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large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
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large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

Bramsen, Jesper B ; Laursen, Maria B ; Nielsen, Anne F ; Hansen, Thomas B ; Bus, Claus ; Langkjær, Niels ; Babu, B. Ravindra ; Højland, Torben ; Abramov, Mikhail ; Van Aerschot, Arthur ; Odadzic, Dalibor ; Smicius, Romualdas ; Haas, Jens ; Andree, Cordula ; Barman, Jharna ; Wenska, Malgorzata ; Srivastava, Puneet ; Zhou, Chuanzheng ; Honcharenko, Dmytro ; Hess, Simone ; Müller, Elke ; Bobkov, Georgii V ; Mikhailov, Sergey N ; Fava, Eugenio ; Meyer, Thomas F ; Chattopadhyaya, Jyoti ; Zerial, Marino ; Engels, Joachim W ; Herdewijn, Piet ; Wengel, Jesper ; Kjems, Jørgen

Nucleic acids research, 2009-05, Vol.37 (9), p.2867-2881 [Periódico revisado por pares]

England: Oxford University Press

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2
Comparison of the RNase H Cleavage Kinetics and Blood Serum Stability of the North-Conformationally Constrained and 2‘-Alkoxy Modified Oligonucleotides
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Comparison of the RNase H Cleavage Kinetics and Blood Serum Stability of the North-Conformationally Constrained and 2‘-Alkoxy Modified Oligonucleotides

Honcharenko, Dmytro ; Barman, Jharna ; Varghese, Oommen P

Biochemistry (Easton), 2007-05, Vol.46 (19), p.5635-5646 [Periódico revisado por pares]

United States: American Chemical Society

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3
Conformationally-constrained indeno[2,1-c]quinolines--a new class of anti-mycobacterial agents
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Conformationally-constrained indeno[2,1-c]quinolines--a new class of anti-mycobacterial agents

Upadhayaya, Ram Shankar ; Lahore, Santosh V ; Sayyed, Aftab Y ; Dixit, Shailesh S ; Shinde, Popat D ; Chattopadhyaya, Jyoti

Organic & biomolecular chemistry, 2010-01, Vol.8 (9), p.2180-2197 [Periódico revisado por pares]

England

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4
Conformationally Constrained 2‘-N,4‘-C-Ethylene-Bridged Thymidine (Aza-ENA-T):  Synthesis, Structure, Physical, and Biochemical Studies of Aza-ENA-T-Modified Oligonucleotides
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Conformationally Constrained 2‘-N,4‘-C-Ethylene-Bridged Thymidine (Aza-ENA-T):  Synthesis, Structure, Physical, and Biochemical Studies of Aza-ENA-T-Modified Oligonucleotides

Varghese, Oommen P ; Barman, Jharna ; Pathmasiri, Wimal ; Plashkevych, Oleksandr ; Honcharenko, Dmytro ; Chattopadhyaya, Jyoti

Journal of the American Chemical Society, 2006-11, Vol.128 (47), p.15173-15187 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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5
Synthesis and structure of azole-fused indeno[2,1-c]quinolines and their anti-mycobacterial properties
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Synthesis and structure of azole-fused indeno[2,1-c]quinolines and their anti-mycobacterial properties

Upadhayaya, Ram Shankar ; Shinde, Popat D ; Sayyed, Aftab Y ; Kadam, Sandip A ; Bawane, Amit N ; Poddar, Avijit ; Plashkevych, Oleksandr ; Földesi, Andras ; Chattopadhyaya, Jyoti

Organic & biomolecular chemistry, 2010-01, Vol.8 (24), p.5661-5673 [Periódico revisado por pares]

England

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6
High-quality oligo-RNA synthesis using the new 2′-O-TEM protecting group by selectively quenching the addition of p-tolyl vinyl sulphone to exocyclic amino functions
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High-quality oligo-RNA synthesis using the new 2′-O-TEM protecting group by selectively quenching the addition of p-tolyl vinyl sulphone to exocyclic amino functions

Zhou, Chuanzheng ; Pathmasiri, Wimal ; Honcharenko, Dmytro ; Chatterjee, Subhrangsu ; Barman, Jharna ; Chattopadhyaya, Jyoti

Canadian journal of chemistry, 2007-04, Vol.85 (4), p.293-301 [Periódico revisado por pares]

Ottawa, Canada: NRC Research Press

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