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Material Type: Artigo
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Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide CotreatmentHassan, Hozeifa Mohamed ; Guo, Hongli ; Yousef, Bashir Alsiddig ; Guerram, Mounia ; Hamdi, Aida Mejda ; Zhang, Luyong ; Jiang, ZhenzhouAntimicrobial agents and chemotherapy, 2016-09, Vol.60 (9), p.5285-5293 [Periódico revisado por pares]United States: American Society for MicrobiologyTexto completo disponível |
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Topology of Superoxide Production from Different Sites in the Mitochondrial Electron Transport ChainSt-Pierre, Julie ; Buckingham, Julie A. ; Roebuck, Stephen J. ; Brand, Martin D.The Journal of biological chemistry, 2002-11, Vol.277 (47), p.44784-44790 [Periódico revisado por pares]United States: American Society for Biochemistry and Molecular BiologyTexto completo disponível |
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Metabolic Epoxidation Is a Critical Step for the Development of Benzbromarone-Induced HepatotoxicityWang, Hui ; Peng, Ying ; Zhang, Tingjian ; Lan, Qunsheng ; Zhao, Huimin ; Wang, Wenbao ; Zhao, Yufei ; Wang, Xu ; Pang, Jianxin ; Wang, Shaojie ; Zheng, JiangDrug metabolism and disposition, 2017-12, Vol.45 (12), p.1354-1363 [Periódico revisado por pares]United States: American Society for Pharmacology and Experimental Therapeutics, IncTexto completo disponível |
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Material Type: Artigo
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Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in RatsIida, Azumi ; Sasaki, Eita ; Yano, Azusa ; Tsuneyama, Koichi ; Fukami, Tatsuki ; Nakajima, Miki ; Yokoi, TsuyoshiDrug metabolism and disposition, 2015-07, Vol.43 (7), p.958 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Using chimeric mice with humanized livers to predict human drug metabolism and a drug-drug interactionNishimura, Toshihiko ; Nishimura, Toshiko ; Hu, Yajing ; Wu, Manhong ; Pham, Edward ; Suemizu, Hiroshi ; Elazar, Menashe ; Liu, Michael ; Idilman, Ramazan ; Yurdaydin, Cihan ; Angus, Peter ; Stedman, Catherine ; Murphy, Brian ; Glenn, Jeffrey ; Nakamura, Masato ; Nomura, Tatsuji ; Chen, Yuan ; Zheng, Ming ; Fitch, William L ; Peltz, GaryThe Journal of pharmacology and experimental therapeutics, 2013-02, Vol.344 (2), p.388-396 [Periódico revisado por pares]United States: The American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in ratsLindquist, Carine ; Bjørndal, Bodil ; Rossmann, Christine Renate ; Tusubira, Deusdedit ; Svardal, Asbjørn ; Røsland, Gro Vatne ; Tronstad, Karl Johan ; Hallström, Seth ; Berge, Rolf KristianJournal of lipid research, 2017-07, Vol.58 (7), p.1362-1373 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Cytochrome c release from rat liver mitochondria is compromised by increased saturated cardiolipin species induced by sucrose feedingRuiz-Ramírez, Angélica ; Barrios-Maya, Miguel-Angel ; López-Acosta, Ocarol ; Molina-Ortiz, Dora ; El-Hafidi, MohammedAmerican journal of physiology: endocrinology and metabolism, 2015-11, Vol.309 (9), p.E777-E786 [Periódico revisado por pares]United States: American Physiological SocietyTexto completo disponível |
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Material Type: Artigo
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Insulin Enhances the Biogenesis of Nuclear Sterol Regulatory Element-binding Protein (SREBP)-1c by Posttranscriptional Down-regulation of Insig-2A and Its Dissociation from SREBP Cleavage-activating Protein (SCAP)·SREBP-1c ComplexYellaturu, Chandrahasa R. ; Deng, Xiong ; Park, Edwards A. ; Raghow, Rajendra ; Elam, Marshall B.The Journal of biological chemistry, 2009-11, Vol.284 (46), p.31726-31734 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A silybin-phospholipid complex prevents mitochondrial dysfunction in a rodent model of nonalcoholic steatohepatitisServiddio, Gaetano ; Bellanti, Francesco ; Giudetti, Anna Maria ; Gnoni, Gabriele Vincenzo ; Petrella, Antonio ; Tamborra, Rosanna ; Romano, Antonino Davide ; Rollo, Tiziana ; Vendemiale, Gianluigi ; Altomare, EmanueleThe Journal of pharmacology and experimental therapeutics, 2010-03, Vol.332 (3), p.922-932 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen speciesSiegmund, Sören V ; Qian, Ting ; de Minicis, Samuele ; Harvey-White, Judith ; Kunos, George ; Vinod, K.Y ; Hungund, Basalingappa ; Schwabe, Robert FThe FASEB journal, 2007-09, Vol.21 (11), p.2798-2806 [Periódico revisado por pares]United States: The Federation of American Societies for Experimental BiologyTexto completo disponível |