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High-Density Lipoprotein Cholesterol Level Relates to Working Memory, Immediate and Delayed Cued Recall in Brazilian Older Adults: The Role of Cognitive Reserve

Ihle, Andreas ; Gouveia, Élvio R ; Gouveia, Bruna R ; Freitas, Duarte L ; Jurema, Jefferson ; Tinôco, Maria A ; Kliegel, Matthias

Dementia and geriatric cognitive disorders, 2017-01, Vol.44 (1-2), p.84-91 [Periódico revisado por pares]

Switzerland: S. Karger AG

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High-Density Lipoprotein Cholesterol Level Relates to Working Memory, Immediate and Delayed Cued Recall in Brazilian Older Adults: The Role of Cognitive Reserve
Autor: Ihle, Andreas ; Gouveia, Élvio R ; Gouveia, Bruna R ; Freitas, Duarte L ; Jurema, Jefferson ; Tinôco, Maria A ; Kliegel, Matthias
Assuntos: Aged ; Aged, 80 and over ; Analysis ; Biomarkers - blood ; Blood cholesterol ; Brazil ; Cholesterol ; Cognition - physiology ; Cognitive Reserve - physiology ; Fasting ; Female ; Gerontology ; Humans ; Leisure Activities ; Lipoproteins, HDL - blood ; Male ; Memory, Short-Term - physiology ; Mental Recall - physiology ; Short-term memory ; Statistics as Topic
É parte de: Dementia and geriatric cognitive disorders, 2017-01, Vol.44 (1-2), p.84-91
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Descrição: The present study set out to investigate the relation of the high-density lipoprotein cholesterol (HDL-C) level to cognitive performance and its interplay with key markers of cognitive reserve in a large sample of older adults. We assessed tests of working memory, immediate and delayed cued recall in 701 older adults from Amazonas, Brazil. The HDL-C level was derived from fasting blood samples. In addition, we interviewed individuals on their education, past occupation, and cognitive leisure activity. A critically low HDL-C level (<40 mg/dL) was significantly related to lower performance in working memory, immediate and delayed cued recall. Moderation analyses suggested that the relations of the HDL-C level to working memory and delayed cued recall were negligible in individuals with longer education, a higher cognitive level of the job, and greater engagement in cognitive leisure activity. Cognitive reserve accumulated during the life course may reduce the detrimental influences of a critically low HDL-C level on cognitive functioning in old age.
Editor: Switzerland: S. Karger AG
Idioma: Inglês

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High-Density Lipoprotein Cholesterol Level Relates to Working Memory, Immediate and Delayed Cued Recall in Brazilian Older Adults: The Role of Cognitive Reserve

Ihle, Andreas ; Gouveia, Élvio R ; Gouveia, Bruna R ; Freitas, Duarte L ; Jurema, Jefferson ; Tinôco, Maria A ; Kliegel, Matthias

Switzerland: S. Karger AG

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