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Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia
Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia
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Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia

Furman, Richard R ; Sharman, Jeff P ; Coutre, Steven E ; Cheson, Bruce D ; Pagel, John M ; Hillmen, Peter ; Barrientos, Jacqueline C ; Zelenetz, Andrew D ; Kipps, Thomas J ; Flinn, Ian ; Ghia, Paolo ; Eradat, Herbert ; Ervin, Thomas ; Lamanna, Nicole ; Coiffier, Bertrand ; Pettitt, Andrew R ; Ma, Shuo ; Stilgenbauer, Stephan ; Cramer, Paula ; Aiello, Maria ; Johnson, Dave M ; Miller, Langdon L ; Li, Daniel ; Jahn, Thomas M ; Dansey, Roger D ; Hallek, Michael ; O'Brien, Susan M

The New England journal of medicine, 2014-03, Vol.370 (11), p.997-1007 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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2
Heat Shock Protein 90: Inhibitors in Clinical Trials
Heat Shock Protein 90: Inhibitors in Clinical Trials
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Heat Shock Protein 90: Inhibitors in Clinical Trials

Biamonte, Marco A ; Van de Water, Ryan ; Arndt, Joseph W ; Scannevin, Robert H ; Perret, Daniel ; Lee, Wen-Cherng

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.3-17 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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3
The purines: Potent and versatile small molecule inhibitors and modulators of key biological targets
The purines: Potent and versatile small molecule inhibitors and modulators of key biological targets
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The purines: Potent and versatile small molecule inhibitors and modulators of key biological targets

Legraverend, Michel ; Grierson, David S.

Bioorganic & medicinal chemistry, 2006-06, Vol.14 (12), p.3987-4006 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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4
Idelalisib: First Global Approval
Idelalisib: First Global Approval
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Idelalisib: First Global Approval

Markham, Anthony

Drugs (New York, N.Y.), 2014-09, Vol.74 (14), p.1701-1707 [Periódico revisado por pares]

Cham: Springer International Publishing

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5
Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitors
Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitors
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Design, synthesis and biological evaluation of 6-pyridylmethylaminopurines as CDK inhibitors

Wilson, Stuart C. ; Atrash, Butrus ; Barlow, Clare ; Eccles, Susan ; Fischer, Peter M. ; Hayes, Angela ; Kelland, Lloyd ; Jackson, Wayne ; Jarman, Michael ; Mirza, Amin ; Moreno, Javier ; Nutley, Bernard P. ; Raynaud, Florence I. ; Sheldrake, Peter ; Walton, Mike ; Westwood, Robert ; Whittaker, Steven ; Workman, Paul ; McDonald, Edward

Bioorganic & medicinal chemistry, 2011-11, Vol.19 (22), p.6949-6965 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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6
Structure−Activity Relationship of New Anti-Hepatitis C Virus Agents: Heterobicycle−Coumarin Conjugates
Structure−Activity Relationship of New Anti-Hepatitis C Virus Agents: Heterobicycle−Coumarin Conjugates
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Structure−Activity Relationship of New Anti-Hepatitis C Virus Agents: Heterobicycle−Coumarin Conjugates

Neyts, Johan ; Clercq, Erik De ; Singha, Raghunath ; Chang, Yung Hsiung ; Das, Asish R ; Chakraborty, Subhasish K ; Hong, Shih Ching ; Tsay, Shwu-Chen ; Hsu, Ming-Hua ; Hwu, Jih Ru

Journal of medicinal chemistry, 2009-03, Vol.52 (5), p.1486-1490 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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7
8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes
8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes
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8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes

Eckhardt, Matthias ; Langkopf, Elke ; Mark, Michael ; Tadayyon, Moh ; Thomas, Leo ; Nar, Herbert ; Pfrengle, Waldemar ; Guth, Brian ; Lotz, Ralf ; Sieger, Peter ; Fuchs, Holger ; Himmelsbach, Frank

Journal of medicinal chemistry, 2007-12, Vol.50 (26), p.6450-6453 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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8
Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase
Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase
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Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase

Shih, I-Hung ; Vliegen, Inge ; Peng, Betty ; Yang, Huiling ; Hebner, Christy ; Paeshuyse, Jan ; Pürstinger, Gerhard ; Fenaux, Martijn ; Tian, Yang ; Mabery, Eric ; Qi, Xiaoping ; Bahador, Gina ; Paulson, Matthew ; Lehman, Laura S ; Bondy, Steven ; Tse, Winston ; Reiser, Hans ; Lee, William A ; Schmitz, Uli ; Neyts, Johan ; Zhong, Weidong

Antimicrobial Agents and Chemotherapy, 2011-09, Vol.55 (9), p.4196-4203 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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9
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of Oral Sildenafil Citrate in Treatment-Naive Children With Pulmonary Arterial Hypertension
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of Oral Sildenafil Citrate in Treatment-Naive Children With Pulmonary Arterial Hypertension
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A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of Oral Sildenafil Citrate in Treatment-Naive Children With Pulmonary Arterial Hypertension

BARST, Robyn J ; DUNBAR IVY, D ; WESSEL, David L ; GAITAN, Guillermo ; SZATMARI, Andras ; RUDZINSKI, Andrzej ; GARCIA, Alberto E ; SASTRY, B. K. S ; PULIDO, Tomas ; LAYTON, Gary R ; SERDAREVIC-PEHAR, Marjana

Circulation (New York, N.Y.), 2012-01, Vol.125 (2), p.324-334 [Periódico revisado por pares]

Hagerstown, MD: Lippincott Williams & Wilkins

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10
Impact of Oral Sildenafil on Exercise Performance in Children and Young Adults After the Fontan Operation: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
Impact of Oral Sildenafil on Exercise Performance in Children and Young Adults After the Fontan Operation: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
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Impact of Oral Sildenafil on Exercise Performance in Children and Young Adults After the Fontan Operation: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

GOLDBERG, David J ; FRENCH, Benjamin ; MCBRIDE, Michael G ; MARINO, Bradley S ; MIRARCHI, Nicole ; HANNA, Brian D ; WERNOVSKY, Gil ; PARIDON, Stephen M ; RYCHIK, Jack

Circulation (New York, N.Y.), 2011-03, Vol.123 (11), p.1185-1193 [Periódico revisado por pares]

Hagerstown, MD: Lippincott Williams & Wilkins

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