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11 |
Material Type: Artigo
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Telaprevir for Previously Untreated Chronic Hepatitis C Virus InfectionJacobson, Ira M ; McHutchison, John G ; Dusheiko, Geoffrey ; Di Bisceglie, Adrian M ; Reddy, K. Rajender ; Bzowej, Natalie H ; Marcellin, Patrick ; Muir, Andrew J ; Ferenci, Peter ; Flisiak, Robert ; George, Jacob ; George, Shelley ; Rizzetto, Mario ; Shouval, Daniel ; Sola, Ricard ; Terg, Ruben A ; Yoshida, Eric M ; Adda, Nathalie ; Bengtsson, Leif ; Sankoh, Abdul J ; Kieffer, Tara L ; Kauffman, Robert S ; M.D, Stefan ZeuzemThe New England journal of medicine, 2011-06, Vol.364 (25), p.2405-2416 [Periódico revisado por pares]Waltham, MA: Massachusetts Medical SocietyTexto completo disponível |
12 |
Material Type: Artigo
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Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activityPanagos, Charalampos G ; Thomson, Derek S ; Moss, Claire ; Hughes, Adam D ; Kelly, Maeve S ; Liu, Yan ; Chai, Wengang ; Venkatasamy, Radhakrishnan ; Spina, Domenico ; Page, Clive P ; Hogwood, John ; Woods, Robert J ; Mulloy, Barbara ; Bavington, Charlie D ; Uhrín, DušanThe Journal of biological chemistry, 2014-10, Vol.289 (41), p.28284-28298 [Periódico revisado por pares]United States: American Society for Biochemistry and Molecular BiologyTexto completo disponível |
13 |
Material Type: Artigo
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Proteinases and signalling: pathophysiological and therapeutic implications via PARs and moreRamachandran, R ; Hollenberg, M DBritish journal of pharmacology, 2008-03, Vol.153 (S1), p.S263-S282 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
14 |
Material Type: Artigo
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Crystal structure of Aedes aegypti trypsin inhibitor in complex with μ‐plasmin reveals role for scaffold stability in Kazal‐type serine protease inhibitorWalvekar, Varsha Ashok ; Ramesh, Karthik ; Jobichen, Chacko ; Kannan, Muthu ; Sivaraman, J. ; Kini, R. Manjunatha ; Mok, Yu KeungProtein science, 2022-02, Vol.31 (2), p.470-484 [Periódico revisado por pares]Hoboken, USA: John Wiley & Sons, IncTexto completo disponível |
15 |
Material Type: Artigo
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Effector Specialization in a Lineage of the Irish Potato Famine PathogenDong, Suomeng ; Stam, Remco ; Cano, Liliana M. ; Song, Jing ; Sklenar, Jan ; Yoshida, Kentaro ; Bozkurt, Tolga O. ; Oliva, Ricardo ; Liu, Zhenyu ; Tian, Miaoying ; Win, Joe ; Banfield, Mark J. ; Jones, Alexandra M. E. ; van der Hoorn, Renier A. L. ; Kamoun, SophienScience (American Association for the Advancement of Science), 2014-01, Vol.343 (6170), p.552-555 [Periódico revisado por pares]United States: American Association for the Advancement of ScienceTexto completo disponível |
16 |
Material Type: Artigo
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Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) proteinMitchell, Aaron C. ; Kannan, Deepti ; Hunter, Sean A. ; Parra Sperberg, R. Andres ; Chang, Cheryl H. ; Cochran, Jennifer R.The Journal of biological chemistry, 2018-04, Vol.293 (14), p.4969-4980 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
17 |
Material Type: Artigo
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Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitorsSzakács, Dávid ; Kocsis, Andrea ; Szász, Róbert ; Gál, Péter ; Pál, GáborThe Journal of biological chemistry, 2019-05, Vol.294 (20), p.8227-8237 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
18 |
Material Type: Artigo
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Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitorsAdibekian, Alexander ; Martin, Brent R ; Wang, Chu ; Hsu, Ku-Lung ; Bachovchin, Daniel A ; Niessen, Sherry ; Hoover, Heather ; Cravatt, Benjamin FNature chemical biology, 2011-05, Vol.7 (7), p.469-478 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
19 |
Material Type: Artigo
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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virusLamarre, Daniel ; Anderson, Paul C ; Bailey, Murray ; Beaulieu, Pierre ; Bolger, Gordon ; Bonneau, Pierre ; Bös, Michael ; Cameron, Dale R ; Cartier, Mireille ; Cordingley, Michael G ; Faucher, Anne-Marie ; Goudreau, Nathalie ; Kawai, Stephen H ; Kukolj, George ; Lagacé, Lisette ; LaPlante, Steven R ; Narjes, Hans ; Poupart, Marc-André ; Rancourt, Jean ; Sentjens, Roel E ; St George, Roger ; Simoneau, Bruno ; Steinmann, Gerhard ; Thibeault, Diane ; Tsantrizos, Youla S ; Weldon, Steven M ; Yong, Chan-Loi ; Llinàs-Brunet, MontseNature, 2003-11, Vol.426 (6963), p.186-189 [Periódico revisado por pares]London: Nature PublishingTexto completo disponível |
20 |
Material Type: Artigo
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The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucinsMalaker, Stacy A. ; Pedram, Kayvon ; Ferracane, Michael J. ; Bensing, Barbara A. ; Krishnan, Venkatesh ; Pett, Christian ; Yu, Jin ; Woods, Elliot C. ; Kramer, Jessica R. ; Westerlind, Ulrika ; Dorigo, Oliver ; Bertozzi, Carolyn R.Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7278-7287 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |