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A STUDY ABOUT CELL ACTIVITY ON ANODIZED Ti-6Al-4V BY MEANS OF PULSED CURRENT

LUANA M. R. VASCONCELLOS ; MARIA F. L. VILLAÇA-CARVALHO ; RENATA F. PRADO ; EVELYN L. S. L. SANTOS ; NATAL N. REGONE ; MARINALDA C. PEREIRA ; EDUARDO N. CODARO ; HELOISA A. ACCIARI

Journal of engineering science & technology, 2017-05, Vol.12 (5), p.1240-1252 [Periódico revisado por pares]

Taylor's University

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  • Título:
    A STUDY ABOUT CELL ACTIVITY ON ANODIZED Ti-6Al-4V BY MEANS OF PULSED CURRENT
  • Autor: LUANA M. R. VASCONCELLOS ; MARIA F. L. VILLAÇA-CARVALHO ; RENATA F. PRADO ; EVELYN L. S. L. SANTOS ; NATAL N. REGONE ; MARINALDA C. PEREIRA ; EDUARDO N. CODARO ; HELOISA A. ACCIARI
  • Assuntos: anodizing ; osseointegration ; osteoblast activity ; Ti-6Al-4V alloy
  • É parte de: Journal of engineering science & technology, 2017-05, Vol.12 (5), p.1240-1252
  • Descrição: Titanium and some of its alloys exhibit excellent anti-corrosive and biocompatibility properties due to rapid formation of a passive film on their surfaces when exposed to the atmosphere. However, such materials presentpoor osteoindutive properties. Surfaces modified via anodization are being proposed in this study to promote a chemical interaction between implants and bone cells. For this purpose, samples in Ti-6Al-4V alloy discs were anodized in a phosphoric acid solution using pulsed current for being applied in orthopaedic implants. The pulsed current is based on duty cycle (DC), which was supplied by a square wave pulse rectifier at 100 Hz and maximum tension of 30 V. A scanning electron microscope was used to obtain images of the anodized surfaces, thus revealing the presence of uniformly distributed pores over the entire surface, measuring approximately 2 m in diameter. Osteogenic cells grown on the surface of the control and anodized samples were assayed for cytotoxicity and mineralized matrix formation. The anodized surfaces presented a higher rate of viable cells after 10 days, as well as a higher amount of nodules (p = 0.05). In conclusion, these results suggest that the nanotopography promoted by anodization using pulsed current induces beneficial modulatory effects on osteoblastic cells.
  • Editor: Taylor's University
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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