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Material Type: Artigo
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Metabolism and pathways for denitration of organic nitrates in the human liverGovoni, Mirco ; Tocchetti, Paola ; Lundberg, Jon OThe Journal of pharmacology and experimental therapeutics, 2013-07, Vol.346 (1), p.96-104 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by ClomethiazoleStresser, David M ; Perloff, Elke S ; Mason, Andrew K ; Blanchard, Andrew P ; Dehal, Shangara S ; Creegan, Timothy P ; Singh, Ritu ; Gangl, Eric TDrug metabolism and disposition, 2016-08, Vol.44 (8), p.1424-1430 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Regulation of succinate-fuelled mitochondrial respiration in liver and skeletal muscle of hibernating thirteen-lined ground squirrelsBrown, Jason C L ; Chung, Dillon J ; Cooper, Alex N ; Staples, James FJournal of experimental biology, 2013-05, Vol.216 (Pt 9), p.1736-1743 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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Cytochrome P450 1A2 Detoxicates Aristolochic Acid in the MouseROSENQUIST, Thomas A ; EINOLF, Heidi J ; DICKMAN, Kathleen G ; LAI WANG ; SMITH, Amanda ; GROLLMAN, Arthur PDrug metabolism and disposition, 2010-05, Vol.38 (5), p.761-768 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Nicotinamide N-oxidation by CYP2E1 in human liver microsomesReal, Alexander Michael ; Hong, Shangyu ; Pissios, PavlosDrug metabolism and disposition, 2013-03, Vol.41 (3), p.550-553 [Periódico revisado por pares]United States: The American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestineShiraga, Toshifumi ; Yajima, Kanako ; Suzuki, Kenta ; Suzuki, Katsuhiro ; Hashimoto, Tadashi ; Iwatsubo, Takafumi ; Miyashita, Aiji ; Usui, TakashiDrug metabolism and disposition, 2012-02, Vol.40 (2), p.276-282 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytesXing, Jie ; Kirby, Brian J ; Whittington, Dale ; Wan, Yakun ; Goodlett, David RDrug metabolism and disposition, 2012-09, Vol.40 (9), p.1757-1764 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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A Humanized UGT1 Mouse Model Expressing the UGT1A128 Allele for Assessing Drug Clearance by UGT1A1-Dependent GlucuronidationHONGLIANG CAI ; NGUYEN, Nghia ; PETERKIN, Vincent ; YANG, Young-Sun ; HOTZ, Kathy ; BEATON LA PLACA, Deirdre ; SHUJUAN CHEN ; TUKEY, Robert H ; STEVENS, Jeffrey CDrug metabolism and disposition, 2010-05, Vol.38 (5), p.879-886 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Azole Antifungal Inhibition of Buprenorphine, Methadone and Oxycodone In Vitro MetabolismMoody, David E ; Liu, Fenyun ; Fang, Wenfang BJournal of analytical toxicology, 2015-06, Vol.39 (5), p.374-386 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Inhibition of Morphine Metabolism by KetamineXIAOXIN QI ; EVANS, Allan M ; JIPING WANG ; MINERS, John O ; UPTON, Richard N ; MILNE, Robert WDrug metabolism and disposition, 2010-05, Vol.38 (5), p.728-731 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |