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1
Design, Synthesis, and Evaluation of [18F]BIBD-300 as a Positron Emission Tomography Tracer for Poly(ADP-Ribose) Polymerase‑1
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Design, Synthesis, and Evaluation of [18F]BIBD-300 as a Positron Emission Tomography Tracer for Poly(ADP-Ribose) Polymerase‑1

Zheng, Wei ; Huang, Yong ; Xie, Yi ; Yang, Tingyu ; Cheng, Xuebo ; Chen, Hualong ; Li, Chengze ; Jiang, Zeng ; Yu, Ziyue ; Li, Zhongjing ; Zhang, Lu ; Yuan, Leilei ; Liu, Yajing ; Liang, Ying ; Wu, Zehui

Molecular pharmaceutics, 2024-05, Vol.21 (5), p.2606-2621 [Periódico revisado por pares]

United States: American Chemical Society

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2
Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents
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Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents

Jan, Muhammad Saeed ; Ahmad, Sajjad ; Hussain, Fida ; Ahmad, Ashfaq ; Mahmood, Fawad ; Rashid, Umer ; Abid, Obaid-ur-Rahman ; Ullah, Farhat ; Ayaz, Muhammad ; Sadiq, Abdul

European journal of medicinal chemistry, 2020-01, Vol.186, p.111863, Article 111863 [Periódico revisado por pares]

France: Elsevier Masson SAS

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3
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N‑Myristoyltransferase Inhibitors
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A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N‑Myristoyltransferase Inhibitors

Harrison, Justin R ; Brand, Stephen ; Smith, Victoria ; Robinson, David A ; Thompson, Stephen ; Smith, Alasdair ; Davies, Kenneth ; Mok, Ngai ; Torrie, Leah S ; Collie, Iain ; Hallyburton, Irene ; Norval, Suzanne ; Simeons, Frederick R. C ; Stojanovski, Laste ; Frearson, Julie A ; Brenk, Ruth ; Wyatt, Paul G ; Gilbert, Ian H ; Read, Kevin D

Journal of medicinal chemistry, 2018-09, Vol.61 (18), p.8374-8389 [Periódico revisado por pares]

United States: American Chemical Society

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4
Design, synthesis and biological evaluation of novel 4-alkapolyenylpyrrolo[1,2-a]quinoxalines as antileishmanial agents – Part III
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Design, synthesis and biological evaluation of novel 4-alkapolyenylpyrrolo[1,2-a]quinoxalines as antileishmanial agents – Part III

Ronga, Luisa ; Del Favero, Marco ; Cohen, Anita ; Soum, Claire ; Le Pape, Patrice ; Savrimoutou, Solène ; Pinaud, Noël ; Mullié, Catherine ; Daulouede, Sylvie ; Vincendeau, Philippe ; Farvacques, Natacha ; Agnamey, Patrice ; Pagniez, Fabrice ; Hutter, Sébastien ; Azas, Nadine ; Sonnet, Pascal ; Guillon, Jean

European journal of medicinal chemistry, 2014-06, Vol.81, p.378-393 [Periódico revisado por pares]

France: Elsevier Masson SAS

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5
Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)‑ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors
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Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)‑ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors

Kung, Pei-Pei ; Rui, Eugene ; Bergqvist, Simon ; Bingham, Patrick ; Braganza, John ; Collins, Michael ; Cui, Mei ; Diehl, Wade ; Dinh, Dac ; Fan, Connie ; Fantin, Valeria R ; Gukasyan, Hovhannes J ; Hu, Wenyue ; Huang, Buwen ; Kephart, Susan ; Krivacic, Cody ; Kumpf, Robert A ; Li, Gary ; Maegley, Karen A ; McAlpine, Indrawan ; Nguyen, Lisa ; Ninkovic, Sacha ; Ornelas, Martha ; Ryskin, Michael ; Scales, Stephanie ; Sutton, Scott ; Tatlock, John ; Verhelle, Dominique ; Wang, Fen ; Wells, Peter ; Wythes, Martin ; Yamazaki, Shinji ; Yip, Brian ; Yu, Xiu ; Zehnder, Luke ; Zhang, Wei-Guo ; Rollins, Robert A ; Edwards, Martin

