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Material Type: Artigo
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Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktailHansen, Johanna ; Baum, Alina ; Pascal, Kristen E ; Russo, Vincenzo ; Giordano, Stephanie ; Wloga, Elzbieta ; Fulton, Benjamin O ; Yan, Ying ; Koon, Katrina ; Patel, Krunal ; Chung, Kyung Min ; Hermann, Aynur ; Ullman, Erica ; Cruz, Jonathan ; Rafique, Ashique ; Huang, Tammy ; Fairhurst, Jeanette ; Libertiny, Christen ; Malbec, Marine ; Lee, Wen-Yi ; Welsh, Richard ; Farr, Glen ; Pennington, Seth ; Deshpande, Dipali ; Cheng, Jemmie ; Watty, Anke ; Bouffard, Pascal ; Babb, Robert ; Levenkova, Natasha ; Chen, Calvin ; Zhang, Bojie ; Romero Hernandez, Annabel ; Saotome, Kei ; Zhou, Yi ; Franklin, Matthew ; Sivapalasingam, Sumathi ; Lye, David Chien ; Weston, Stuart ; Logue, James ; Haupt, Robert ; Frieman, Matthew ; Chen, Gang ; Olson, William ; Murphy, Andrew J ; Stahl, Neil ; Yancopoulos, George D ; Kyratsous, Christos AScience (American Association for the Advancement of Science), 2020-08, Vol.369 (6506), p.1010-1014 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerabilityBrouwer, Philip J M ; Caniels, Tom G ; van der Straten, Karlijn ; Snitselaar, Jonne L ; Aldon, Yoann ; Bangaru, Sandhya ; Torres, Jonathan L ; Okba, Nisreen M A ; Claireaux, Mathieu ; Kerster, Gius ; Bentlage, Arthur E H ; van Haaren, Marlies M ; Guerra, Denise ; Burger, Judith A ; Schermer, Edith E ; Verheul, Kirsten D ; van der Velde, Niels ; van der Kooi, Alex ; van Schooten, Jelle ; van Breemen, Mariëlle J ; Bijl, Tom P L ; Sliepen, Kwinten ; Aartse, Aafke ; Derking, Ronald ; Bontjer, Ilja ; Kootstra, Neeltje A ; Wiersinga, W Joost ; Vidarsson, Gestur ; Haagmans, Bart L ; Ward, Andrew B ; de Bree, Godelieve J ; Sanders, Rogier W ; van Gils, Marit JScience (American Association for the Advancement of Science), 2020-08, Vol.369 (6504), p.643-650 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Deep learning guided optimization of human antibody against SARS-CoV-2 variants with broad neutralizationShan, Sisi ; Luo, Shitong ; Yang, Ziqing ; Hong, Junxian ; Su, Yufeng ; Ding, Fan ; Fu, Lili ; Li, Chenyu ; Chen, Peng ; Ma, Jianzhu ; Shi, Xuanling ; Zhang, Qi ; Berger, Bonnie ; Zhang, Linqi ; Peng, JianProceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (11), p.e2122954119-e2122954119 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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COVID-19 in Africa: Dampening the storm?Mbow, Moustapha ; Lell, Bertrand ; Jochems, Simon P ; Cisse, Badara ; Mboup, Souleymane ; Dewals, Benjamin G ; Jaye, Assan ; Dieye, Alioune ; Yazdanbakhsh, MariaScience (American Association for the Advancement of Science), 2020-08, Vol.369 (6504), p.624-626 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphavirusesMalonis, Ryan J ; Earnest, James T ; Kim, Arthur S ; Angeliadis, Matthew ; Holtsberg, Frederick W ; Aman, M Javad ; Jangra, Rohit K ; Chandran, Kartik ; Daily, Johanna P ; Diamond, Michael S ; Kielian, Margaret ; Lai, Jonathan RProceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (37) [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse modelsHuang, Deli ; Abbott, Robert