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1 |
Material Type: Artigo
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Physiochemical drug properties associated with in vivo toxicological outcomesHughes, Jason D. ; Blagg, Julian ; Price, David A. ; Bailey, Simon ; DeCrescenzo, Gary A. ; Devraj, Rajesh V. ; Ellsworth, Edmund ; Fobian, Yvette M. ; Gibbs, Michael E. ; Gilles, Richard W. ; Greene, Nigel ; Huang, Enoch ; Krieger-Burke, Teresa ; Loesel, Jens ; Wager, Travis ; Whiteley, Larry ; Zhang, YaoBioorganic & medicinal chemistry, 2008-09, Vol.18 (17), p.4872-4875 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Anti-HCV and Zika activities of ribavirin C-nucleosides analoguesGonzalez, Simon ; Brzuska, Gabriela ; Ouarti, Abdelhakim ; Gallier, Florian ; Solarte, Carmen ; Ferry, Angélique ; Uziel, Jacques ; Krol, Ewelina ; Lubin-Germain, NadègeBioorganic & medicinal chemistry, 2022-08, Vol.68, p.116858-116858, Article 116858 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Drug screening approach against mycobacterial fatty acyl-AMP ligase FAAL32 renews the interest of the salicylanilide pharmacophore in the fight against tuberculosisLe, Nguyen-Hung ; Constant, Patricia ; Tranier, Samuel ; Nahoum, Virginie ; Guillet, Valérie ; Maveyraud, Laurent ; Daffé, Mamadou ; Mourey, Lionel ; Verhaeghe, Pierre ; Marrakchi, HediaBioorganic & medicinal chemistry, 2022-10, Vol.71, p.116938-116938, Article 116938 [Periódico revisado por pares]Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Synthesis and evaluation of 2,9-disubstituted-1,10-phenanthroline derivatives as G-quadruplex bindersFigueiredo, Joana ; Carreira-Barral, Israel ; Quesada, Roberto ; Mergny, Jean-Louis ; Cruz, CarlaBioorganic & medicinal chemistry, 2022-11, Vol.73, p.116971-116971, Article 116971 [Periódico revisado por pares]Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Mitochondria-targeted cationic porphyrin-triphenylamine hybrids for enhanced two-photon photodynamic therapyHammerer, Fabien ; Poyer, Florent ; Fourmois, Laura ; Chen, Su ; Garcia, Guillaume ; Teulade-Fichou, Marie-Paule ; Maillard, Philippe ; Mahuteau-Betzer, FlorenceBioorganic & medicinal chemistry, 2018-01, Vol.26 (1), p.107-118 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomicsSchneekloth, Ashley R. ; Pucheault, Mathieu ; Tae, Hyun Seop ; Crews, Craig M.Bioorganic & medicinal chemistry, 2008-11, Vol.18 (22), p.5904-5908 [Periódico revisado por pares]Amsterdam: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Aurones and derivatives as promising New Delhi metallo-β-lactamase (NDM-1) inhibitorsCaburet, Jérémy ; Verdirosa, Federica ; Moretti, Matis ; Roulier, Brayan ; Simoncelli, Giorgia ; Haudecoeur, Romain ; Ghazi, Somayeh ; Jamet, Hélène ; Docquier, Jean-Denis ; Boucherle, Benjamin ; Peuchmaur, MarineBioorganic & medicinal chemistry, 2024-01, Vol.97, p.117559-117559, Article 117559 [Periódico revisado por pares]England: ElsevierTexto completo disponível |
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Material Type: Artigo
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Rational modification, synthesis and biological evaluation of N-substituted phthalazinone derivatives designed to target interleukine-15 proteinSmadja, Jimmy ; Quéméner, Agnès ; Maillasson, Mike ; Sicard, Benoit ; Leray, Aurélien ; Arzel, Laurence ; Lebreton, Jacques ; Mortier, Erwan ; Dubreuil, Didier ; Mathé-Allainmat, MoniqueBioorganic & medicinal chemistry, 2021-06, Vol.39, p.116161-116161, Article 116161 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
9 |
Material Type: Artigo
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Daphnanes diterpenes from the latex of Hura crepitans L. and their PKCζ-dependent anti-proliferative activity on colorectal cancer cellsCrossay, Elise ; Jullian, Valérie ; Trinel, Manon ; Sagnat, David ; Hamel, Dimitri ; Groppi, Emie ; Rolland, Corinne ; Stigliani, Jean-Luc ; Mejia, Kember ; Cabanillas, Billy Joel ; Alric, Laurent ; Buscail, Etienne ; El Kalamouni, Chaker ; Mavingui, Patrick ; Deraison, Céline ; Racaud-Sultan, Claire ; Fabre, NicolasBioorganic & medicinal chemistry, 2023-07, Vol.90, p.117366-117366, Article 117366 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin KGauthier, Jacques Yves ; Chauret, Nathalie ; Cromlish, Wanda ; Desmarais, Sylvie ; Duong, Le T. ; Falgueyret, Jean-Pierre ; Kimmel, Donald B. ; Lamontagne, Sonia ; Léger, Serge ; LeRiche, Tammy ; Li, Chun Sing ; Massé, Frédéric ; McKay, Daniel J. ; Nicoll-Griffith, Deborah A. ; Oballa, Renata M. ; Palmer, James T. ; Percival, M. David ; Riendeau, Denis ; Robichaud, Joel ; Rodan, Gideon A. ; Rodan, Sevgi B. ; Seto, Carmai ; Thérien, Michel ; Truong, Vouy-Linh ; Venuti, Michael C. ; Wesolowski, Gregg ; Young, Robert N. ; Zamboni, Robert ; Black, W. CameronBioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.923-928 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |