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1
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2

Drayman, Nir ; DeMarco, Jennifer K ; Jones, Krysten A ; Azizi, Saara-Anne ; Froggatt, Heather M ; Tan, Kemin ; Maltseva, Natalia Ivanovna ; Chen, Siquan ; Nicolaescu, Vlad ; Dvorkin, Steve ; Furlong, Kevin ; Kathayat, Rahul S ; Firpo, Mason R ; Mastrodomenico, Vincent ; Bruce, Emily A ; Schmidt, Madaline M ; Jedrzejczak, Robert ; Muñoz-Alía, Miguel Á ; Schuster, Brooke ; Nair, Vishnu ; Han, Kyu-Yeon ; O'Brien, Amornrat ; Tomatsidou, Anastasia ; Meyer, Bjoern ; Vignuzzi, Marco ; Missiakas, Dominique ; Botten, Jason W ; Brooke, Christopher B ; Lee, Hyun ; Baker, Susan C ; Mounce, Bryan C ; Heaton, Nicholas S ; Severson, William E ; Palmer, Kenneth E ; Dickinson, Bryan C ; Joachimiak, Andrzej ; Randall, Glenn ; Tay, Savaş

Science (American Association for the Advancement of Science), 2021-08, Vol.373 (6557), p.931-936 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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2
Effector Specialization in a Lineage of the Irish Potato Famine Pathogen
Effector Specialization in a Lineage of the Irish Potato Famine Pathogen
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Effector Specialization in a Lineage of the Irish Potato Famine Pathogen

Dong, Suomeng ; Stam, Remco ; Cano, Liliana M. ; Song, Jing ; Sklenar, Jan ; Yoshida, Kentaro ; Bozkurt, Tolga O. ; Oliva, Ricardo ; Liu, Zhenyu ; Tian, Miaoying ; Win, Joe ; Banfield, Mark J. ; Jones, Alexandra M. E. ; van der Hoorn, Renier A. L. ; Kamoun, Sophien

Science (American Association for the Advancement of Science), 2014-01, Vol.343 (6170), p.552-555 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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3
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

Lamarre, Daniel ; Anderson, Paul C ; Bailey, Murray ; Beaulieu, Pierre ; Bolger, Gordon ; Bonneau, Pierre ; Bös, Michael ; Cameron, Dale R ; Cartier, Mireille ; Cordingley, Michael G ; Faucher, Anne-Marie ; Goudreau, Nathalie ; Kawai, Stephen H ; Kukolj, George ; Lagacé, Lisette ; LaPlante, Steven R ; Narjes, Hans ; Poupart, Marc-André ; Rancourt, Jean ; Sentjens, Roel E ; St George, Roger ; Simoneau, Bruno ; Steinmann, Gerhard ; Thibeault, Diane ; Tsantrizos, Youla S ; Weldon, Steven M ; Yong, Chan-Loi ; Llinàs-Brunet, Montse

Nature, 2003-11, Vol.426 (6963), p.186-189 [Periódico revisado por pares]

London: Nature Publishing

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4
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
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Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

Hander Tim ; Fernández-Fernández, Álvaro D ; Kumpf, Robert P ; Willems, Patrick ; Schatowitz Hendrik ; Rombaut Debbie ; Staes An ; Nolf Jonah ; Pottie, Robin ; Yao Panfeng ; Gonçalves, Amanda ; Pavie Benjamin ; Boller, Thomas ; Gevaert Kris ; Frank, Van Breusegem ; Bartels, Sebastian ; Stael Simon

Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6433) [Periódico revisado por pares]

Washington: The American Association for the Advancement of Science

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5
Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes
Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes
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Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes

Sandstrom, Andrew ; Mitchell, Patrick S ; Goers, Lisa ; Mu, Edward W ; Lesser, Cammie F ; Vance, Russell E

Science (American Association for the Advancement of Science), 2019-04, Vol.364 (6435) [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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6
Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion
Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion
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Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion

Nasamu, Armiyaw S. ; Glushakova, Svetlana ; Russo, Ilaria ; Vaupel, Barbara ; Oksman, Anna ; Kim, Arthur S. ; Fremont, Daved H. ; Tolia, Niraj ; Beck, Josh R. ; Meyers, Marvin J. ; Niles, Jacquin C. ; Zimmerberg, Joshua ; Goldberg, Daniel E.

Science (American Association for the Advancement of Science), 2017-10, Vol.358 (6362), p.518-522 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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7
A mitotic stopwatch determines cell fate
A mitotic stopwatch determines cell fate
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A mitotic stopwatch determines cell fate

Bertolin, Agustina P ; Gottifredi, Vanesa

Science (American Association for the Advancement of Science), 2024-03, Vol.383 (6690), p.1414-1415 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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8
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
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Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

Zhang, Linlin ; Lin, Daizong ; Sun, Xinyuanyuan ; Curth, Ute ; Drosten, Christian ; Sauerhering, Lucie ; Becker, Stephan ; Rox, Katharina ; Hilgenfeld, Rolf

Science (American Association for the Advancement of Science), 2020-04, Vol.368 (6489), p.409-412 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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9
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

Dai, Wenhao ; Zhang, Bing ; Jiang, Xia-Ming ; Su, Haixia ; Li, Jian ; Zhao, Yao ; Xie, Xiong ; Jin, Zhenming ; Peng, Jingjing ; Liu, Fengjiang ; Li, Chunpu ; Li, You ; Bai, Fang ; Wang, Haofeng ; Cheng, Xi ; Cen, Xiaobo ; Hu, Shulei ; Yang, Xiuna ; Wang, Jiang ; Liu, Xiang ; Xiao, Gengfu ; Jiang, Hualiang ; Rao, Zihe ; Zhang, Lei-Ke ; Xu, Yechun ; Yang, Haitao ; Liu, Hong

Science (American Association for the Advancement of Science), 2020-06, Vol.368 (6497), p.1331-1335 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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10
Neuropilin-1 is a host factor for SARS-CoV-2 infection
Neuropilin-1 is a host factor for SARS-CoV-2 infection
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Neuropilin-1 is a host factor for SARS-CoV-2 infection

Daly, James L ; Simonetti, Boris ; Klein, Katja ; Chen, Kai-En ; Williamson, Maia Kavanagh ; Antón-Plágaro, Carlos ; Shoemark, Deborah K ; Simón-Gracia, Lorena ; Bauer, Michael ; Hollandi, Reka ; Greber, Urs F ; Horvath, Peter ; Sessions, Richard B ; Helenius, Ari ; Hiscox, Julian A ; Teesalu, Tambet ; Matthews, David A ; Davidson, Andrew D ; Collins, Brett M ; Cullen, Peter J ; Yamauchi, Yohei

Science (American Association for the Advancement of Science), 2020-11, Vol.370 (6518), p.861-865 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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