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Neurotrophic factors in tension-type headache
Domingues, Renan B ; Duarte, Halina ; Rocha, Natália P ; Teixeira, Antonio L
Arquivos de neuro-psiquiatria, 2015-05, Vol.73 (5), p.420-424
[Peer Reviewed Journal]
Brazil: Academia Brasileira de Neurologia - ABNEURO
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Title:
Neurotrophic factors in tension-type headache
Author:
Domingues, Renan B
;
Duarte, Halina
;
Rocha
, Natália
P
;
Teixeira, Antonio L
Subjects:
Adult
;
ansiedade
;
Anxiety - blood
;
Anxiety - physiopathology
;
Case-Control Studies
;
cefaleia do tipo tensional
;
Cross-Sectional Studies
;
Depression - blood
;
Depression - physiopathology
;
depressão
;
Enzyme-Linked Immunosorbent Assay
;
fatores neurotróficos
;
Female
;
Humans
;
Male
;
Middle Aged
;
Nerve Growth Factors - blood
;
NEUROSCIENCES
;
PSYCHIATRY
;
Psychometrics
;
Receptors, Nerve Growth Factor - blood
;
Reference Values
;
Severity of Illness Index
;
Statistics, Nonparametric
;
Tension-Type Headache - blood
;
Tension-Type Headache - physiopathology
;
Young Adult
Is Part Of:
Arquivos de neuro-psiquiatria, 2015-05, Vol.73 (5),
p
.420-424
Notes:
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Description:
Neurotrophic factors (NF) are involved in pain regulation and a few studies have suggested that they may play a pathophysiological role in primary headaches. The aim of this study was to investigate NF levels in patients with tension type headache (TTH). We carried out a cross sectional study including 48 TTH patients and 48 age and gender matched controls. Beck Depression and Anxiety Inventories, and Headache Impact Test were recorded. Serum levels of NF were determined by ELISA. There were not significant differences between NF levels between TTH patients and controls. Patients with chronic and episodic TTH had not significant differences in NF levels. The presence of headache at the time of evaluation did not significantly alter the levels of NF. Depression and anxiety scores as well as headache impact did not correlate with NF levels. Our study suggest that the serum levels of NF are not altered in TTH.
Publisher:
Brazil: Academia Brasileira de Neurologia - ABNEURO
Language:
English;Portuguese
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