K. ; Havenar-Daughton, Colin ; Skog, Patrick D. ; Al-Kolla, Rita ; Groschel, Bettina ; Blane, Tanya R. ; Menis, Sergey ; Tran, Jenny Tuyet ; Thinnes, Theresa C. ; Volpi, Sabrina A. ; Liguori, Alessia ; Schiffner, Torben ; Villegas, Sophia M. ; Kalyuzhniy, Oleksandr ; Pintea, Mark ; Voss, James E. ; Phelps, Nicole ; Tingle, Ryan ; Rodriguez, Alberto R. ; Martin, Greg ; Kupryianov, Sergey ; deCamp, Allan ; Schief, William R. ; Nemazee, David ; Crotty, ShaneProceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (37), p.22920-22931 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Engineering pan-HIV-1 neutralization potency through multispecific antibody avidityRujas, Edurne ; Cui, Hong ; Burnie, Jonathan ; Aschner, Clare Burn ; Zhao, Tiantian ; Insausti, Sara ; Muthuraman, Krithika ; Semesi, Anthony ; Ophel, Jasper ; Nieva, Jose L ; Seaman, Michael S ; Guzzo, Christina ; Treanor, Bebhinn ; Julien, Jean-PhilippeProceedings of the National Academy of Sciences - PNAS, 2022-01, Vol.119 (4), p.1 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodiesXie, Zhenfei ; Lin, Ying-Cing ; Steichen, Jon M ; Ozorowski, Gabriel ; Kratochvil, Sven ; Ray, Rashmi ; Torres, Jonathan L ; Liguori, Alessia ; Kalyuzhniy, Oleksandr ; Wang, Xuesong ; Warner, John E ; Weldon, Stephanie R ; Dale, Gordon A ; Kirsch, Kathrin H ; Nair, Usha ; Baboo, Sabyasachi ; Georgeson, Erik ; Adachi, Yumiko ; Kubitz, Michael ; Jackson, Abigail M ; Richey, Sara T ; Volk, Reid M ; Lee, Jeong Hyun ; Diedrich, Jolene K ; Prum, Thavaleak ; Falcone, Samantha ; Himansu, Sunny ; Carfi, Andrea ; Yates, 3rd, John R ; Paulson, James C ; Sok, Devin ; Ward, Andrew B ; Schief, William R ; Batista, Facundo DScience (American Association for the Advancement of Science), 2024-05, Vol.384 (6697), p.eadk0582-eadk0582 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primatesSteichen, Jon M ; Phung, Ivy ; Salcedo, Eugenia ; Ozorowski, Gabriel ; Willis, Jordan R ; Baboo, Sabyasachi ; Liguori, Alessia ; Cottrell, Christopher A ; Torres, Jonathan L ; Madden, Patrick J ; Ma, Krystal M ; Sutton, Henry J ; Lee, Jeong Hyun ; Kalyuzhniy, Oleksandr ; Allen, Joel D ; Rodriguez, Oscar L ; Adachi, Yumiko ; Mullen, Tina-Marie ; Georgeson, Erik ; Kubitz, Michael ; Burns, Alison ; Barman, Shawn ; Mopuri, Rohini ; Metz, Amanda ; Altheide, Tasha K ; Diedrich, Jolene K ; Saha, Swati ; Shields, Kaitlyn ; Schultze, Steven E ; Smith, Melissa L ; Schiffner, Torben ; Burton, Dennis R ; Watson, Corey T ; Bosinger, Steven E ; Crispin, Max ; Yates, 3rd, John R ; Paulson, James C ; Ward, Andrew B ; Sok, Devin ; Crotty, Shane ; Schief, William RScience (American Association for the Advancement of Science), 2024-05, Vol.384 (6697), p.eadj8321-eadj8321 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2Chi, Xiangyang ; Yan, Renhong ; Zhang, Jun ; Zhang, Guanying ; Zhang, Yuanyuan ; Hao, Meng ; Zhang, Zhe ; Fan, Pengfei ; Dong, Yunzhu ; Yang, Yilong ; Chen, Zhengshan ; Guo, Yingying ; Zhang, Jinlong ; Li, Yaning ; Song, Xiaohong ; Chen, Yi ; Xia, Lu ; Fu, Ling ; Hou, Lihua ; Xu, Junjie ; Yu, Changming ; Li, Jianmin ; Zhou, Qiang ; Chen, WeiScience (American Association for the Advancement of Science), 2020-08, Vol.369 (6504), p.650-655 [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |