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11
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice
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Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice

Franko, Andras ; Huypens, Peter ; Neschen, Susanne ; Irmler, Martin ; Rozman, Jan ; Rathkolb, Birgit ; Neff, Frauke ; Prehn, Cornelia ; Dubois, Guillaume ; Baumann, Martina ; Massinger, Rebecca ; Gradinger, Daniel ; Przemeck, Gerhard K H ; Repp, Birgit ; Aichler, Michaela ; Feuchtinger, Annette ; Schommers, Philipp ; Stöhr, Oliver ; Sanchez-Lasheras, Carmen ; Adamski, Jerzy ; Peter, Andreas ; Prokisch, Holger ; Beckers, Johannes ; Walch, Axel K ; Fuchs, Helmut ; Wolf, Eckhard ; Schubert, Markus ; Wiesner, Rudolf J ; Hrabě de Angelis, Martin

Diabetes (New York, N.Y.), 2016-09, Vol.65 (9), p.2540-2552 [Periódico revisado por pares]

United States: American Diabetes Association

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12
Chronic NOS inhibition accelerates NAFLD progression in an obese rat model
Chronic NOS inhibition accelerates NAFLD progression in an obese rat model
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Chronic NOS inhibition accelerates NAFLD progression in an obese rat model

Sheldon, Ryan D ; Padilla, Jaume ; Jenkins, Nathan T ; Laughlin, M Harold ; Rector, R Scott

American journal of physiology: Gastrointestinal and liver physiology, 2015-03, Vol.308 (6), p.G540-G549 [Periódico revisado por pares]

United States: American Physiological Society

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13
Apoptosis-Inducing Factor Modulates Mitochondrial Oxidant Stress in Acetaminophen Hepatotoxicity
Apoptosis-Inducing Factor Modulates Mitochondrial Oxidant Stress in Acetaminophen Hepatotoxicity
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Apoptosis-Inducing Factor Modulates Mitochondrial Oxidant Stress in Acetaminophen Hepatotoxicity

Bajt, Mary Lynn ; Ramachandran, Anup ; Yan, Hui-Min ; Lebofsky, Margitta ; Farhood, Anwar ; Lemasters, John J ; Jaeschke, Hartmut

Toxicological sciences, 2011-08, Vol.122 (2), p.598-605 [Periódico revisado por pares]

United States: Oxford University Press

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14
Evaluation of the Potential for Drug-Induced Liver Injury Based on in Vitro Covalent Binding to Human Liver Proteins
Evaluation of the Potential for Drug-Induced Liver Injury Based on in Vitro Covalent Binding to Human Liver Proteins
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Evaluation of the Potential for Drug-Induced Liver Injury Based on in Vitro Covalent Binding to Human Liver Proteins

USUI, Toru ; MISE, Masashi ; HASHIZUME, Takanori ; YABUKI, Masashi ; KOMURO, Setsuko

Drug metabolism and disposition, 2009-12, Vol.37 (12), p.2383-2392 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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15
Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice
Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice
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Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice

Kawase, Atsushi ; Mukai, Hideyuki ; Tateishi, Shunsuke ; Kuroda, Shintaro ; Kazaoka, Akira ; Satoh, Ryosuke ; Shimada, Hiroaki ; Sugiura, Reiko ; Iwaki, Masahiro

The Journal of pharmacology and experimental therapeutics, 2021-10, Vol.379 (1), p.53-63 [Periódico revisado por pares]

United States

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16
Troglitazone-Induced Hepatic Necrosis in an Animal Model of Silent Genetic Mitochondrial Abnormalities
Troglitazone-Induced Hepatic Necrosis in an Animal Model of Silent Genetic Mitochondrial Abnormalities
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Troglitazone-Induced Hepatic Necrosis in an Animal Model of Silent Genetic Mitochondrial Abnormalities

Ong, Michie M.K. ; Latchoumycandane, Calivarathan ; Boelsterli, Urs A.

Toxicological sciences, 2007-05, Vol.97 (1), p.205-213 [Periódico revisado por pares]

United States: Oxford University Press

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17
Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance
Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance
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Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance

Strelevitz, Timothy J ; Orozco, Christine C ; Obach, R Scott

Drug metabolism and disposition, 2012-07, Vol.40 (7), p.1441-1448 [Periódico revisado por pares]

United States

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18
Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain
Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain
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Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport Chain

St-Pierre, Julie ; Buckingham, Julie A. ; Roebuck, Stephen J. ; Brand, Martin D.

The Journal of biological chemistry, 2002-11, Vol.277 (47), p.44784-44790 [Periódico revisado por pares]

United States: American Society for Biochemistry and Molecular Biology

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19
In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl- β -D-glucuronide in the Liver
In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl- β -D-glucuronide in the Liver
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In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl- β -D-glucuronide in the Liver

Katsube, Yurie ; Tsujimoto, Masayuki ; Koide, Hiroyoshi ; Hira, Daiki ; Ikeda, Yoshito ; Minegaki, Tetsuya ; Morita, Shin-Ya ; Terada, Tomohiro ; Nishiguchi, Kohshi

Drug metabolism and disposition, 2021-04, Vol.49 (4), p.289-297 [Periódico revisado por pares]

United States

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20
Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
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Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats

Iida, Azumi ; Sasaki, Eita ; Yano, Azusa ; Tsuneyama, Koichi ; Fukami, Tatsuki ; Nakajima, Miki ; Yokoi, Tsuyoshi

Drug metabolism and disposition, 2015-07, Vol.43 (7), p.958 [Periódico revisado por pares]

United States

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