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Refinado por: assunto: Huntington Disease - Genetics remover assunto: Life Sciences & Biomedicine remover
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1
Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis
Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis
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Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

Kordasiewicz, Holly B. ; Stanek, Lisa M. ; Wancewicz, Edward V. ; Mazur, Curt ; McAlonis, Melissa M. ; Pytel, Kimberly A. ; Artates, Jonathan W. ; Weiss, Andreas ; Cheng, Seng H. ; Shihabuddin, Lamya S. ; Hung, Gene ; Bennett, C. Frank ; Cleveland, Don W.

Neuron (Cambridge, Mass.), 2012-06, Vol.74 (6), p.1031-1044 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease
Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease
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Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

Hermel, E ; Gafni, J ; Propp, S S ; Leavitt, B R ; Wellington, C L ; Young, J E ; Hackam, A S ; Logvinova, A V ; Peel, A L ; Chen, S F ; Hook, V ; Singaraja, R ; Krajewski, S ; Goldsmith, P C ; Ellerby, H M ; Hayden, M R ; Bredesen, D E ; Ellerby, L M

Cell death and differentiation, 2004-04, Vol.11 (4), p.424-438 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Brain Structure in Preclinical Huntington’s Disease
Brain Structure in Preclinical Huntington’s Disease
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Brain Structure in Preclinical Huntington’s Disease

Paulsen, Jane S. ; Magnotta, Vince A. ; Mikos, Ania E. ; Paulson, Henry L. ; Penziner, Elizabeth ; Andreasen, Nancy C. ; Nopoulos, Peg C.

Biological psychiatry (1969), 2006, Vol.59 (1), p.57-63 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Protection by dietary restriction in the YAC128 mouse model of Huntington's disease: Relation to genes regulating histone acetylation and HTT
Protection by dietary restriction in the YAC128 mouse model of Huntington's disease: Relation to genes regulating histone acetylation and HTT
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Protection by dietary restriction in the YAC128 mouse model of Huntington's disease: Relation to genes regulating histone acetylation and HTT

Moreno, Cesar L ; Ehrlich, Michelle E ; Mobbs, Charles V

Neurobiology of disease, 2016-01, Vol.85, p.25-34 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice
Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice
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Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice

Schilling, Gabriele ; Savonenko, Alena V. ; Klevytska, Alexandra ; Morton, Johanna L. ; Tucker, Stina M. ; Poirier, Michelle ; Gale, Alexa ; Chan, Ning ; Gonzales, Vicky ; Slunt, Hilda H. ; Coonfield, Michael L. ; Jenkins, Nancy A. ; Copeland, Neal G. ; Ross, Christopher A. ; Borchelt, David R.

Human molecular genetics, 2004-08, Vol.13 (15), p.1599-1610 [Periódico revisado por pares]

Oxford: Oxford University Press

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6
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation
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Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation

Valenza, Marta ; Carroll, Jeffrey B. ; Leoni, Valerio ; Bertram, Lisa N. ; Björkhem, Ingeman ; Singaraja, Roshni R. ; Di Donato, Stefano ; Lutjohann, Dieter ; Hayden, Michael R. ; Cattaneo, Elena

Human molecular genetics, 2007-09, Vol.16 (18), p.2187-2198 [Periódico revisado por pares]

Oxford: Oxford University Press

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7
Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease
Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease
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Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease

Senatorov, Vladimir V ; Charles, Vinod ; Reddy, P.H ; Tagle, Dan A ; Chuang, De-Maw

Molecular and cellular neuroscience, 2003-03, Vol.22 (3), p.285-297 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue
Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue
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Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue

PEEL, Alyson L ; RAO, Ram V ; COTTRELL, Barbara A ; HAYDEN, Michael R ; ELLERBY, Lisa M ; BREDESEN, Dale E

Human molecular genetics, 2001-07, Vol.10 (15), p.1531-1538 [Periódico revisado por pares]

Oxford: Oxford University Press

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9
Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease
Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease
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Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease

Desplats, Paula A ; Lambert, James R ; Thomas, Elizabeth A

Neurobiology of disease, 2008-09, Vol.31 (3), p.298-308 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Characterization of Huntingtin Pathologic Fragments in Human Huntington Disease, Transgenic Mice, and Cell Models
Characterization of Huntingtin Pathologic Fragments in Human Huntington Disease, Transgenic Mice, and Cell Models
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Characterization of Huntingtin Pathologic Fragments in Human Huntington Disease, Transgenic Mice, and Cell Models

Schilling, Gabriele ; Klevytska, Alexandra ; Tebbenkamp, Andrew T. N ; Juenemann, Katrin ; Cooper, Jillian ; Gonzales, Victoria ; Slunt, Hilda ; Poirer, Michelle ; Ross, Christopher A ; Borchelt, David R

Journal of neuropathology and experimental neurology, 2007-04, Vol.66 (4), p.313-320 [Periódico revisado por pares]

Hagerstown, MD: American Association of Neuropathologists, Inc

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