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Refinado por: Nome da Publicação: Journal Of Medicinal Chemistry remover assunto: Medical Sciences remover
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1
Structure−Activity Relationships at the 5-Position of Thiolactomycin:  An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli
Structure−Activity Relationships at the 5-Position of Thiolactomycin:  An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli
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Structure−Activity Relationships at the 5-Position of Thiolactomycin:  An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli

KIM, Pilho ; ZHANG, Yong-Mei ; SHENOY, Gautham ; NGUYEN, Quynh-Anh ; BOSHOFF, Helena I. ; MANJUNATHA, Ujjini H. ; GOODWIN, Michael B. ; LONSDALE, John ; PRICE, Allen C. ; MILLER, Darcie J. ; DUNCAN, Ken ; WHITE, Stephen W. ; ROCK, Charles O. ; BARRY, Clifton E. ; DOWD, Cynthia S.

Journal of medicinal chemistry, 2006-01, Vol.49 (1), p.159-171 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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2
Rational Design of Novel Immunosuppressive Drugs:  Analogues of Azathioprine Lacking the 6-Mercaptopurine Substituent Retain or Have Enhanced Immunosuppressive Effects
Rational Design of Novel Immunosuppressive Drugs:  Analogues of Azathioprine Lacking the 6-Mercaptopurine Substituent Retain or Have Enhanced Immunosuppressive Effects
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Rational Design of Novel Immunosuppressive Drugs:  Analogues of Azathioprine Lacking the 6-Mercaptopurine Substituent Retain or Have Enhanced Immunosuppressive Effects

Crawford, Duncan J. K ; Maddocks, John L ; Jones, D. Neville ; Szawlowski, Paul

Journal of medicinal chemistry, 1996-07, Vol.39 (14), p.2690-2695 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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3
p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression
p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression
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p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression

Aston, Nicola M ; Bamborough, Paul ; Buckton, Jacqueline B ; Edwards, Christopher D ; Holmes, Duncan S ; Jones, Katherine L ; Patel, Vipulkumar K ; Smee, Penny A ; Somers, Donald O ; Vitulli, Giovanni ; Walker, Ann L

Journal of medicinal chemistry, 2009-10, Vol.52 (20), p.6257-6269 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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4
Synthesis and Biological Activities of (R)-5,6-Dihydro-N,N-dimethyl-4H-imidazo[4,5,1-ij]quinolin-5-amine and Its Metabolites
Synthesis and Biological Activities of (R)-5,6-Dihydro-N,N-dimethyl-4H-imidazo[4,5,1-ij]quinolin-5-amine and Its Metabolites
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Synthesis and Biological Activities of (R)-5,6-Dihydro-N,N-dimethyl-4H-imidazo[4,5,1-ij]quinolin-5-amine and Its Metabolites

Heier, Richard F ; Dolak, Lester A ; Duncan, J. Neil ; Hyslop, Deborah K ; Lipton, Michael F ; Martin, Iain J ; Mauragis, Michael A ; Piercey, Montford F ; Nichols, Nanette F ; Schreur, Peggy J. K. D ; Smith, Martin W ; Moon, Malcolm W

Journal of medicinal chemistry, 1997-02, Vol.40 (5), p.639-646 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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5
Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis
Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis
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Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis

Bramson, H. Neal ; Corona, John ; Davis, Stephen T ; Dickerson, Scott H ; Edelstein, Mark ; Frye, Stephen V ; Gampe, Robert T ; Harris, Phil A ; Hassell, Anne ; Holmes, William D ; Hunter, Robert N ; Lackey, Karen E ; Lovejoy, Brett ; Luzzio, Michael J ; Montana, Val ; Rocque, Warren J ; Rusnak, David ; Shewchuk, Lisa ; Veal, James M ; Walker, Duncan H ; Kuyper, Lee F

Journal of medicinal chemistry, 2001-12, Vol.44 (25), p.4339-4358 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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6
(S)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D4 Antagonist
(S)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D4 Antagonist
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(S)-(−)-4-[4-[2-(Isochroman-1-yl)ethyl]piperazin-1-yl]benzenesulfonamide, a Selective Dopamine D4 Antagonist

TenBrink, Ruth E ; Bergh, Carol L ; Duncan, J. Neil ; Harris, Douglas W ; Huff, R. M ; Lahti, Robert A ; Lawson, Charles F ; Lutzke, Barry S ; Martin, Iain J ; Rees, Susan A ; Schlachter, Siusaidh K ; Sih, John C ; Smith, Martin W

