Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Venneti, Sriram ; Kawakibi, Abed Rahman ; Ji, Sunjong ; Waszak, Sebastian M ; Sweha, Stefan R ; Mota, Mateus ; Pun, Matthew ; Deogharkar, Akash ; Chung, Chan ; Tarapore, Rohinton S ; Ramage, Samuel ; Chi, Andrew ; Wen, Patrick Y ; Arrillaga-Romany, Isabel ; Batchelor, Tracy T ; Butowski, Nicholas A ; Sumrall, Ashley ; Shonka, Nicole ; Harrison, Rebecca A ; de Groot, John ; Mehta, Minesh ; Hall, Matthew D ; Daghistani, Doured ; Cloughesy, Timothy F ; Ellingson, Benjamin M ; Beccaria, Kevin ; Varlet, Pascale ; Kim, Michelle M ; Umemura, Yoshie ; Garton, Hugh ; Franson, Andrea ; Schwartz, Jonathan ; Jain, Rajan ; Kachman, Maureen ; Baum, Heidi ; Burant, Charles F ; Mottl, Sophie L ; Cartaxo, Rodrigo T ; John, Vishal ; Messinger, Dana ; Qin, Tingting ; Peterson, Erik ; Sajjakulnukit, Peter ; Ravi, Karthik ; Waugh, Alyssa ; Walling, Dustin ; Ding, Yujie ; Xia, Ziyun ; Schwendeman, Anna ; Hawes, Debra ; Yang, Fusheng ; Judkins, Alexander R ; Wahl, Daniel ; Lyssiotis, Costas A ; de la Nava, Daniel ; Alonso, Marta M ; Eze, Augustine ; Spitzer, Jasper ; Schmidt, Susanne V ; Duchatel, Ryan J ; Dun, Matthew D ; Cain, Jason E ; Jiang, Li ; Stopka, Sylwia A ; Baquer, Gerard ; Regan, Michael S ; Filbin, Mariella G ; Agar, Nathalie Y R ; Zhao, Lili ; Kumar-Sinha, Chandan ; Mody, Rajen ; Chinnaiyan, Arul ; Kurokawa, Ryo ; Pratt, Drew ; Yadav, Viveka N ; Grill, Jacques ; Kline, Cassie ; Mueller, Sabine ; Resnick, Adam ; Nazarian, Javad ; Allen, Joshua E ; Odia, Yazmin ; Gardner, Sharon L ; Koschmann, Carl

United States: American Association for Cancer Research

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