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Methods for the discovery and characterization of G protein-coupled receptors
Craig W Stevens
New York Humana Press c2011
Localização:
CQ - Conjunto das Químicas
(574.19245 M5923 )
(Acessar)
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Título:
Methods for the discovery and characterization of G protein-coupled receptors
Autor:
Craig W Stevens
Assuntos:
GTP-Binding Proteins
;
Receptors, G-Protein-Coupled
;
G proteins -- Receptors
;
PROTEÍNAS G
;
GENOMAS
;
BIOLOGIA MOLECULAR
Notas:
Includes bibliographical references and index.
Descrição:
In silico identification of novel G protein-coupled receptors / Alternative pre-mRNA splicing of G protein-coupled receptors / Detecting polymorphisms in G protein-coupled receptor genes / Regulation of the transcription of G protein-coupled receptor genes / Deciphering the evolution of G protein-coupled receptors in vertebrates / New approach to visualize endogenously expressed G protein-coupled receptors in tissues and living cells / Posttranslational regulation of G protein-coupled receptors / Discovering G protein-coupled receptor motifs mediating export from the endoplasmic reticulum / Identifying G protein-coupled receptor escorts, chaperones, and intracellular tethers regulating receptor density at the cell surface / Novel method for determining the kinetics of G protein-coupled receptor plasma membrane expression / Characterizing the pharmacology of G protein-coupled receptors in transfected cell lines / Novel assay technologies for the discovery of G protein-coupled receptor drugs / Discovering cell type-specific patterns of G protein-coupled receptor phosphorylation / Quantifying allosteric modulation of G protein-coupled receptors / Experimental designs for the study of receptor-receptor interactions /
r Dennis Paul -- $t / $r Chris P. Bailey and Eamonn Kelly -- $t Detecting the role of arrestins in G protein-coupled receptor regulation / $r Laura M. Bohn and Patricia H. McDonald -- $t Characterizing molecular mobility and membrane interactions of G protein-coupled receptors / $r Vladana Vukojevice, Yu Ming, and Lars Terenius -- $t Using RNA interference to downregulate G protein-coupled receptors / $r Philippe Sarret ... [et al.] -- $t Upregulating G protein-coupled receptors with receptor antagonists / $r Ellen M. Unterwald. Elucidating agonist-selective mechanisms of G protein-coupled receptor desensitization Detecting the role of arrestins in G protein-coupled receptor regulation Characterizing molecular mobility and membrane interactions of G protein-coupled receptors Using RNA interference to downregulate G protein-coupled receptors Upregulating G protein-coupled receptors with receptor antagonists
Títulos relacionados:
Série:Neuromethods 60
Editor:
New York Humana Press
Data de criação/publicação:
c2011
Formato:
xiii, 428 p ill 26 cm.
Idioma:
Inglês
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