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1 |
Material Type: Artigo
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Ceritinib in ALK-Rearranged Non–Small-Cell Lung CancerShaw, Alice T ; Kim, Dong-Wan ; Mehra, Ranee ; Tan, Daniel S.W ; Felip, Enriqueta ; Chow, Laura Q.M ; Camidge, D. Ross ; Vansteenkiste, Johan ; Sharma, Sunil ; De Pas, Tommaso ; Riely, Gregory J ; Solomon, Benjamin J ; Wolf, Juergen ; Thomas, Michael ; Schuler, Martin ; Liu, Geoffrey ; Santoro, Armando ; Lau, Yvonne Y ; Goldwasser, Meredith ; Boral, Anthony L ; Engelman, Jeffrey AThe New England journal of medicine, 2014-03, Vol.370 (13), p.1189-1197 [Periódico revisado por pares]Waltham, MA: Massachusetts Medical SocietyTexto completo disponível |
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Material Type: Artigo
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Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid TumorsKROP, Ian ; DEMUTH, Tim ; BLACKMAN, Samuel ; WATTERS, James ; LOBODA, Andrey ; PODTELEZHNIKOV, Alexei ; LUNCEFORD, Jared ; CONG CHEN ; GIANNOTTI, Maxine ; HING, Jeremy ; BECKMAN, Robert ; LORUSSO, Patricia ; GUTHRIE, Tina ; WEN, Patrick Y ; MASON, Warren P ; CHINNAIYAN, Prakash ; BUTOWSKI, Nicholas ; GROVES, Morris D ; KESARI, Santosh ; FREEDMAN, Steven JJournal of clinical oncology, 2012-07, Vol.30 (19), p.2307-2313 [Periódico revisado por pares]Alexandria, VA: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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PDE5 inhibition alleviates functional muscle ischemia in boys with Duchenne muscular dystrophyNelson, Michael D ; Rader, Florian ; Tang, Xiu ; Tavyev, Jane ; Nelson, Stanley F ; Miceli, M Carrie ; Elashoff, Robert M ; Sweeney, H Lee ; Victor, Ronald GNeurology, 2014-06, Vol.82 (23), p.2085-2091 [Periódico revisado por pares]Hagerstown, MD: American Academy of NeurologyTexto completo disponível |
4 |
Material Type: Artigo
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Long-term Treatment With Sildenafil Citrate in Pulmonary Arterial Hypertension: The SUPER-2 StudyRUBIN, Lewis J ; BADESCH, David B ; BARST, Robyn J ; FLEMING, Thomas R ; GALIE, Nazzareno ; SIMONNEAU, Gerald ; GHOFRANI, Hossein A ; OAKES, Michael ; LAYTON, Gary ; SERDAREVIC-PEHAR, Marjana ; MCLAUGHLIN, Uallerie VChest, 2011-11, Vol.140 (5), p.1274-1283 [Periódico revisado por pares]Northbrook, IL: American College of Chest PhysiciansTexto completo disponível |
5 |
Material Type: Artigo
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Phase I clinical trial of oral rigosertib in patients with myelodysplastic syndromesKomrokji, Rami S. ; Raza, Azra ; Lancet, Jeffrey E. ; Ren, Chen ; Taft, David ; Maniar, Manoj ; Wilhelm, Francois ; List, Alan F.British journal of haematology, 2013-08, Vol.162 (4), p.517-524 [Periódico revisado por pares]Oxford: BlackwellTexto completo disponível |
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Material Type: Artigo
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Rapid synthesis of sulfone derivatives as potential anti-infectious agentsCurti, C. ; Laget, M. ; Carle, A. Ortiz ; Gellis, A. ; Vanelle, P.European journal of medicinal chemistry, 2007-06, Vol.42 (6), p.880-884 [Periódico revisado por pares]Oxford: Elsevier Masson SASTexto completo disponível |
7 |
Material Type: Artigo
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Phase I Trial of MK-0752 in Children With Refractory CNS Malignancies: A Pediatric Brain Tumor Consortium StudyFOULADI, Maryam ; STEWART, Clinton F ; DEMUTH, Tim ; KUN, Larry E ; BOYETT, James M ; GILBERTSON, Richard J ; OLSON, James ; WAGNER, Lars M ; ONAR-THOMAS, Arzu ; KOCAK, Mehmet ; PACKER, Roger J ; GOLDMAN, Stewart ; GURURANGAN, Sridharan ; GAJJAR, AmarJournal of clinical oncology, 2011-09, Vol.29 (26), p.3529-3534 [Periódico revisado por pares]Alexandria, VA: American Society of Clinical OncologyTexto completo disponível |
8 |
Material Type: Artigo
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Sulfonyl Group-Containing Compounds in the Design of Potential Drugs for the Treatment of Diabetes and Its ComplicationsCHEN, X ; HUSSAIN, S ; PARVEEN, S ; ZHANG, S ; YANG, Y ; ZHU, CCurrent medicinal chemistry, 2012, Vol.19 (21), p.3578-3604 [Periódico revisado por pares]Oak Park, IL: Bentham Science Publishers LtdTexto completo disponível |
9 |
Material Type: Artigo
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Antitrypanosomal Activity of Fexinidazole Metabolites, Potential New Drug Candidates for Chagas DiseaseBAHIA, Maria T ; NASCIMENTO, Alvaro F. S ; KOLTUN, Maria ; SAUNDERS, Jessica ; WHITE, Karen L ; SCANDALE, Ivan ; CHARMAN, Susan A ; CHATELAIN, Eric ; MAZZETI, Ana Lia ; MARQUES, Luiz F ; GONCALVES, Karolina R ; MOTA, Ludmilla W. R ; DINIZ, Lívia de F ; CALDAS, Ivo S ; TALVANI, André ; SHACKLEFORD, David MAntimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4362-4370 [Periódico revisado por pares]Washington, DC: American Society for MicrobiologyTexto completo disponível |
10 |
Material Type: Artigo
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Development of Peptidomimetics with a Vinyl Sulfone Warhead as Irreversible Falcipain-2 InhibitorsEttari, Roberta ; Nizi, Emanuela ; Di Francesco, Maria Emilia ; Dude, Marie-Adrienne ; Pradel, Gabriele ; Vičík, Radim ; Schirmeister, Tanja ; Micale, Nicola ; Grasso, Silvana ; Zappalà, MariaJournal of medicinal chemistry, 2008-02, Vol.51 (4), p.988-996 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |