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Metabolic activation of hepatotoxic drug (benzbromarone) induced mitochondrial membrane permeability transition
Metabolic activation of hepatotoxic drug (benzbromarone) induced mitochondrial membrane permeability transition
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Metabolic activation of hepatotoxic drug (benzbromarone) induced mitochondrial membrane permeability transition

Shirakawa, Maho ; Sekine, Shuichi ; Tanaka, Ayaka ; Horie, Toshiharu ; Ito, Kousei

Toxicology and applied pharmacology, 2015-10, Vol.288 (1), p.12-18 [Periódico revisado por pares]

United States: Elsevier Inc

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Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites
Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites
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Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites

Ackerson, Timothy ; Amberg, Alexander ; Atzrodt, Jens ; Arabeyre, Catherine ; Defossa, Elisabeth ; Dorau, Martina ; Dudda, Angela ; Dwyer, Jacquelyn ; Holla, Wolfgang ; Kissner, Thomas ; Kohlmann, Markus ; Kürzel, Ulrich ; Pánczél, József ; Rajanna, Shibani ; Riedel, Jens ; Schmidt, Friedemann ; Wäse, Kerstin ; Weitz, Dietmar ; Derdau, Volker

Journal of biochemical and molecular toxicology, 2019-08, Vol.33 (8), p.e22345-n/a [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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3
Effect of the Combination of Ezetimibe and Simvastatin on Gluconeogenesis and Oxygen Consumption in the Rat Liver
Effect of the Combination of Ezetimibe and Simvastatin on Gluconeogenesis and Oxygen Consumption in the Rat Liver
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Effect of the Combination of Ezetimibe and Simvastatin on Gluconeogenesis and Oxygen Consumption in the Rat Liver

Bracht, Lívia ; Caparroz‐Assef, Silvana Martins ; Bracht, Adelar ; Bersani‐Amado, Ciomar Aparecida

Basic & clinical pharmacology & toxicology, 2016-06, Vol.118 (6), p.415-420 [Periódico revisado por pares]

England: Wiley Subscription Services, Inc

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4
Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury
Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury
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Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury

Bellanti, Francesco ; Mirabella, Lucia ; Mitarotonda, Domenica ; Blonda, Maria ; Tamborra, Rosanna ; Cinnella, Gilda ; Fersini, Alberto ; Ambrosi, Antonio ; Dambrosio, Michele ; Vendemiale, Gianluigi ; Serviddio, Gaetano

Free radical biology & medicine, 2016-07, Vol.96, p.323-333 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Evaluation of in Vitro Mitochondrial Toxicity Assays and Physicochemical Properties for Prediction of Organ Toxicity Using 228 Pharmaceutical Drugs
Evaluation of in Vitro Mitochondrial Toxicity Assays and Physicochemical Properties for Prediction of Organ Toxicity Using 228 Pharmaceutical Drugs
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Evaluation of in Vitro Mitochondrial Toxicity Assays and Physicochemical Properties for Prediction of Organ Toxicity Using 228 Pharmaceutical Drugs

Rana, Payal ; Aleo, Michael D ; Gosink, Mark ; Will, Yvonne

Chemical research in toxicology, 2019-01, Vol.32 (1), p.156-167 [Periódico revisado por pares]

United States: American Chemical Society

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6
Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPARα/δ Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis
Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPARα/δ Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis
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Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPARα/δ Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis

Feng, Zhiqi ; Xiang, Jiehao ; Liu, Hui ; Li, Jiaxin ; Xu, Xiangrui ; Sun, Gang ; Zheng, Runan ; Zhang, Shangran ; Liu, Junlong ; Yang, Shanlin ; Xu, Qinglong ; Wen, Xiaoan ; Yuan, Haoliang ; Sun, Hongbin ; Dai, Liang

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.2571-2592 [Periódico revisado por pares]

United States: American Chemical Society

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7
Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver
Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver
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Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver

Tamai, Yasuyuki ; Chen, Zhen ; Wu, Yue ; Okabe, Jun ; Kobayashi, Yoshinao ; Chiba, Hitoshi ; Hui, Shu-Ping ; Eguchi, Akiko ; Iwasa, Motoh ; Ito, Masaaki ; Takei, Yoshiyuki

Biomedicine & pharmacotherapy, 2021-03, Vol.135, p.111181, Article 111181 [Periódico revisado por pares]

France: Elsevier Masson SAS

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8
Early-life exposure to bisphenol a induces liver injury in rats involvement of mitochondria-mediated apoptosis
Early-life exposure to bisphenol a induces liver injury in rats involvement of mitochondria-mediated apoptosis
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Early-life exposure to bisphenol a induces liver injury in rats involvement of mitochondria-mediated apoptosis

Xia, Wei ; Jiang, Ying ; Li, Yuanyuan ; Wan, Yanjian ; Liu, Juan ; Ma, Yue ; Mao, Zhenxing ; Chang, Huailong ; Li, Gengqi ; Xu, Bing ; Chen, Xi ; Xu, Shunqing Nadal, Angel

PloS one, 2014-02, Vol.9 (2), p.e90443 [Periódico revisado por pares]

United States: Public Library of Science

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9
Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment
Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment
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Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment

Hassan, Hozeifa Mohamed ; Guo, Hongli ; Yousef, Bashir Alsiddig ; Guerram, Mounia ; Hamdi, Aida Mejda ; Zhang, Luyong ; Jiang, Zhenzhou

Antimicrobial agents and chemotherapy, 2016-09, Vol.60 (9), p.5285-5293 [Periódico revisado por pares]

United States: American Society for Microbiology

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10
Effect of Gloriosa superba linn (EEGS) on mPT and monosodium glutamate-induced proliferative disorder using rat model
Effect of Gloriosa superba linn (EEGS) on mPT and monosodium glutamate-induced proliferative disorder using rat model
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Effect of Gloriosa superba linn (EEGS) on mPT and monosodium glutamate-induced proliferative disorder using rat model

Olowofolahan, Adeola Oluwakemi ; Olorunsogo, Olufunso Olabode

Journal of ethnopharmacology, 2021-03, Vol.267, p.113498, Article 113498 [Periódico revisado por pares]

Ireland: Elsevier B.V

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