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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

Cheung, Hiu Wing ; Cowley, Glenn S ; Weir, Barbara A ; Boehm, Jesse S ; Rusin, Scott ; Scott, Justine A ; East, Alexandra ; Ali, Levi D ; Lizotte, Patrick H ; Wong, Terence C ; Jiang, Guozhi ; Hsiao, Jessica ; Mermel, Craig H ; Getz, Gad ; Barretina, Jordi ; Gopal, Shuba ; Tamayo, Pablo ; Gould, Joshua ; Tsherniak, Aviad ; Stransky, Nicolas ; Luo, Biao ; Ren, Yin ; Drapkin, Ronny ; Bhatia, Sangeeta N ; Mesirov, Jill P ; Garraway, Levi A ; Meyerson, Matthew ; Lander, Eric S ; Root, David E ; Hahn, William C

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (30), p.12372-12377 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer
GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer
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GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer

Mourtada-Maarabouni, M ; Pickard, M R ; Hedge, V L ; Farzaneh, F ; Williams, G T

Oncogene, 2009-01, Vol.28 (2), p.195-208 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions
Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions
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Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions

Silvestri, Alessandra ; Palumbo, Francesco ; Rasi, Ignazio ; Posca, Daniela ; Pavlidou, Theodora ; Paoluzi, Serena ; Castagnoli, Luisa ; Cesareni, Giovanni Katoh, Masaru

PloS one, 2015-08, Vol.10 (8), p.e0136250-e0136250 [Periódico revisado por pares]

United States: Public Library of Science

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4
Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid‐mediated mitochondrial pathway
Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid‐mediated mitochondrial pathway
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Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid‐mediated mitochondrial pathway

Hu, Chun ; Song, Gang ; Zhang, Bing ; Liu, Zhongchen ; Chen, Rong ; Zhang, Hong ; Hu, Tianhui

Journal of cellular and molecular medicine, 2012-01, Vol.16 (1), p.96-106 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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5
Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2
Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2
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Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2

Agrawal, Siddarth ; Woźniak, Marta ; Łuc, Mateusz ; Makuch, Sebastian ; Pielka, Ewa ; Agrawal, Anil Kumar ; Wietrzyk, Joanna ; Banach, Joanna ; Gamian, Andrzej ; Pizon, Monika ; Ziółkowski, Piotr

Scientific reports, 2019-11, Vol.9 (1), p.16647-14, Article 16647 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures
Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures
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Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures

Nakano, Tomoyuki ; Kanai, Yoshihiko ; Amano, Yusuke ; Yoshimoto, Taichiro ; Matsubara, Daisuke ; Shibano, Tomoki ; Tamura, Tomoko ; Oguni, Sachiko ; Katashiba, Shizuka ; Ito, Takeshi ; Murakami, Yoshinori ; Fukayama, Masashi ; Murakami, Takashi ; Endo, Shunsuke ; Niki, Toshiro Cordes, Nils

PloS one, 2017-08, Vol.12 (8), p.e0181342-e0181342 [Periódico revisado por pares]

United States: Public Library of Science

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7
Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism
Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism
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Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism

Liao, Jianqun ; Qian, Feng ; Tchabo, Nana ; Mhawech-Fauceglia, Paulette ; Beck, Amy ; Qian, Zikun ; Wang, Xinhui ; Huss, Wendy J ; Lele, Shashikant B ; Morrison, Carl D ; Odunsi, Kunle Orsulic, Sandra

PloS one, 2014-01, Vol.9 (1), p.e84941 [Periódico revisado por pares]

United States: Public Library of Science

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8
Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins
Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins
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Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins

Dorayappan, Kalpana Deepa Priya ; Wanner, Ross ; Wallbillich, John J ; Saini, Uksha ; Zingarelli, Roman ; Suarez, Adrian A ; Cohn, David E ; Selvendiran, Karuppaiyah

Oncogene, 2018-07, Vol.37 (28), p.3806-3821 [Periódico revisado por pares]

England: Nature Publishing Group

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9
TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype
TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype
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TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype

Rahman, Monzur ; Davis, Sean R ; Pumphrey, Janet G ; Bao, Jing ; Nau, Marion M ; Meltzer, Paul S ; Lipkowitz, Stanley

Breast cancer research and treatment, 2009-01, Vol.113 (2), p.217-230 [Periódico revisado por pares]

Boston: Boston : Springer US

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10
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
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Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

Garcia-Bermudez, Javier ; Baudrier, Lou ; Bayraktar, Erol Can ; Shen, Yihui ; La, Konnor ; Guarecuco, Rohiverth ; Yucel, Burcu ; Fiore, Danilo ; Tavora, Bernardo ; Freinkman, Elizaveta ; Chan, Sze Ham ; Lewis, Caroline ; Min, Wei ; Inghirami, Giorgio ; Sabatini, David M ; Birsoy, Kıvanç

Nature (London), 2019-03, Vol.567 (7746), p.118-122 [Periódico revisado por pares]

England: Nature Publishing Group

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