial Lesions of the Cervix - pathology ; Young Adult
É parte de: Indian journal of cancer, 2016-01, Vol.53 (1), p.74-76
Descrição: Background: Cytology smears and guided biopsies are the most widely used diagnostic standards for cervical cancer (CC) screening in the developing countries. Aim: To evaluate the performance of conventional cytology in estimating the presence and grade of cervical disease against the reference standard of histopathology. Settings and Design: After primary screening for CC, directed biopsies were performed and compared with histopathology results. Materials and Methods: Papanicolaou (Pap) smears and biopsies from 3194 women in the age group of 14-98 years were included. Cytology results were provided by doctors who performed the cervical biopsies. Statistical Analysis: The accuracy of Pap smear was measured by sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) calculated using the statistical analysis program PSPP 0.7.8. Results: The sensitivity of conventional cytology (Pap smear) for women with low-grade cervical intraepithelial neoplasia or less serious lesions (CIN1-) was 93% and specificity was 73%. The sensitivity and specificity of cytology for women with high-grade cervical intraepithelial neoplasia or cancer (CIN2+) was 64% and 84%, respectively. Conclusion: Cytology is a sufficiently sensitive test for detection of cervical lesions and can be used as a primary testing tool to triage.
Editor: India: Wolters Kluwer - Medknow Publications
Idioma: Inglês

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Pap test accuracy and severity of squamous intraepithelial lesion

Cobucci, RNO ; Maisonnette, MJAS ; Macêdo, EJS ; Santos Filho, F ; Rodovalho, PEF ; Nóbrega, M ; Gonçalves, AKS

India: Wolters Kluwer - Medknow Publications

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