Journal of medicinal chemistry, 2016-09, Vol.59 (18), p.8306-8325 [Periódico revisado por pares]

United States: American Chemical Society

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6
Immunity by formulation design: Induction of high CD8 + T-cell responses by poly(I:C) incorporated into the CAF01 adjuvant via a double emulsion method
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Immunity by formulation design: Induction of high CD8 + T-cell responses by poly(I:C) incorporated into the CAF01 adjuvant via a double emulsion method

Nordly, Pernille ; Rose, Fabrice ; Christensen, Dennis ; Nielsen, Hanne Mørck ; Andersen, Peter ; Agger, Else Marie ; Foged, Camilla

Journal of controlled release, 2011-03, Vol.150 (3), p.307-317 [Periódico revisado por pares]

Kidlington: Elsevier B.V

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7
Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV‑1 Capsid Inhibitors with Improved Antiviral Activities
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Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV‑1 Capsid Inhibitors with Improved Antiviral Activities

Sun, Lin ; Dick, Alexej ; Meuser, Megan E ; Huang, Tianguang ; Zalloum, Waleed A ; Chen, Chin-Ho ; Cherukupalli, Srinivasulu ; Xu, Shujing ; Ding, Xiao ; Gao, Ping ; Kang, Dongwei ; De Clercq, Erik ; Pannecouque, Christophe ; Cocklin, Simon ; Lee, Kuo-Hsiung ; Liu, Xinyong ; Zhan, Peng

Journal of medicinal chemistry, 2020-05, Vol.63 (9), p.4790-4810 [Periódico revisado por pares]

United States: American Chemical Society

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8
Design and Validation of Liposomal ApoE2 Gene Delivery System to Evade Blood–Brain Barrier for Effective Treatment of Alzheimer’s Disease
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Design and Validation of Liposomal ApoE2 Gene Delivery System to Evade Blood–Brain Barrier for Effective Treatment of Alzheimer’s Disease

Arora, Sanjay ; Layek, Buddhadev ; Singh, Jagdish

Molecular pharmaceutics, 2021-02, Vol.18 (2), p.714-725 [Periódico revisado por pares]

United States: American Chemical Society

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9
Design, Synthesis, and Pharmacological Evaluation of N‑Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase‑4 Inhibitors
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Design, Synthesis, and Pharmacological Evaluation of N‑Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally Active Phosphodiesterase‑4 Inhibitors

Kümmerle, Arthur E ; Schmitt, Martine ; Cardozo, Suzana V. S ; Lugnier, Claire ; Villa, Pascal ; Lopes, Alexandra B ; Romeiro, Nelilma C ; Justiniano, Hélène ; Martins, Marco A ; Fraga, Carlos A. M ; Bourguignon, Jean-Jacques ; Barreiro, Eliezer J

Journal of medicinal chemistry, 2012-09, Vol.55 (17), p.7525-7545 [Periódico revisado por pares]

United States: American Chemical Society

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10
Design, Synthesis, Mechanisms of Action, and Toxicity of Novel 20(S)‑Sulfonylamidine Derivatives of Camptothecin as Potent Antitumor Agents
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Design, Synthesis, Mechanisms of Action, and Toxicity of Novel 20(S)‑Sulfonylamidine Derivatives of Camptothecin as Potent Antitumor Agents

Wang, Mei-Juan ; Liu, Ying-Qian ; Chang, Ling-Chu ; Wang, Chih-Ya ; Zhao, Yong-Long ; Zhao, Xiao-Bo ; Qian, Keduo ; Nan, Xiang ; Yang, Liu ; Yang, Xiao-Ming ; Hung, Hsin-Yi ; Yang, Jai-Sing ; Kuo, Daih-Huang ; Goto, Masuo ; Morris-Natschke, Susan L ; Pan, Shiow-Lin ; Teng, Che-Ming ; Kuo, Sheng-Chu ; Wu, Tian-Shung ; Wu, Yang-Chang ; Lee, Kuo-Hsiung

Journal of medicinal chemistry, 2014-07, Vol.57 (14), p.6008-6018 [Periódico revisado por pares]

United States: American Chemical Society

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