Journal of medicinal chemistry, 1996-06, Vol.39 (13), p.2435-2437 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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7
Dopamine D3 Receptor Antagonists. 1. Synthesis and Structure−Activity Relationships of 5,6-Dimethoxy-N-alkyl- and N-Alkylaryl-Substituted 2-Aminoindans
Dopamine D3 Receptor Antagonists. 1. Synthesis and Structure−Activity Relationships of 5,6-Dimethoxy-N-alkyl- and N-Alkylaryl-Substituted 2-Aminoindans
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Dopamine D3 Receptor Antagonists. 1. Synthesis and Structure−Activity Relationships of 5,6-Dimethoxy-N-alkyl- and N-Alkylaryl-Substituted 2-Aminoindans

Haadsma-Svensson, Susanne R ; Cleek, Kerry A ; Dinh, Dac M ; Duncan, J. Neil ; Haber, Christopher L ; Huff, Rita M ; Lajiness, Mary E ; Nichols, Nanette F ; Smith, Martin W ; Svensson, Kjell A ; Zaya, Matt J ; Carlsson, Arvid ; Lin, Chiu-Hong

Journal of medicinal chemistry, 2001-12, Vol.44 (26), p.4716-4732 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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8
4-[4-[(2-Hydroxybenzoyl)amino]phenyl]butyric Acid as a Novel Oral Delivery Agent for Recombinant Human Growth Hormone
4-[4-[(2-Hydroxybenzoyl)amino]phenyl]butyric Acid as a Novel Oral Delivery Agent for Recombinant Human Growth Hormone
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4-[4-[(2-Hydroxybenzoyl)amino]phenyl]butyric Acid as a Novel Oral Delivery Agent for Recombinant Human Growth Hormone

Leone-Bay, Andrea ; Ho, Koc-Kan ; Agarwal, Rajesh ; Baughman, Robert A ; Chaudhary, Kiran ; DeMorin, Frenel ; Genoble, Lise ; McInnes, Campbell ; Lercara, Christine ; Milstein, Sam ; O'Toole, Doris ; Sarubbi, Donald ; Variano, Bruce ; Paton, Duncan R

Journal of medicinal chemistry, 1996-06, Vol.39 (13), p.2571-2578 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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9
Discovery of 4-[3-(trans-3-Dimethylaminocyclobutyl)-1H-indol-5-ylmethyl]- (4S)-oxazolidin-2-one (4991W93), a 5HT1B/1D Receptor Partial Agonist and a Potent Inhibitor of Electrically Induced Plasma Extravasation
Discovery of 4-[3-(trans-3-Dimethylaminocyclobutyl)-1H-indol-5-ylmethyl]- (4S)-oxazolidin-2-one (4991W93), a 5HT1B/1D Receptor Partial Agonist and a Potent Inhibitor of Electrically Induced Plasma Extravasation
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Discovery of 4-[3-(trans-3-Dimethylaminocyclobutyl)-1H-indol-5-ylmethyl]- (4S)-oxazolidin-2-one (4991W93), a 5HT1B/1D Receptor Partial Agonist and a Potent Inhibitor of Electrically Induced Plasma Extravasation

Jandu, Karamjit Singh ; Barrett, Vikki ; Brockwell, Michael ; Cambridge, David ; Farrant, Duncan R ; Foster, Christopher ; Giles, Heather ; Glen, Robert C ; Hill, Alan P ; Hobbs, Heather ; Honey, Andrew ; Martin, Graeme R ; Salmon, John ; Smith, Donna ; Woollard, Patrick ; Selwood, David L

Journal of medicinal chemistry, 2001-03, Vol.44 (5), p.681-693 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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10
Orally Bioavailable Competitive CCR5 Antagonists
Orally Bioavailable Competitive CCR5 Antagonists
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Orally Bioavailable Competitive CCR5 Antagonists

Thoma, Gebhard ; Nuninger, François ; Schaefer, Marc ; Akyel, Kayhan G ; Albert, Rainer ; Beerli, Christian ; Bruns, Christian ; Francotte, Eric ; Luyten, Marcel ; MacKenzie, Duncan ; Oberer, Lukas ; Streiff, Markus B ; Wagner, Trixie ; Walter, Hansrudolf ; Weckbecker, Gisbert ; Zerwes, Hans-Guenter

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.1939-1955 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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