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Dietary intake of saturated fat by food source and incident cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis

DE OLIVEIRA OTTO, Marcia C ; MOZAFFARIAN, Dariush ; KROMHOUT, Daan ; BERTONI, Alain G ; SIBLEY, Christopher T ; JACOBS, David R ; NETTLETON, Jennifer A

The American journal of clinical nutrition, 2012-08, Vol.96 (2), p.397-404 [Periódico revisado por pares]

Bethesda, MD: American Society for Nutrition

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Título:
Dietary intake of saturated fat by food source and incident cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis
Autor: DE OLIVEIRA OTTO, Marcia C ; MOZAFFARIAN, Dariush ; KROMHOUT, Daan ; BERTONI, Alain G ; SIBLEY, Christopher T ; JACOBS, David R ; NETTLETON, Jennifer A
Assuntos: Aged ; Aged, 80 and over ; Animals ; Atherosclerosis ; Atherosclerosis - epidemiology ; Atherosclerosis - etiology ; Biological and medical sciences ; blood-pressure ; Cardiovascular disease ; Cattle ; cholesterol ; consumption ; coronary-heart-disease ; Correlation analysis ; Dairy Products - analysis ; Diet ; Dietary Fats - administration & dosage ; Fatty Acids - administration & dosage ; Feeding Behavior ; Feeding. Feeding behavior ; Female ; Follow-Up Studies ; Fundamental and applied biological sciences. Psychology ; Humans ; hypertension ; Incidence ; Life Style ; Male ; Meat - analysis ; mesa ; metaanalysis ; Middle Aged ; Nutrition Assessment ; Nutrition research ; Oils & fats ; patterns ; Prospective Studies ; Regression Analysis ; Risk Factors ; Surveys and Questionnaires ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; womens health
É parte de: The American journal of clinical nutrition, 2012-08, Vol.96 (2), p.397-404
Descrição: Although dietary recommendations have focused on restricting saturated fat (SF) consumption to reduce cardiovascular disease (CVD) risk, evidence from prospective studies has not supported a strong link between total SF intake and CVD events. An understanding of whether food sources of SF influence these relations may provide new insights. We investigated the association of SF consumption from different food sources and the incidence of CVD events in a multiethnic population. Participants who were 45-84 y old at baseline (n = 5209) were followed from 2000 to 2010. Diet was assessed by using a 120-item food-frequency questionnaire. CVD incidence (316 cases) was assessed during follow-up visits. After adjustment for demographics, lifestyle, and dietary confounders, a higher intake of dairy SF was associated with lower CVD risk [HR (95% CI) for +5 g/d and +5% of energy from dairy SF: 0.79 (0.68, 0.92) and 0.62 (0.47, 0.82), respectively]. In contrast, a higher intake of meat SF was associated with greater CVD risk [HR (95% CI) for +5 g/d and a +5% of energy from meat SF: 1.26 (1.02, 1.54) and 1.48 (0.98, 2.23), respectively]. The substitution of 2% of energy from meat SF with energy from dairy SF was associated with a 25% lower CVD risk [HR (95% CI): 0.75 (0.63, 0.91)]. No associations were observed between plant or butter SF and CVD risk, but ranges of intakes were narrow. Associations of SF with health may depend on food-specific fatty acids or other nutrient constituents in foods that contain SF, in addition to SF.
Editor: Bethesda, MD: American Society for Nutrition
Idioma: Inglês

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Dietary intake of saturated fat by food source and incident cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis

DE OLIVEIRA OTTO, Marcia C ; MOZAFFARIAN, Dariush ; KROMHOUT, Daan ; BERTONI, Alain G ; SIBLEY, Christopher T ; JACOBS, David R ; NETTLETON, Jennifer A

Bethesda, MD: American Society for Nutrition

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