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1
Antibiotics in early life alter the murine colonic microbiome and adiposity
Antibiotics in early life alter the murine colonic microbiome and adiposity
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Antibiotics in early life alter the murine colonic microbiome and adiposity

CHO, Ilseung ; YAMANISHI, Shingo ; HUILIN LI ; ALEKSEYENKO, Alexander V ; BLASER, Martin J ; COX, Laura ; METHE, Barbara A ; ZAVADIL, Jiri ; LI, Kelvin ; ZHAN GAO ; MAHANA, Douglas ; RAJU, Kartik ; TEITLER, Isabel

Nature (London), 2012-08, Vol.488 (7413), p.621-626 [Periódico revisado por pares]

London: Nature Publishing Group

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2
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Nelson, James F ; Carter, Christy S ; Pahor, Marco ; Frenkel, Krystyna ; Miller, Richard A ; Nadon, Nancy L ; Wilkinson, J. Erby ; Fernandez, Elizabeth ; Javors, Martin A ; Flurkey, Kevin ; Astle, Clinton M ; Sharp, Zelton Dave ; Harrison, David E ; Strong, Randy

Nature (London), 2009-07, Vol.460 (7253), p.392-395 [Periódico revisado por pares]

London: Nature Publishing Group

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3
Automated design of ligands to polypharmacological profiles
Automated design of ligands to polypharmacological profiles
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Automated design of ligands to polypharmacological profiles

BESNARD, Jeremy ; FILIPPO RUDA, Gian ; SIMEONS, Frederick R. C ; STOJANOVSKI, Laste ; PRAT, Annik ; SEIDAH, Nabil G ; CONSTAM, Daniel B ; RICHARD BICKERTON, G ; READ, Kevin D ; WETSEL, William C ; GILBERT, Ian H ; ROTH, Bryan L ; SETOLA, Vincent ; HOPKINS, Andrew L ; ABECASSIS, Keren ; RODRIGUIZ, Ramona M ; HUANG, Xi-Ping ; NORVAL, Suzanne ; SASSANO, Maria F ; SHIN, Antony I ; WEBSTER, Lauren A

Nature (London), 2012-12, Vol.492 (7428), p.215-220 [Periódico revisado por pares]

London: Nature Publishing Group

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4
A genome-wide association study of attempted suicide
A genome-wide association study of attempted suicide
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A genome-wide association study of attempted suicide

WILLOUR, V. L ; SEIFUDDIN, F ; PERLIS, R. H ; LEE, P. H ; HUANG, J ; KELSOE, J. R ; SHILLING, P. D ; RIETSCHEL, M ; NÖTHEN, M ; CICHON, S ; GURLING, H ; PURCELL, S ; MAHON, P. B ; SMOLLER, J. W ; CRADDOCK, N ; DEPAULO, J. R ; SCHULZE, T. G ; MCMAHON, F. J ; ZANDI, P. P ; POTASH, J. B ; JANCIC, D ; PIROOZNIA, M ; STEELE, J ; SCHWEIZER, B ; GOES, F. S ; MONDIMORE, F. M ; MACKINNON, D. F

Molecular psychiatry, 2012-04, Vol.17 (4), p.433-444 [Periódico revisado por pares]

Basingstoke: Nature Publishing Group

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5
Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study
Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study
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Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study

Lawitz, Eric, Prof ; Sulkowski, Mark S, Prof ; Ghalib, Reem, MD ; Rodriguez-Torres, Maribel, MD ; Younossi, Zobair M, Prof ; Corregidor, Ana, MD ; DeJesus, Edwin, MD ; Pearlman, Brian, Prof ; Rabinovitz, Mordechai, Prof ; Gitlin, Norman, MD ; Lim, Joseph K, MD ; Pockros, Paul J, MD ; Scott, John D, MD ; Fevery, Bart, MSc ; Lambrecht, Tom, MSc ; Ouwerkerk-Mahadevan, Sivi, PhD ; Callewaert, Katleen, MSc ; Symonds, William T, PharmD ; Picchio, Gaston, PhD ; Lindsay, Karen L, MD ; Beumont, Maria, MD ; Jacobson, Ira M, Prof

The Lancet (British edition), 2014-11, Vol.384 (9956), p.1756-1765 [Periódico revisado por pares]

Kidlington: Elsevier Ltd

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6
Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial
Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial
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Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial

Lawitz, Eric, Prof ; Poordad, Fred F, Prof ; Pang, Phillip S, MD ; Hyland, Robert H, DPhil ; Ding, Xiao, PhD ; Mo, Hongmei, PhD ; Symonds, William T, PharmD ; McHutchison, John G, MD ; Membreno, Fernando E, MD

