large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

Bramsen, Jesper B ; Laursen, Maria B ; Nielsen, Anne F ; Hansen, Thomas B ; Bus, Claus ; Langkjær, Niels ; Babu, B. Ravindra ; Højland, Torben ; Abramov, Mikhail ; Van Aerschot, Arthur ; Odadzic, Dalibor ; Smicius, Romualdas ; Haas, Jens ; Andree, Cordula ; Barman, Jharna ; Wenska, Malgorzata ; Srivastava, Puneet ; Zhou, Chuanzheng ; Honcharenko, Dmytro ; Hess, Simone ; Müller, Elke ; Bobkov, Georgii V ; Mikhailov, Sergey N ; Fava, Eugenio ; Meyer, Thomas F ; Chattopadhyaya, Jyoti ; Zerial, Marino ; Engels, Joachim W ; Herdewijn, Piet ; Wengel, Jesper ; Kjems, Jørgen

Nucleic acids research, 2009-05, Vol.37 (9), p.2867-2881 [Periódico revisado por pares]

England: Oxford University Press

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