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3d imaging of the upper airways of Treacher Collins syndrome subjects preliminary report

Alexandre de Almeida Ribeiro Michele Alves Garcia; Cristiano Tonello; Ivy Kiemle Trindade Suedam; Simpósio Internacional de Fissuras Orofaciais e Anomalias Relacionadas (5. 2017 Bauru)

Anais Bauru:Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, 2017

Bauru Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo 2017

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  • Título:
    3d imaging of the upper airways of Treacher Collins syndrome subjects preliminary report
  • Autor: Alexandre de Almeida Ribeiro
  • Michele Alves Garcia; Cristiano Tonello; Ivy Kiemle Trindade Suedam; Simpósio Internacional de Fissuras Orofaciais e Anomalias Relacionadas (5. 2017 Bauru)
  • Assuntos: ANORMALIDADES CRANIOFACIAIS; TERCEIRA DIMENSÃO; SISTEMA RESPIRATÓRIO
  • É parte de: Anais Bauru:Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo, 2017
  • Notas: Disponível em: http://hrac.usp.br/wp-content/uploads/2018/11/ebook_anais_v_simposio_internacional_pg_hrac_2017.pdf
  • Notas Locais: MProd Digital
  • Descrição: Objective: Treacher Collins Syndrome (TCS), a rare congenital craniofacial syndrome, is characterized by mandibular and zygoma hypoplasia. These craniofacial defects may reduce upper airway dimensions, impair ventilation and lead to obstructive sleep apnea. Considering that narrowing of pharyngeal dimensions may constitute a risk factor for obstructive sleep apnea, this preliminary report aimed at presenting a case series of TCS patients with severe skeletal and airway dysmorphologies. Methods: Five adults with TCS who underwent cone beam computed tomography for craniofacial surgery planning, were prospectively assessed. The pharyngeal volume and the minimum pharyngeal cross-sectional area were assessed using the Dolphin Imaging 11.7 software. A control group (n=5) of adults with skeletal class II malocclusion, without syndromes, was also assessed. Results: Volume mean values (±sd) observed for the TCS group and CON group corresponded to 13.7±6,6 cm3 and 25.6±9.1 cm3. Minimum pharyngeal cross-sectional area means values (±sd) were 56,0±20,2 mm2 and 114.7±35.0 mm2. Conclusion: In this report, pharyngeal volumes and minimal cross-sectional areas of TCS group were reduced in relation to that of individuals with skeletal class II malocclusion. Reduction of the minimum cross-sectional area in these cases is of special clinical interest. In face of these preliminary findings, it can be speculated that this population may be at a greater risk for obstructive sleep apnea due to the reduced pharyngeal dimensions observed. This is in accordance with the clinical respiratory complaints frequently observed. Further polysomnographic studies are still necessary for assessing respiratory profile and obstructive sleep apnea prevalence in this syndromic population.
  • Editor: Bauru Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo
  • Data de criação/publicação: 2017
  • Formato: p. 12.
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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