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Research Advancements on Fluorinated and Non-Fluorinated 4- Phenyl(thio)ureido-Substituted 2,2-Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants
Research Advancements on Fluorinated and Non-Fluorinated 4- Phenyl(thio)ureido-Substituted 2,2-Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants
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Research Advancements on Fluorinated and Non-Fluorinated 4- Phenyl(thio)ureido-Substituted 2,2-Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants

Pirotte, Bernard ; Florence, Xavier ; Goffin, Eric ; Leleux, Fabienne ; Lebrun, Philippe

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2022-01, Vol.18 (8), p.884-894 [Periódico revisado por pares]

Netherlands: Bentham Science Publishers Ltd

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12
Synthesis, Pharmacological and Structural Characterization, and Thermodynamic Aspects of GluA2-Positive Allosteric Modulators with a 3,4-Dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxide Scaffold
Synthesis, Pharmacological and Structural Characterization, and Thermodynamic Aspects of GluA2-Positive Allosteric Modulators with a 3,4-Dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxide Scaffold
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Synthesis, Pharmacological and Structural Characterization, and Thermodynamic Aspects of GluA2-Positive Allosteric Modulators with a 3,4-Dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxide Scaffold

Nørholm, Ann-Beth ; Francotte, Pierre ; Olsen, Lars ; Krintel, Christian ; Frydenvang, Karla ; Goffin, Eric ; Challal, Sylvie ; Danober, Laurence ; Botez-Pop, Iuliana ; Lestage, Pierre ; Pirotte, Bernard ; Kastrup, Jette S

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8736-8745 [Periódico revisado por pares]

United States: American Chemical Society

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13
Differential Effects of Cocaine on Dopamine Neuron Firing in Awake and Anesthetized Rats
Differential Effects of Cocaine on Dopamine Neuron Firing in Awake and Anesthetized Rats
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Differential Effects of Cocaine on Dopamine Neuron Firing in Awake and Anesthetized Rats

KOULCHITSKY, Stanislav ; DE BACKER, Benjamin ; QUERTEMONT, Etienne ; CHARLIER, Corinne ; SEUTIN, Vincent

Neuropsychopharmacology (New York, N.Y.), 2012-06, Vol.37 (7), p.1559-1571 [Periódico revisado por pares]

Basingstoke: Nature Publishing Group

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14
4-Phenylureido/thioureido-substituted 2,2-dimethylchroman analogs of cromakalim bearing a bulky ‘carbamate’ moiety at the 6-position as potent inhibitors of glucose-sensitive insulin secretion
4-Phenylureido/thioureido-substituted 2,2-dimethylchroman analogs of cromakalim bearing a bulky ‘carbamate’ moiety at the 6-position as potent inhibitors of glucose-sensitive insulin secretion
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4-Phenylureido/thioureido-substituted 2,2-dimethylchroman analogs of cromakalim bearing a bulky ‘carbamate’ moiety at the 6-position as potent inhibitors of glucose-sensitive insulin secretion

Pirotte, Bernard ; Florence, Xavier ; Goffin, Eric ; Medeiros, Marlen Borges ; de Tullio, Pascal ; Lebrun, Philippe

European journal of medicinal chemistry, 2016-10, Vol.121, p.338-351 [Periódico revisado por pares]

France: Elsevier Masson SAS

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15
Positive Allosteric Modulators of 2‑Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4‑Cyclopropyl-3,4-dihydro‑2H‑1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4‑Cyclopropyl-3,4-dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxides
Positive Allosteric Modulators of 2‑Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4‑Cyclopropyl-3,4-dihydro‑2H‑1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4‑Cyclopropyl-3,4-dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxides
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Positive Allosteric Modulators of 2‑Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4‑Cyclopropyl-3,4-dihydro‑2H‑1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4‑Cyclopropyl-3,4-dihydro‑2H‑1,2,4-benzothiadiazine 1,1-Dioxides

Francotte, Pierre ; Nørholm, Ann-Beth ; Deva, Taru ; Olsen, Lars ; Frydenvang, Karla ; Goffin, Eric ; Fraikin, Pierre ; de Tullio, Pascal ; Challal, Sylvie ; Thomas, Jean-Yves ; Iop, Fabrice ; Louis, Caroline ; Botez-Pop, Iuliana ; Lestage, Pierre ; Danober, Laurence ; Kastrup, Jette S ; Pirotte, Bernard

Journal of medicinal chemistry, 2014-11, Vol.57 (22), p.9539-9553 [Periódico revisado por pares]

United States: American Chemical Society

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16
Activation of D2 autoreceptors alters cocaine-induced locomotion and slows down local field oscillations in the rat ventral tegmental area
Activation of D2 autoreceptors alters cocaine-induced locomotion and slows down local field oscillations in the rat ventral tegmental area
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Activation of D2 autoreceptors alters cocaine-induced locomotion and slows down local field oscillations in the rat ventral tegmental area

Koulchitsky, Stanislav ; Delairesse, Charlotte ; Beeken, Thom ; Monteforte, Alexandre ; Dethier, Julie ; Quertemont, Etienne ; Findeisen, Rolf ; Bullinger, Eric ; Seutin, Vincent

Neuropharmacology, 2016-09, Vol.108, p.120-127 [Periódico revisado por pares]

England: Elsevier Ltd

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17
Deciphering Structure–Activity Relationships in a Series of 2,2‐Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants
Deciphering Structure–Activity Relationships in a Series of 2,2‐Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants
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Deciphering Structure–Activity Relationships in a Series of 2,2‐Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants

Pirotte, Bernard ; Florence, Xavier ; Goffin, Eric ; Lebrun, Philippe

ChemMedChem, 2017-11, Vol.12 (21), p.1810-1817 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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18
Development of Thiophenic Analogues of Benzothiadiazine Dioxides as New Powerful Potentiators of 2‑Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptors
Development of Thiophenic Analogues of Benzothiadiazine Dioxides as New Powerful Potentiators of 2‑Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptors
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Development of Thiophenic Analogues of Benzothiadiazine Dioxides as New Powerful Potentiators of 2‑Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptors

Francotte, Pierre ; Goffin, Eric ; Fraikin, Pierre ; Graindorge, E ; Lestage, Pierre ; Danober, Laurence ; Challal, Sylvie ; Rogez, Nathalie ; Nosjean, Olivier ; Caignard, Daniel-Henri ; Pirotte, Bernard ; de Tullio, Pascal

Journal of medicinal chemistry, 2013-10, Vol.56 (20), p.7838-7850 [Periódico revisado por pares]

United States: American Chemical Society

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19
Physicochemical Property Determinants of Oral Absorption for PROTAC Protein Degraders
Physicochemical Property Determinants of Oral Absorption for PROTAC Protein Degraders
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Physicochemical Property Determinants of Oral Absorption for PROTAC Protein Degraders

Hornberger, Keith R. ; Araujo, Erika M. V.

Journal of medicinal chemistry, 2023-06, Vol.66 (12), p.8281-8287 [Periódico revisado por pares]

United States: American Chemical Society

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20
Resolution of inflammation: a new therapeutic frontier
Resolution of inflammation: a new therapeutic frontier
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Resolution of inflammation: a new therapeutic frontier

Fullerton, James N ; Gilroy, Derek W

Nature reviews. Drug discovery, 2016-08, Vol.15 (8), p.551-567 [Periódico revisado por pares]

England: Nature Publishing Group

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