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1
New derivatives from dehydrodieugenol B and its methyl ether displayed high anti-Trypanosoma cruzi activity and cause depolarization of the plasma membrane and collapse the mitochondrial membrane potential
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New derivatives from dehydrodieugenol B and its methyl ether displayed high anti-Trypanosoma cruzi activity and cause depolarization of the plasma membrane and collapse the mitochondrial membrane potential

Galhardo, Thalita S. ; Ueno, Anderson K. ; Costa-Silva, Thaís A. ; Tempone, André G. ; Carvalho, Wagner A. ; Fischmeister, Cedric ; Bruneau, Christian ; Mandelli, Dalmo ; Lago, João Henrique G.

Chemico-biological interactions, 2022-10, Vol.366, p.110129-110129, Article 110129 [Periódico revisado por pares]

Elsevier B.V

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2
Ent-kaurane diterpenes isolated from n-hexane extract of Baccharis sphenophylla by bioactivity-guided fractionation target the acidocalcisomes in Trypanosoma cruzi
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Ent-kaurane diterpenes isolated from n-hexane extract of Baccharis sphenophylla by bioactivity-guided fractionation target the acidocalcisomes in Trypanosoma cruzi

da Costa-Silva, Thais A. ; Silva, Matheus L. ; Antar, Guilherme M. ; Tempone, Andre G. ; Lago, João Henrique G.

Phytomedicine (Stuttgart), 2021-12, Vol.93, p.153748-153748, Article 153748 [Periódico revisado por pares]

Elsevier GmbH

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3
Antiparasitic activity and effect of casearins isolated from Casearia sylvestris on Leishmania and Trypanosoma cruzi plasma membrane
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Antiparasitic activity and effect of casearins isolated from Casearia sylvestris on Leishmania and Trypanosoma cruzi plasma membrane

Bou, Diego Dinis ; Tempone, André G. ; Pinto, Érika G. ; Lago, João Henrique G. ; Sartorelli, Patricia

Phytomedicine (Stuttgart), 2014-04, Vol.21 (5), p.676-681 [Periódico revisado por pares]

Germany: Elsevier GmbH

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4
Therapeutic effect of ursolic acid in experimental visceral leishmaniasis
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Therapeutic effect of ursolic acid in experimental visceral leishmaniasis

Jesus, Jéssica A. ; Fragoso, Thais N. ; Yamamoto, Eduardo S. ; Laurenti, Márcia D. ; Silva, Marcelo S. ; Ferreira, Aurea F. ; Lago, João Henrique G. ; Gomes, Gabriela S. ; Passero, Luiz Felipe D.

International journal for parasitology -- drugs and drug resistance, 2017-04, Vol.7 (1), p.1-11 [Periódico revisado por pares]

Netherlands: Elsevier Ltd

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5
Polygodial, a sesquiterpene isolated from Drimys brasiliensis (Winteraceae), triggers glucocorticoid-like effects on pancreatic β-cells
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Artigo
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Polygodial, a sesquiterpene isolated from Drimys brasiliensis (Winteraceae), triggers glucocorticoid-like effects on pancreatic β-cells

Barrosa, Kaidu H. ; Mecchi, Murilo C. ; Rando, Daniela G. ; Ferreira, Ari José S. ; Sartorelli, Patricia ; Valle, Maíra M.R. ; Bordin, Silvana ; Caperuto, Luciana C. ; Lago, João Henrique G. ; Lellis-Santos, Camilo

Chemico-biological interactions, 2016-10, Vol.258, p.245-256 [Periódico revisado por pares]

Ireland: Elsevier Ireland Ltd

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6
The lipidomic and inflammatory profiles of visceral and subcutaneous adipose tissues are distinctly regulated by the SGLT2 inhibitor empagliflozin in Zucker diabetic fatty rats
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The lipidomic and inflammatory profiles of visceral and subcutaneous adipose tissues are distinctly regulated by the SGLT2 inhibitor empagliflozin in Zucker diabetic fatty rats

Aragón-Herrera, Alana ; Moraña-Fernández, Sandra ; Otero-Santiago, Manuel ; Anido-Varela, Laura ; Campos-Toimil, Manuel ; García-Seara, Javier ; Román, Ana ; Seijas, José ; García-Caballero, Lucía ; Rodríguez, Javier ; Tarazón, Estefanía ; Roselló-Lletí, Esther ; Portolés, Manuel ; Lage, Ricardo ; Gualillo, Oreste ; González-Juanatey, José Ramón ; Feijóo-Bandín, Sandra ; Lago, Francisca

Biomedicine & pharmacotherapy, 2023-05, Vol.161, p.114535-114535, Article 114535 [Periódico revisado por pares]

France: Elsevier Masson SAS

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7
Cannabinoids ameliorate disease progression in a model of multiple sclerosis in mice, acting preferentially through CB1 receptor-mediated anti-inflammatory effects
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Cannabinoids ameliorate disease progression in a model of multiple sclerosis in mice, acting preferentially through CB1 receptor-mediated anti-inflammatory effects

de Lago, Eva ; Moreno-Martet, Miguel ; Cabranes, Ana ; Ramos, José A. ; Fernández-Ruiz, Javier

Neuropharmacology, 2012-06, Vol.62 (7), p.2298-2307 [Periódico revisado por pares]

England: Elsevier Ltd

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8
New dimer and trimer of chalcone derivatives from anti-inflammatory and antinociceptive extracts of Schinopsis brasiliensis roots
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New dimer and trimer of chalcone derivatives from anti-inflammatory and antinociceptive extracts of Schinopsis brasiliensis roots

Moreira, Bruno Oliveira ; Vilar, Vanessa Lima Souza ; de Almeida, Ramine Nascimento Santos ; Morbeck, Lorena Lôbo Brito ; Andrade, Bruno Silva ; Barros, Rafael Gomes Moreno ; Neves, Breno Magalhães ; de Carvalho, Anaildes Lago ; Cruz, Mariluze Peixoto ; Yatsuda, Regiane ; David, Jorge Mauricio

Journal of ethnopharmacology, 2022-05, Vol.289, p.115089-115089, Article 115089 [Periódico revisado por pares]

Ireland: Elsevier B.V

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9
Human recombinant relaxin-2 (serelaxin) regulates the proteome, lipidome, lipid metabolism and inflammatory profile of rat visceral adipose tissue
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Human recombinant relaxin-2 (serelaxin) regulates the proteome, lipidome, lipid metabolism and inflammatory profile of rat visceral adipose tissue

Aragón-Herrera, Alana ; Feijóo-Bandín, Sandra ; Vázquez-Abuín, Xocas ; Anido-Varela, Laura ; Moraña-Fernández, Sandra ; Bravo, Susana B. ; Tarazón, Estefanía ; Roselló-Lletí, Esther ; Portolés, Manuel ; García-Seara, Javier ; Seijas, José ; Rodríguez-Penas, Diego ; Bani, Daniele ; Gualillo, Oreste ; González-Juanatey, José Ramón ; Lago, Francisca

Biochemical pharmacology, 2024-05, Vol.223, p.116157-116157, Article 116157 [Periódico revisado por pares]

England: Elsevier Inc

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10
Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels
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Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels

de Lago, Eva ; Petrosino, Stefania ; Valenti, Marta ; Morera, Enrico ; Ortega-Gutierrez, Silvia ; Fernandez-Ruiz, Javier ; Di Marzo, Vincenzo

Biochemical pharmacology, 2005-08, Vol.70 (3), p.446-452 [Periódico revisado por pares]

New York, NY: Elsevier Inc

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