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Effectiveness of antiepileptic therapy in patients with PCDH19 mutations

Lotte, Jan ; Bast, Thomas ; Borusiak, Peter ; Coppola, Antonietta ; Cross, J. Helen ; Dimova, Petia ; Fogarasi, Andras ; Graneß, Irene ; Guerrini, Renzo ; Hjalgrim, Helle ; Keimer, Reinhard ; Korff, Christian M ; Kurlemann, Gerhard ; Leiz, Steffen ; Linder-Lucht, Michaela ; Loddenkemper, Tobias ; Makowski, Christine ; Mühe, Christian ; Nicolai, Joost ; Nikanorova, Marina ; Pellacani, Simona ; Philip, Sunny ; Ruf, Susanne ; Sánchez Fernández, Iván ; Schlachter, Kurt ; Striano, Pasquale ; Sukhudyan, Biayna ; Valcheva, Deyana ; Vermeulen, R. Jeroen ; Weisbrod, Tanja ; Wilken, Bernd ; Wolf, Philipp ; Kluger, Gerhard

Seizure (London, England), 2016-02, Vol.35, p.106-110 [Periódico revisado por pares]

England: Elsevier Ltd

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Título:
Effectiveness of antiepileptic therapy in patients with PCDH19 mutations
Autor: Lotte, Jan ; Bast, Thomas ; Borusiak, Peter ; Coppola, Antonietta ; Cross, J. Helen ; Dimova, Petia ; Fogarasi, Andras ; Graneß, Irene ; Guerrini, Renzo ; Hjalgrim, Helle ; Keimer, Reinhard ; Korff, Christian M ; Kurlemann, Gerhard ; Leiz, Steffen ; Linder-Lucht, Michaela ; Loddenkemper, Tobias ; Makowski, Christine ; Mühe, Christian ; Nicolai, Joost ; Nikanorova, Marina ; Pellacani, Simona ; Philip, Sunny ; Ruf, Susanne ; Sánchez Fernández, Iván ; Schlachter, Kurt ; Striano, Pasquale ; Sukhudyan, Biayna ; Valcheva, Deyana ; Vermeulen, R. Jeroen ; Weisbrod, Tanja ; Wilken, Bernd ; Wolf, Philipp ; Kluger, Gerhard
Assuntos: Adolescent ; Adult ; Age Factors ; Anticonvulsants - therapeutic use ; Antiepileptic drugs ; Cadherins - genetics ; Child ; Child, Preschool ; Epilepsy ; Epilepsy - drug therapy ; Epilepsy - genetics ; Female ; Follow-Up Studies ; Humans ; Long-term effectiveness ; Mutation - genetics ; Neurology ; PCDH19 mutation ; Pharmacogenetics ; Red Cross ; Retrospective Studies ; Surveys and Questionnaires ; Treatment ; Treatment Outcome ; Young Adult
É parte de: Seizure (London, England), 2016-02, Vol.35, p.106-110
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Highlights • Bromide and clobazam turned out to be the most effective drugs after 3 and 12 months. • Three-quarters of our patients were seizure-free for at least 3 months, half of them for one year and two even for over 10 years. • Assessing the effectiveness of drugs is difficult because an age-dependent and spontaneous seizure remission must be considered.
Editor: England: Elsevier Ltd
Idioma: Inglês

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Effectiveness of antiepileptic therapy in patients with PCDH19 mutations

England: Elsevier Ltd

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