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The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal diseaseSidman, Richard L ; Li, Jianxue ; Lawrence, Matthew ; Hu, Wenzheng ; Musso, Gary F ; Giordano, Ricardo J ; Cardó-Vila, Marina ; Pasqualini, Renata ; Arap, WadihScience translational medicine, 2015-10, Vol.7 (309), p.309ra165-309ra165 [Periódico revisado por pares]United StatesTexto completo disponível |
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Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2DAHER, Joao Paulo L ; PLETNIKOVA, Olga ; MOORE, Darren J ; BISKUP, Saskia ; MUSSO, Alessandra ; GELLHAAR, Sandra ; GALTER, Dagmar ; TRONCOSO, Juan C ; LEE, Michael K ; DAWSON, Ted M ; DAWSON, Valina LHuman molecular genetics, 2012-06, Vol.21 (11), p.2420-2431 [Periódico revisado por pares]Oxford: Oxford University PressTexto completo disponível |
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Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamilyStafa, Klodjan ; Tsika, Elpida ; Moser, Roger ; Musso, Alessandra ; Glauser, Liliane ; Jones, Amy ; Biskup, Saskia ; Xiong, Yulan ; Bandopadhyay, Rina ; Dawson, Valina L ; Dawson, Ted M ; Moore, Darren JHuman molecular genetics, 2014-04, Vol.23 (8), p.2055-2077 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain MalformationGuo, Long ; Bertola, Débora Romeo ; Takanohashi, Asako ; Saito, Asuka ; Segawa, Yuko ; Yokota, Takanori ; Ishibashi, Satoru ; Nishida, Yoichiro ; Yamamoto, Guilherme Lopes ; Franco, José Francisco da Silva ; Honjo, Rachel Sayuri ; Kim, Chong Ae ; Musso, Camila Manso ; Timmons, Margaret ; Pizzino, Amy ; Taft, Ryan J. ; Lajoie, Bryan ; Knight, Melanie A. ; Fischbeck, Kenneth H. ; Singleton, Andrew B. ; Ferreira, Carlos R. ; Wang, Zheng ; Yan, Li ; Garbern, James Y. ; Simsek-Kiper, Pelin O. ; Ohashi, Hirofumi ; Robey, Pamela G. ; Boyde, Alan ; Matsumoto, Naomichi ; Miyake, Noriko ; Spranger, Jürgen ; Schiffmann, Raphael ; Vanderver, Adeline ; Nishimura, Gen ; Passos-Bueno, Maria Rita dos Santos ; Simons, Cas ; Ishikawa, Kinya ; Ikegawa, ShiroAmerican journal of human genetics, 2019-05, Vol.104 (5), p.925-935 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Behavioural, neural and cardiovascular adaptations in mice lacking the NPY Y1 receptorCostoli, Tania ; Sgoifo, Andrea ; Stilli, Donatella ; Flugge, Gabriele ; Adriani, Walter ; Laviola, Giovanni ; Fuchs, Eberhard ; Pedrazzini, Thierry ; Musso, EzioNeuroscience and biobehavioral reviews, 2005-02, Vol.29 (1), p.113-123 [Periódico revisado por pares]United States: Elsevier LtdTexto completo disponível |
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A Susceptible Mouse Model for Zika Virus InfectionDowall, Stuart D ; Graham, Victoria A ; Rayner, Emma ; Atkinson, Barry ; Hall, Graham ; Watson, Robert J ; Bosworth, Andrew ; Bonney, Laura C ; Kitchen, Samantha ; Hewson, Roger Kading, Rebekah CrockettPLoS neglected tropical diseases, 2016-05, Vol.10 (5), p.e0004658-e0004658 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosisZhang, Kezhong ; Wang, Shiyu ; Malhotra, Jyoti ; Hassler, Justin R ; Back, Sung Hoon ; Wang, Guohui ; Chang, Lin ; Xu, Wenbo ; Miao, Hongzhi ; Leonardi, Roberta ; Chen, Y Eugene ; Jackowski, Suzanne ; Kaufman, Randal JThe EMBO journal, 2011-04, Vol.30 (7), p.1357-1375 [Periódico revisado por pares]Chichester, UK: John Wiley & Sons, LtdTexto completo disponível |
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Material Type: Artigo
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Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench InvestigationKim, Chai-Wan ; Addy, Carol ; Kusunoki, Jun ; Anderson, Norma N. ; Deja, Stanislaw ; Fu, Xiaorong ; Burgess, Shawn C. ; Li, Cai ; Ruddy, Marcie ; Chakravarthy, Manu ; Previs, Steve ; Milstein, Stuart ; Fitzgerald, Kevin ; Kelley, David E. ; Horton, Jay D.Cell metabolism, 2017-08, Vol.26 (2), p.394-406.e6 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Osteoprotegerin Promotes Liver Steatosis by Targeting the ERK-PPAR-γ-CD36 PathwayZhang, Cheng ; Luo, Xiaohe ; Chen, Jianrong ; Zhou, Baoyong ; Yang, Mengliu ; Liu, Rui ; Liu, Dongfang ; Gu, Harvest F ; Zhu, Zhiming ; Zheng, Hongting ; Li, Ling ; Yang, GangyiDiabetes (New York, N.Y.), 2019-10, Vol.68 (10), p.1902-1914 [Periódico revisado por pares]United States: American Diabetes AssociationTexto completo disponível |
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Material Type: Artigo
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Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesityLi, Fei ; Jiang, Changtao ; Krausz, Kristopher W ; Li, Yunfei ; Albert, Istvan ; Hao, Haiping ; Fabre, Kristin M ; Mitchell, James B ; Patterson, Andrew D ; Gonzalez, Frank JNature communications, 2013-01, Vol.4 (1), p.2384-2384, Article 2384 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |