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Experimental encephalitis caused by Taenia crassiceps cysticerci in mice

Matos-Silva, Hidelberto ; Reciputti, Bruno Pereira ; Paula, Elbio Cândido de ; Oliveira, André Luiz ; Moura, Vânia Beatriz Lopes ; Vinaud, Marina Clare ; Oliveira, Milton Adriano Pelli ; Lino-Júnior, Ruy de Souza

Arquivos de neuro-psiquiatria, 2012-04, Vol.70 (4), p.287-292 [Periódico revisado por pares]

Brazil: Academia Brasileira de Neurologia - ABNEURO

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Título:
Experimental encephalitis caused by Taenia crassiceps cysticerci in mice
Autor: Matos-Silva, Hidelberto ; Reciputti, Bruno Pereira ; Paula, Elbio Cândido de ; Oliveira, André Luiz ; Moura, Vânia Beatriz Lopes ; Vinaud, Marina Clare ; Oliveira, Milton Adriano Pelli ; Lino-Júnior, Ruy de Souza
Assuntos: Animal models ; Animals ; BALB/c ; C57BL/6 ; Classification ; Cysticercosis ; Disease Models, Animal ; Encephalitis ; Encephalitis - parasitology ; Encephalitis - pathology ; Female ; Host-Parasite Interactions ; Inflammation ; Inoculation ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Necrosis ; neurocisticercose ; Neurocysticercosis - parasitology ; Neurocysticercosis - pathology ; NEUROSCIENCES ; Parasites ; PSYCHIATRY ; Severity of Illness Index ; Taenia ; Taenia - physiology ; Taenia crassiceps
É parte de: Arquivos de neuro-psiquiatria, 2012-04, Vol.70 (4), p.287-292
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
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Descrição: To present the experimental model of neurocysticercosis (NCC) caused by Taenia crassiceps cysticerci, to describe the inflammatory process, susceptibility, or resistance of BALB/c and C57BL/6 mice to this infection, and to describe the host-parasite relationship. The animals were intracranially inoculated with initial stage T. crassiceps cysticerci. They were euthanized at 7, 30, 60, and 90 days after the inoculation. Their encephala were removed for the histopathologic analysis, classification of the parasites, and inflammatory lesions. Experimental NCC was observed on both mice lineages. BALB/c mice presented inflammatory lesions with greater intensity, inducing necrosis on late stage parasites, and with an acute inflammation pattern, while C57BL/6 mice showed greater capability on provoking early necrosis in the cysticerci, which showed a chronic inflammation pattern. This experimental model induced NCC on mice with characteristic inflammation and lesions. C57BL/6 mice were able to induce precocious necrosis of the parasites presenting inflammatory lesions with lower intensity.
Editor: Brazil: Academia Brasileira de Neurologia - ABNEURO
Idioma: Inglês;Português

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Experimental encephalitis caused by Taenia crassiceps cysticerci in mice

Matos-Silva, Hidelberto ; Reciputti, Bruno Pereira ; Paula, Elbio Cândido de ; Oliveira, André Luiz ; Moura, Vânia Beatriz Lopes ; Vinaud, Marina Clare ; Oliveira, Milton Adriano Pelli ; Lino-Júnior, Ruy de Souza

Brazil: Academia Brasileira de Neurologia - ABNEURO

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