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Molecular design of hypothalamus development
Molecular design of hypothalamus development
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Molecular design of hypothalamus development

Romanov, Roman A ; Tretiakov, Evgenii O ; Kastriti, Maria Eleni ; Zupancic, Maja ; Häring, Martin ; Korchynska, Solomiia ; Popadin, Konstantin ; Benevento, Marco ; Rebernik, Patrick ; Lallemend, Francois ; Nishimori, Katsuhiko ; Clotman, Frédéric ; Andrews, William D ; Parnavelas, John G ; Farlik, Matthias ; Bock, Christoph ; Adameyko, Igor ; Hökfelt, Tomas ; Keimpema, Erik ; Harkany, Tibor

Nature (London), 2020-06, Vol.582 (7811), p.246-252 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Automated design of ligands to polypharmacological profiles
Automated design of ligands to polypharmacological profiles
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Automated design of ligands to polypharmacological profiles

BESNARD, Jeremy ; FILIPPO RUDA, Gian ; SIMEONS, Frederick R. C ; STOJANOVSKI, Laste ; PRAT, Annik ; SEIDAH, Nabil G ; CONSTAM, Daniel B ; RICHARD BICKERTON, G ; READ, Kevin D ; WETSEL, William C ; GILBERT, Ian H ; ROTH, Bryan L ; SETOLA, Vincent ; HOPKINS, Andrew L ; ABECASSIS, Keren ; RODRIGUIZ, Ramona M ; HUANG, Xi-Ping ; NORVAL, Suzanne ; SASSANO, Maria F ; SHIN, Antony I ; WEBSTER, Lauren A

Nature (London), 2012-12, Vol.492 (7428), p.215-220 [Periódico revisado por pares]

London: Nature Publishing Group

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3
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

Dai, Wenhao ; Zhang, Bing ; Jiang, Xia-Ming ; Su, Haixia ; Li, Jian ; Zhao, Yao ; Xie, Xiong ; Jin, Zhenming ; Peng, Jingjing ; Liu, Fengjiang ; Li, Chunpu ; Li, You ; Bai, Fang ; Wang, Haofeng ; Cheng, Xi ; Cen, Xiaobo ; Hu, Shulei ; Yang, Xiuna ; Wang, Jiang ; Liu, Xiang ; Xiao, Gengfu ; Jiang, Hualiang ; Rao, Zihe ; Zhang, Lei-Ke ; Xu, Yechun ; Yang, Haitao ; Liu, Hong

Science (American Association for the Advancement of Science), 2020-06, Vol.368 (6497), p.1331-1335 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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4
Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice
Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice
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Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice

Mourtada, Rida ; Herce, Henry D ; Yin, Daniel J ; Moroco, Jamie A ; Wales, Thomas E ; Engen, John R ; Walensky, Loren D

Nature biotechnology, 2019-10, Vol.37 (10), p.1186-1197 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents
Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents
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Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents

Jan, Muhammad Saeed ; Ahmad, Sajjad ; Hussain, Fida ; Ahmad, Ashfaq ; Mahmood, Fawad ; Rashid, Umer ; Abid, Obaid-ur-Rahman ; Ullah, Farhat ; Ayaz, Muhammad ; Sadiq, Abdul

European journal of medicinal chemistry, 2020-01, Vol.186, p.111863, Article 111863 [Periódico revisado por pares]

France: Elsevier Masson SAS

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6
Defining the Design Principles of Skin Epidermis Postnatal Growth
Defining the Design Principles of Skin Epidermis Postnatal Growth
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Defining the Design Principles of Skin Epidermis Postnatal Growth

Dekoninck, Sophie ; Hannezo, Edouard ; Sifrim, Alejandro ; Miroshnikova, Yekaterina A. ; Aragona, Mariaceleste ; Malfait, Milan ; Gargouri, Souhir ; de Neunheuser, Charlotte ; Dubois, Christine ; Voet, Thierry ; Wickström, Sara A. ; Simons, Benjamin D. ; Blanpain, Cédric

Cell, 2020-04, Vol.181 (3), p.604-620.e22 [Periódico revisado por pares]

United States: Elsevier Inc

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7
Survey of the quality of experimental design, statistical analysis and reporting of research using animals
Survey of the quality of experimental design, statistical analysis and reporting of research using animals
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Survey of the quality of experimental design, statistical analysis and reporting of research using animals

Kilkenny, Carol ; Parsons, Nick ; Kadyszewski, Ed ; Festing, Michael F W ; Cuthill, Innes C ; Fry, Derek ; Hutton, Jane ; Altman, Douglas G McLeod, Malcolm

PloS one, 2009-11, Vol.4 (11), p.e7824-e7824 [Periódico revisado por pares]

United States: Public Library of Science

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8
Single dose streptozotocin-induced diabetes: considerations for study design in islet transplantation models
Single dose streptozotocin-induced diabetes: considerations for study design in islet transplantation models
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Single dose streptozotocin-induced diabetes: considerations for study design in islet transplantation models

Deeds, M.C ; Anderson, J.M ; Armstrong, A.S ; Gastineau, D.A ; Hiddinga, H.J ; Jahangir, A ; Eberhardt, N.L ; Kudva, Y.C

Laboratory Animals, 2011-07, Vol.45 (3), p.131-140 [Periódico revisado por pares]

London, England: SAGE Publications

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9
Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV‑1 Capsid Inhibitors with Improved Antiviral Activities
Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV‑1 Capsid Inhibitors with Improved Antiviral Activities
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Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV‑1 Capsid Inhibitors with Improved Antiviral Activities

Sun, Lin ; Dick, Alexej ; Meuser, Megan E ; Huang, Tianguang ; Zalloum, Waleed A ; Chen, Chin-Ho ; Cherukupalli, Srinivasulu ; Xu, Shujing ; Ding, Xiao ; Gao, Ping ; Kang, Dongwei ; De Clercq, Erik ; Pannecouque, Christophe ; Cocklin, Simon ; Lee, Kuo-Hsiung ; Liu, Xinyong ; Zhan, Peng

Journal of medicinal chemistry, 2020-05, Vol.63 (9), p.4790-4810 [Periódico revisado por pares]

United States: American Chemical Society

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10
Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1–4
Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1–4
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Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1–4

Stewart-Jones, Guillaume B. E. ; Chuang, Gwo-Yu ; Xu, Kai ; Zhou, Tongqing ; Acharya, Priyamvada ; Tsybovsky, Yaroslav ; Ou, Li ; Zhang, Baoshan ; Fernandez-Rodriguez, Blanca ; Gilardi, Valentina ; Silacci-Fregni, Chiara ; Beltramello, Martina ; Baxa, Ulrich ; Druz, Aliaksandr ; Kong, Wing-Pui ; Thomas, Paul V. ; Yang, Yongping ; Foulds, Kathryn E. ; Todd, John-Paul ; Wei, Hui ; Salazar, Andres M. ; Scorpio, Diana G. ; Carragher, Bridget ; Potter, Clinton S. ; Corti, Davide ; Mascola, John R. ; Lanzavecchia, Antonio ; Kwong, Peter D.

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (48), p.12265-12270 [Periódico revisado por pares]

United States: National Academy of Sciences

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