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CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease
CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease
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CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease

Yang, Su ; Chang, Renbao ; Yang, Huiming ; Zhao, Ting ; Hong, Yan ; Kong, Ha Eun ; Sun, Xiaobo ; Qin, Zhaohui ; Jin, Peng ; Li, Shihua ; Li, Xiao-Jiang

The Journal of clinical investigation, 2017-06, Vol.127 (7), p.2719-2724 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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2
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice
Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice
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Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

Tong, Xiaoping ; Ao, Yan ; Faas, Guido C ; Nwaobi, Sinifunanya E ; Xu, Ji ; Haustein, Martin D ; Anderson, Mark A ; Mody, Istvan ; Olsen, Michelle L ; Sofroniew, Michael V ; Khakh, Baljit S

Nature neuroscience, 2014-05, Vol.17 (5), p.694-703 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
Polyglutamine tracts regulate beclin 1-dependent autophagy
Polyglutamine tracts regulate beclin 1-dependent autophagy
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Polyglutamine tracts regulate beclin 1-dependent autophagy

Ashkenazi, Avraham ; Bento, Carla F ; Ricketts, Thomas ; Vicinanza, Mariella ; Siddiqi, Farah ; Pavel, Mariana ; Squitieri, Ferdinando ; Hardenberg, Maarten C ; Imarisio, Sara ; Menzies, Fiona M ; Rubinsztein, David C

Nature (London), 2017-05, Vol.545 (7652), p.108-111 [Periódico revisado por pares]

England: Nature Publishing Group

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4
A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo
A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo
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A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo

Nakamori, Masayuki ; Panigrahi, Gagan B ; Lanni, Stella ; Gall-Duncan, Terence ; Hayakawa, Hideki ; Tanaka, Hana ; Luo, Jennifer ; Otabe, Takahiro ; Li, Jinxing ; Sakata, Akihiro ; Caron, Marie-Christine ; Joshi, Niraj ; Prasolava, Tanya ; Chiang, Karen ; Masson, Jean-Yves ; Wold, Marc S ; Wang, Xiaoxiao ; Lee, Marietta Y W T ; Huddleston, John ; Munson, Katherine M ; Davidson, Scott ; Layeghifard, Mehdi ; Edward, Lisa-Monique ; Gallon, Richard ; Santibanez-Koref, Mauro ; Murata, Asako ; Takahashi, Masanori P ; Eichler, Evan E ; Shlien, Adam ; Nakatani, Kazuhiko ; Mochizuki, Hideki ; Pearson, Christopher E

Nature genetics, 2020-02, Vol.52 (2), p.146-159 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates
Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates
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Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates

Lim, Junghyun ; Lachenmayer, M Lenard ; Wu, Shuai ; Liu, Wenchao ; Kundu, Mondira ; Wang, Rong ; Komatsu, Masaaki ; Oh, Young J ; Zhao, Yanxiang ; Yue, Zhenyu Yang, William

PLoS genetics, 2015-02, Vol.11 (2), p.e1004987 [Periódico revisado por pares]

United States: Public Library of Science

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6
Clinical and genetic data of Huntington disease in Moroccan patients
Clinical and genetic data of Huntington disease in Moroccan patients
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Clinical and genetic data of Huntington disease in Moroccan patients

Bouhouche, Ahmed ; Regragui, Wafaa ; Lamghari, Hind ; Khaldi, Khadija ; Birouk, Nazha ; Lytim, Safaa ; Bellamine, Soufiane ; Kriouile, Yamna ; Bouslam, Naima ; Haddou, El Hachmia Ait Ben ; Faris, Mustapha Alaoui ; Benomar, Ali ; Yahyaoui, Mohamed

African health sciences, 2015-01, Vol.15 (4), p.1232-1238 [Periódico revisado por pares]

Uganda: Markerere University, Medical School

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7
Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models
Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models
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Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models

Ajami, Bahareh ; Samusik, Nikolay ; Wieghofer, Peter ; Ho, Peggy P ; Crotti, Andrea ; Bjornson, Zach ; Prinz, Marco ; Fantl, Wendy J ; Nolan, Garry P ; Steinman, Lawrence

Nature neuroscience, 2018-04, Vol.21 (4), p.541-551 [Periódico revisado por pares]

United States: Nature Publishing Group

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8
Choosing an animal model for the study of Huntington's disease
Choosing an animal model for the study of Huntington's disease
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Choosing an animal model for the study of Huntington's disease

Pouladi, Mahmoud A ; Morton, A Jennifer ; Hayden, Michael R

Nature reviews. Neuroscience, 2013-10, Vol.14 (10), p.708-721 [Periódico revisado por pares]

England: Nature Publishing Group

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9
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease
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Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease

Zeitler, Bryan ; Froelich, Steven ; Marlen, Kimberly ; Shivak, David A ; Yu, Qi ; Li, Davis ; Pearl, Jocelynn R ; Miller, Jeffrey C ; Zhang, Lei ; Paschon, David E ; Hinkley, Sarah J ; Ankoudinova, Irina ; Lam, Stephen ; Guschin, Dmitry ; Kopan, Lexi ; Cherone, Jennifer M ; Nguyen, Hoang-Oanh B ; Qiao, Guijuan ; Ataei, Yasaman ; Mendel, Matthew C ; Amora, Rainier ; Surosky, Richard ; Laganiere, Josee ; Vu, B Joseph ; Narayanan, Anand ; Sedaghat, Yalda ; Tillack, Karsten ; Thiede, Christina ; Gärtner, Annette ; Kwak, Seung ; Bard, Jonathan ; Mrzljak, Ladislav ; Park, Larry ; Heikkinen, Taneli ; Lehtimäki, Kimmo K ; Svedberg, Marie M ; Häggkvist, Jenny ; Tari, Lenke ; Tóth, Miklós ; Varrone, Andrea ; Halldin, Christer ; Kudwa, Andrea E ; Ramboz, Sylvie ; Day, Michelle ; Kondapalli, Jyothisri ; Surmeier, D James ; Urnov, Fyodor D ; Gregory, Philip D ; Rebar, Edward J ; Muñoz-Sanjuán, Ignacio ; Zhang, H Steve

Nature medicine, 2019-07, Vol.25 (7), p.1131-1142 [Periódico revisado por pares]

United States: Nature Publishing Group

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10
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease
Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease
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Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease

Paul, Bindu D ; Sbodio, Juan I ; Xu, Risheng ; Vandiver, M Scott ; Cha, Jiyoung Y ; Snowman, Adele M ; Snyder, Solomon H

Nature (London), 2014-05, Vol.509 (7498), p.96-100 [Periódico revisado por pares]

England: Nature Publishing Group

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