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Left ventricular compliance in acute myocardial infarction in man

BARDET, J. ; ROCHA, P. ; RIGAUD, M. ; BOURDARIAS, J. P. ; MATHIVAT, A.

Cardiovascular research, 1977-03, Vol.11 (2), p.122-131 [Periódico revisado por pares]

England: Oxford University Press

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  • Título:
    Left ventricular compliance in acute myocardial infarction in man
  • Autor: BARDET, J. ; ROCHA, P. ; RIGAUD, M. ; BOURDARIAS, J. P. ; MATHIVAT, A.
  • Assuntos: Acute Disease ; Adult ; Aged ; Blood Pressure ; Cardiac Volume ; Compliance ; Female ; Heart Ventricles - physiopathology ; Humans ; Male ; Middle Aged ; Myocardial Contraction ; Myocardial Infarction - physiopathology
  • É parte de: Cardiovascular research, 1977-03, Vol.11 (2), p.122-131
  • Notas: istex:CE896FCC0078BB48F082F784169158BEB5B067EE
    Address for correspondence and reprints: Dr J. Bardet, Department of Cardiology, Hôpital Ambroise Paré, 9, av. Ch. de Gaulle—92100 Boulogne, France.
    ark:/67375/HXZ-QTS4DWSJ-N
    ArticleID:11-2-122
    ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: Left ventricular end-diastolic pressure (P) and volume (V) were measured in 12 patients with acute myocardial infarction. It was assumed that the diastolic P-V relationship was exponential and corresponded to the formula P = be K V. In 7 patients submitted to volume loading, several data points of this relationship were obtained and at zero volume, the mean intercept with the ordinates was 0.037 ±0.015 kPa (SEM) (0.28 ±0.12 mmHg). In the other 5 patients, the P-V curve was plotted through this intercept and the pressure and volume co-ordinates obtained by control. The K coefficient (passive elastic modulus) was greater, and the normalised left ventricular compliance index (dV/VdP) was smaller in the infarct group than in the control group. This suggests decreased left ventricular compliance during the acute phase of myocardial infarction. By comparing left ventricular function curves plotted using either end-diastolic pressure or end-diastolic volume as the stretch index it is possible to evaluate the relative participation of decreased compliance and depressed contractility in global left ventricular function.
  • Editor: England: Oxford University Press
  • Idioma: Inglês
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