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Discovery of pyridyl sulfonamide 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors for the treatment of metabolic disorders
Discovery of pyridyl sulfonamide 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors for the treatment of metabolic disorders
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Discovery of pyridyl sulfonamide 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors for the treatment of metabolic disorders

Yoon, David S. ; Wu, Shung C. ; Seethala, Ramakrishna ; Golla, Rajasree ; Nayeem, Akbar ; Everlof, John G. ; Gordon, David A. ; Hamann, Lawrence G. ; Robl, Jeffrey A.

Bioorganic & medicinal chemistry letters, 2014-11, Vol.24 (21), p.5045-5049 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Optimization of cyclic sulfamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury
Optimization of cyclic sulfamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury
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Optimization of cyclic sulfamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitors for the potential treatment of ischemic brain injury

Lee, Jeong Hyun ; Bok, Ju Hwan ; Park, Sung Bum ; Pagire, Haushabhau S. ; Na, Yoon-Ju ; Rim, Eunyoung ; Jung, Won Hoon ; Song, Jin Sook ; Kang, Nam Sook ; Seo, Ho Won ; Jung, Kwan-Young ; Lee, Byung Ho ; Kim, Ki Young ; Ahn, Jin Hee

Bioorganic & medicinal chemistry letters, 2020-01, Vol.30 (2), p.126787-126787, Article 126787 [Periódico revisado por pares]

England: Elsevier Ltd

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3
Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group
Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group
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Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group

Kwon, Sung Wook ; Kang, Seung Kyu ; Lee, Jae Hong ; Bok, Joo Hwan ; Kim, Chi Hyun ; Rhee, Sang Dal ; Jung, Won Hoon ; Kim, Hee Youn ; Bae, Myung Ae ; Song, Jin Sook ; Ha, Duck Chan ; Cheon, Hyae Gyoung ; Kim, Ki Young ; Ahn, Jin Hee

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.435-439 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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4
Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening
Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening
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Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening

Xia, Guangxin ; Xue, Mengzhu ; Liu, Lin ; Yu, Jianxin ; Liu, Haiyan ; Li, Ping ; Wang, Jianfa ; Li, Yanlian ; Xiong, Bing ; Shen, Jingkang

Bioorganic & medicinal chemistry letters, 2011-10, Vol.21 (19), p.5739-5744 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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5
Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1)
Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1)
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Generation of 3,8-substituted 1,2,4-triazolopyridines as potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1)

Wang, Haixia ; Robl, Jeffrey A. ; Hamann, Lawrence G. ; Simpkins, Ligaya ; Golla, Rajasree ; Li, Yi-Xin ; Seethala, Ramakrishna ; Zvyaga, Tatyana ; Gordon, David A. ; Li, James J.

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (14), p.4146-4149 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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6
Mono-carbonyl curcumin analogues as 11β-hydroxysteroid dehydrogenase 1 inhibitors
Mono-carbonyl curcumin analogues as 11β-hydroxysteroid dehydrogenase 1 inhibitors
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Mono-carbonyl curcumin analogues as 11β-hydroxysteroid dehydrogenase 1 inhibitors

Lin, Han ; Hu, Guo-Xin ; Guo, Jingjing ; Ge, Yufei ; Liang, Guang ; Lian, Qing-Quan ; Chu, Yanhui ; Yuan, Xiaohuan ; Huang, Ping ; Ge, Ren-Shan

Bioorganic & medicinal chemistry letters, 2013-08, Vol.23 (15), p.4362-4366 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Discovery and optimization of benzenesulfonanilide derivatives as a novel class of 11β-HSD1 inhibitors
Discovery and optimization of benzenesulfonanilide derivatives as a novel class of 11β-HSD1 inhibitors
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Discovery and optimization of benzenesulfonanilide derivatives as a novel class of 11β-HSD1 inhibitors

Rew, Yosup ; DeGraffenreid, Michael ; He, Xiao ; Jaen, Juan C. ; McMinn, Dustin L. ; Sun, Daqing ; Tu, Hua ; Ursu, Stefania ; Powers, Jay P.

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (11), p.3786-3790 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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8
Adamantane 11-β-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction
Adamantane 11-β-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction
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Adamantane 11-β-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction

Sorensen, Bryan ; Rohde, Jeff ; Wang, Jiahong ; Fung, Steven ; Monzon, Katina ; Chiou, William ; Pan, Liping ; Deng, Xiaoqing ; Stolarik, DeAnne ; Frevert, Ernst U. ; Jacobson, Peer ; Link, J.T.

Bioorganic & medicinal chemistry letters, 2006-12, Vol.16 (23), p.5958-5962 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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9
Synthesis and structure–activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)
Synthesis and structure–activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)
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Synthesis and structure–activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)

Ye, Xiang-Yang ; Yoon, David ; Chen, Stephanie Y. ; Nayeem, Akbar ; Golla, Rajasree ; Seethala, Ramakrishna ; Wang, Mengmeng ; Harper, Timothy ; Sleczka, Bogdan G. ; Apedo, Atsu ; Li, Yi-Xin ; He, Bin ; Kirby, Mark ; Gordon, David A. ; Robl, Jeffrey A.

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (2), p.654-660 [Periódico revisado por pares]

England: Elsevier Ltd

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10
Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome
Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome
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Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome

Maletic, Milana ; Leeman, Aaron ; Szymonifka, Michael ; Mundt, Steven S. ; Zokian, Hratch J. ; Shah, Kashmira ; Dragovic, Jasminka ; Lyons, Kathy ; Thieringer, Rolf ; Vosatka, Anne H. ; Balkovec, James ; Waddell, Sherman T.

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2568-2572 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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