The Lancet (British edition), 2014-02, Vol.383 (9916), p.515-523 [Periódico revisado por pares]

Kidlington: Elsevier Ltd

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7
Brivanib in Patients With Advanced Hepatocellular Carcinoma Who Were Intolerant to Sorafenib or for Whom Sorafenib Failed: Results From the Randomized Phase III BRISK-PS Study
Brivanib in Patients With Advanced Hepatocellular Carcinoma Who Were Intolerant to Sorafenib or for Whom Sorafenib Failed: Results From the Randomized Phase III BRISK-PS Study
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Brivanib in Patients With Advanced Hepatocellular Carcinoma Who Were Intolerant to Sorafenib or for Whom Sorafenib Failed: Results From the Randomized Phase III BRISK-PS Study

LLOVET, Josep M ; DECAENS, Thomas ; MATHURIN, Philippe ; FARTOUX, Laetitia ; LIN, Deng-Yn ; BRUIX, Jordi ; POON, Ronnie T ; SHERMAN, Morris ; BLANC, Jean-Frédéric ; FINN, Richard S ; TAK, Won-Young ; YEE CHAO ; RAOUL, Jean-Luc ; EZZEDDINE, Rana ; LIU, David ; WALTERS, Ian ; PARK, Joong-Won ; BOUCHER, Eveline ; KUDO, Masatoshi ; CHANG, Charissa ; KANG, Yoon-Koo ; ASSENAT, Eric ; LIM, Ho-Yeong ; BOIGE, Valerie

Journal of clinical oncology, 2013-10, Vol.31 (28), p.3509-3516 [Periódico revisado por pares]

Alexandria, VA: American Society of Clinical Oncology

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8
Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial
Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial
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Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial

Choopanya, Kachit, MD ; Martin, Michael, Dr ; Suntharasamai, Pravan, MD ; Sangkum, Udomsak, MD ; Mock, Philip A, MAppStats ; Leethochawalit, Manoj, MD ; Chiamwongpaet, Sithisat, MD ; Kitisin, Praphan, MD ; Natrujirote, Pitinan, MD ; Kittimunkong, Somyot, MD ; Chuachoowong, Rutt, MD ; Gvetadze, Roman J, MD ; McNicholl, Janet M, MD ; Paxton, Lynn A, MD ; Curlin, Marcel E, MD ; Hendrix, Craig W, MD ; Vanichseni, Suphak, MD

The Lancet (British edition), 2013-06, Vol.381 (9883), p.2083-2090 [Periódico revisado por pares]

Kidlington: Elsevier Ltd

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9
Randomized Phase II/III Trial Assessing Gemcitabine/Carboplatin and Methotrexate/Carboplatin/Vinblastine in Patients With Advanced Urothelial Cancer Who Are Unfit for Cisplatin-Based Chemotherapy: EORTC Study 30986
Randomized Phase II/III Trial Assessing Gemcitabine/Carboplatin and Methotrexate/Carboplatin/Vinblastine in Patients With Advanced Urothelial Cancer Who Are Unfit for Cisplatin-Based Chemotherapy: EORTC Study 30986
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Randomized Phase II/III Trial Assessing Gemcitabine/Carboplatin and Methotrexate/Carboplatin/Vinblastine in Patients With Advanced Urothelial Cancer Who Are Unfit for Cisplatin-Based Chemotherapy: EORTC Study 30986

DE SANTIS, Maria ; BELLMUNT, Joaquim ; COLLETTE, Sandra ; LORENT, Julie ; DE WIT, Ronald ; SYLVESTER, Richard ; MEAD, Graham ; MARTIJN KERST, J ; LEAHY, Michael ; MAROTO, Pablo ; GIL, Thierry ; MARREAUD, Sandrine ; DAUGAARD, Gedske ; SKONECZNA, Iwona

Journal of clinical oncology, 2012-01, Vol.30 (2), p.191-199 [Periódico revisado por pares]

Alexandria, VA: American Society of Clinical Oncology

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10
A restricted cell population propagates glioblastoma growth after chemotherapy
A restricted cell population propagates glioblastoma growth after chemotherapy
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A restricted cell population propagates glioblastoma growth after chemotherapy

JIAN CHEN ; YANJIAO LI ; YU, Tzong-Shiue ; MCKAY, Renee M ; BURNS, Dennis K ; KERNIE, Steven G ; PARADA, Luis F

Nature (London), 2012-08, Vol.488 (7412), p.522-526 [Periódico revisado por pares]

London: Nature Publishing Group

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