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1 |
Material Type: Artigo
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cGMP and mitochondrial K+ channels—Compartmentalized but closely connected in cardioprotectionLukowski, Robert ; Cruz Santos, Melanie ; Kuret, Anna ; Ruth, PeterBritish journal of pharmacology, 2022-06, Vol.179 (11), p.2344-2360 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Mechanistic insights on novel small molecule allosteric activators of cGMP-dependent protein kinase PKG1αTawa, Paul ; Zhang, Lei ; Metwally, Essam ; Hou, Yan ; McCoy, Mark A. ; Seganish, W. Michael ; Zhang, Rumin ; Frank, Emily ; Sheth, Payal ; Hanisak, Jennifer ; Sondey, Christopher ; Bauman, David ; Soriano, AileenThe Journal of biological chemistry, 2022-09, Vol.298 (9), p.102284-102284, Article 102284 [Periódico revisado por pares]Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidneyStehle, Daniel ; Xu, Min Ze ; Schomber, Tibor ; Hahn, Michael G. ; Schweda, Frank ; Feil, Susanne ; Kraehling, Jan R. ; Eitner, Frank ; Patzak, Andreas ; Sandner, Peter ; Feil, Robert ; Bénardeau, AgnèsBritish journal of pharmacology, 2022-06, Vol.179 (11), p.2476-2489 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Soluble GC stimulators and activators: Past, present and futureSandner, Peter ; Follmann, Markus ; Becker-Pelster, Eva ; Hahn, Michael G ; Meier, Christian ; Freitas, Cecilia ; Roessig, Lothar ; Stasch, Johannes-PeterBritish journal of pharmacology, 2021-12 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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Oxidation of cysteine 117 stimulates constitutive activation of the type Iα cGMP-dependent protein kinaseSheehe, Jessica L. ; Bonev, Adrian D. ; Schmoker, Anna M. ; Ballif, Bryan A. ; Nelson, Mark T. ; Moon, Thomas M. ; Dostmann, Wolfgang R.The Journal of biological chemistry, 2018-10, Vol.293 (43), p.16791-16802 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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The PDE6 mutation in the rd10 retinal degeneration mouse model causes protein mislocalization and instability and promotes cell death through increased ion influxWang, Tian ; Reingruber, Jürgen ; Woodruff, Michael L. ; Majumder, Anurima ; Camarena, Andres ; Artemyev, Nikolai O. ; Fain, Gordon L. ; Chen, JeannieThe Journal of biological chemistry, 2018-10, Vol.293 (40), p.15332-15346 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Constitutive protein kinase G activation exacerbates stress‐induced cardiomyopathySchwaerzer, Gerburg K. ; Casteel, Darren E. ; Cividini, Federico ; Kalyanaraman, Hema ; Zhuang, Shunhui ; Gu, Yusu ; Dalton, Nancy D. ; Peterson, Kirk L. ; Dillmann, Wolfgang H. ; Boss, Gerry R. ; Pilz, Renate B.British journal of pharmacology, 2022-06, Vol.179 (11), p.2413-2429 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Mechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinaseByun, Jung Ah ; Van, Katherine ; Huang, Jinfeng ; Henning, Philipp ; Franz, Eugen ; Akimoto, Madoka ; Herberg, Friedrich W. ; Kim, Choel ; Melacini, GiuseppeThe Journal of biological chemistry, 2020-06, Vol.295 (25), p.8480-8491 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Rosa laevigata Michx‐induced improvement of vascular dysfunction through PI3K/AKT‐mediated NO‐cGMP pathway in endothelial cells and 2K1C hypertensive ratKim, Hye Yoom ; Ahn, You Mee ; Hong, Mi Hyeon Hong ; Yoon, Jung Joo ; Lee, Yun Jung ; Kang, Dae Gill ; Lee, Ho SubThe FASEB journal, 2019-04, Vol.33 (S1), p.691.4-691.4 [Periódico revisado por pares]The Federation of American Societies for Experimental BiologyTexto completo disponível |
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Material Type: Artigo
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Established and emerging therapeutic uses of PDE type 5 inhibitors in cardiovascular diseaseTzoumas, Nikolaos ; Farrah, Tariq E. ; Dhaun, Neeraj ; Webb, David J.British journal of pharmacology, 2020-12, Vol.177 (24), p.5467-5488 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |