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Development of Selective Covalent Janus Kinase 3 Inhibitors
Development of Selective Covalent Janus Kinase 3 Inhibitors
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Development of Selective Covalent Janus Kinase 3 Inhibitors

Tan, Li ; Akahane, Koshi ; McNally, Randall ; Reyskens, Kathleen M. S. E ; Ficarro, Scott B ; Liu, Suhu ; Herter-Sprie, Grit S ; Koyama, Shohei ; Pattison, Michael J ; Labella, Katherine ; Johannessen, Liv ; Akbay, Esra A ; Wong, Kwok-Kin ; Frank, David A ; Marto, Jarrod A ; Look, Thomas A ; Arthur, J. Simon C ; Eck, Michael J ; Gray, Nathanael S

Journal of medicinal chemistry, 2015-08, Vol.58 (16), p.6589-6606 [Periódico revisado por pares]

United States: American Chemical Society

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2
X‑ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor
X‑ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor
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X‑ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor

Elkins, Jonathan M ; Wang, Jing ; Deng, Xianming ; Pattison, Michael J ; Arthur, J. Simon C ; Erazo, Tatiana ; Gomez, Nestor ; Lizcano, Jose M ; Gray, Nathanael S ; Knapp, Stefan

Journal of medicinal chemistry, 2013-06, Vol.56 (11), p.4413-4421 [Periódico revisado por pares]

United States: American Chemical Society

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3
Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y12 Receptor
Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y12 Receptor
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Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y12 Receptor

Douglass, James G ; Patel, Roshni I ; Yerxa, Benjamin R ; Shaver, Sammy R ; Watson, Paul S ; Bednarski, Krzysztof ; Plourde, Robert ; Redick, Catherine C ; Brubaker, Kurt ; Jones, Arthur C ; Boyer, José L

Journal of medicinal chemistry, 2008-02, Vol.51 (4), p.1007-1025 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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4
Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y 12 Receptor
Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y 12 Receptor
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Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y 12 Receptor

Douglass, James G. ; Patel, Roshni I. ; Yerxa, Benjamin R. ; Shaver, Sammy R. ; Watson, Paul S. ; Bednarski, Krzysztof ; Plourde, Robert ; Redick, Catherine C. ; Brubaker, Kurt ; Jones, Arthur C. ; Boyer, José L.

Journal of medicinal chemistry, 2008-02, Vol.51 (4), p.1007-1025 [Periódico revisado por pares]

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5
Isoxicam and related 4-hydroxy-N-isoxazolyl-2H-1,2-benzothiazine-3-carboxamide, 1,1-dioxides. Potent nonsteroidal antiinflammatory agents
Isoxicam and related 4-hydroxy-N-isoxazolyl-2H-1,2-benzothiazine-3-carboxamide, 1,1-dioxides. Potent nonsteroidal antiinflammatory agents
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Isoxicam and related 4-hydroxy-N-isoxazolyl-2H-1,2-benzothiazine-3-carboxamide, 1,1-dioxides. Potent nonsteroidal antiinflammatory agents

Zinnes, Harold ; Sircar, Jagadish C ; Lindo, Neil ; Schwartz, Martin L ; Fabian, Arthur C ; Shavel, John ; Kasulanis, Charles F ; Genzer, Jerome D ; Lutomski, Charles ; DiPasquale, G

Journal of medicinal chemistry, 1982-01, Vol.25 (1), p.12-18 [Periódico revisado por pares]

United States: American Chemical Society

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6
Additions and Corrections - 3-Substituted 2-Thiohydrouracils. Synthesis and Antitubercular and Antineoplastic Activities
Additions and Corrections - 3-Substituted 2-Thiohydrouracils. Synthesis and Antitubercular and Antineoplastic Activities
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Additions and Corrections - 3-Substituted 2-Thiohydrouracils. Synthesis and Antitubercular and Antineoplastic Activities

Glasser, Arthur C ; Doughty, Richard M

Journal of medicinal chemistry, 1967-11, Vol.10 (6), p.1197-1197 [Periódico revisado por pares]

American Chemical Society

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7
3-Substituted 2-Thiohydrouracils. Synthesis and Antitubercular and Antineoplastic Activities
3-Substituted 2-Thiohydrouracils. Synthesis and Antitubercular and Antineoplastic Activities
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3-Substituted 2-Thiohydrouracils. Synthesis and Antitubercular and Antineoplastic Activities

Glasser, Arthur C ; Doughty, Richard M

Journal of medicinal chemistry, 1966-05, Vol.9 (3), p.351-353 [Periódico revisado por pares]

United States: American Chemical Society

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8
Design, Synthesis, and Pharmacological Evaluation of N‑Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase‑4 Inhibitors
Design, Synthesis, and Pharmacological Evaluation of N‑Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase‑4 Inhibitors
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Design, Synthesis, and Pharmacological Evaluation of N‑Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase‑4 Inhibitors

Kümmerle, Arthur E ; Schmitt, Martine ; Cardozo, Suzana V. S ; Lugnier, Claire ; Villa, Pascal ; Lopes, Alexandra B ; Romeiro, Nelilma C ; Justiniano, Hélène ; Martins, Marco A ; Fraga, Carlos A. M ; Bourguignon, Jean-Jacques ; Barreiro, Eliezer J

Journal of medicinal chemistry, 2012-09, Vol.55 (17), p.7525-7545 [Periódico revisado por pares]

United States: American Chemical Society

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9
Structure–Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists
Structure–Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists
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Structure–Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists

Selfridge, Brandon R ; Wang, Xiaohui ; Zhang, Yingning ; Yin, Hang ; Grace, Peter M ; Watkins, Linda R ; Jacobson, Arthur E ; Rice, Kenner C

Journal of medicinal chemistry, 2015-06, Vol.58 (12), p.5038-5052 [Periódico revisado por pares]

United States: American Chemical Society

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10
Potent Anti-SARS-CoV‑2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L
Potent Anti-SARS-CoV‑2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L
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Potent Anti-SARS-CoV‑2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L

Ashhurst, Anneliese S. ; Tang, Arthur H. ; Fajtová, Pavla ; Yoon, Michael C. ; Aggarwal, Anupriya ; Bedding, Max J. ; Stoye, Alexander ; Beretta, Laura ; Pwee, Dustin ; Drelich, Aleksandra ; Skinner, Danielle ; Li, Linfeng ; Meek, Thomas D. ; McKerrow, James H. ; Hook, Vivian ; Tseng, Chien-Te ; Larance, Mark ; Turville, Stuart ; Gerwick, William H. ; O’Donoghue, Anthony J. ; Payne, Richard J.

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.2956-2970 [Periódico revisado por pares]

United States: American Chemical Society

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