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Visceral Adipose Tissue and Skeletal Muscle Index Distribution Predicts Severe Pancreatic Fistula Development After Pancreaticoduodenectomy

Yamane, Hiroaki ; Abe, Tomoyuki ; Amano, Hironobu ; Hanada, Keiji ; Minami, Tomoyuki ; Kobayashi, Tsuyoshi ; Fukuda, Toshikatsu ; Yonehara, Shuji ; Nakahara, Masahiro ; Ohdan, Hideki ; Noriyuki, Toshio

Anticancer research, 2018-02, Vol.38 (2), p.1061-1066 [Periódico revisado por pares]

Greece: International Institute of Anticancer Research

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Título:
Visceral Adipose Tissue and Skeletal Muscle Index Distribution Predicts Severe Pancreatic Fistula Development After Pancreaticoduodenectomy
Autor: Yamane, Hiroaki ; Abe, Tomoyuki ; Amano, Hironobu ; Hanada, Keiji ; Minami, Tomoyuki ; Kobayashi, Tsuyoshi ; Fukuda, Toshikatsu ; Yonehara, Shuji ; Nakahara, Masahiro ; Ohdan, Hideki ; Noriyuki, Toshio
Assuntos: Adipose tissue ; Body composition ; Body composition (biology) ; Body mass ; Body mass index ; Body size ; Composition effects ; Fistula ; Fistulae ; Malignancy ; Multivariate analysis ; Muscles ; Musculoskeletal system ; Pancreas ; Pancreaticoduodenectomy ; Patients ; Risk analysis ; Risk factors ; Skeletal muscle ; Uranium
É parte de: Anticancer research, 2018-02, Vol.38 (2), p.1061-1066
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: In this study, we investigated the effect of body composition on pancreatic fistula (PF) development after pancreaticoduodenectomy (PD). All consecutive patients with pancreatic and extrahepatic biliary malignancy following PD who were treated between 2006 and 2016 were enrolled. PF developed in 30.3% of cases (30/99 patients), including a grade B PF in 25.3% of cases (25/99 patients) and a grade C PF in 5.1% of cases (5/99 patients). Univariate analysis identified that body mass index ≥25 kg/m , visceral adipose tissue area (VATA)/skeletal muscle index (SMI) ≥2.0, pancreatic duct diameter ≤3 mm, and drain amylase concentration (Amy) on postoperative day (POD) 1 ≥5000 U/L were significantly associated with PF (grade B, C) after PD. Multivariate analysis indicated that VATA/SMI ≥2.0 (p=0.009), pancreatic duct diameter ≤3 mm (p=0.003), and drain Amy on POD1 ≥5000 U/L (p=0.032) were independent risk factors for PF. Elevated VATA/SMI was the only preoperative key factor for PF after PD.
Editor: Greece: International Institute of Anticancer Research
Idioma: Inglês

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Visceral Adipose Tissue and Skeletal Muscle Index Distribution Predicts Severe Pancreatic Fistula Development After Pancreaticoduodenectomy

Yamane, Hiroaki ; Abe, Tomoyuki ; Amano, Hironobu ; Hanada, Keiji ; Minami, Tomoyuki ; Kobayashi, Tsuyoshi ; Fukuda, Toshikatsu ; Yonehara, Shuji ; Nakahara, Masahiro ; Ohdan, Hideki ; Noriyuki, Toshio

Greece: International Institute of Anticancer Research

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