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In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
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In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells

Montoya, Justin J ; Turnidge, Megan A ; Wai, Daniel H ; Patel, Apurvi R ; Lee, David W ; Gokhale, Vijay ; Hurley, Laurence H ; Arceci, Robert J ; Wetmore, Cynthia ; Azorsa, David O

BMC cancer, 2019-12, Vol.19 (1), p.1251-1251, Article 1251 [Periódico revisado por pares]

England: BioMed Central

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2
The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif
The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif
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The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif

Lukacik, Petra ; Owen, C David ; Harris, Gemma ; Bolla, Jani Reddy ; Picaud, Sarah ; Alibay, Irfan ; Nettleship, Joanne E ; Bird, Louise E ; Owens, Raymond J ; Biggin, Philip C ; Filippakopoulos, Panagis ; Robinson, Carol V ; Walsh, Martin A Pastore, Annalisa

PloS one, 2021-10, Vol.16 (10), p.e0256070 [Periódico revisado por pares]

United States: Public Library of Science

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3
Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression
Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression
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Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression

Bursch, Karina L. ; Goetz, Christopher J. ; Jiao, Guanming ; Nuñez, Raymundo ; Olp, Michael D. ; Dhiman, Alisha ; Khurana, Mallika ; Zimmermann, Michael T. ; Urrutia, Raul A. ; Dykhuizen, Emily C. ; Smith, Brian C.

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107146-107146, Article 107146 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Bromodomain-containing Protein 4 (BRD4) Regulates RNA Polymerase II Serine 2 Phosphorylation in Human CD4+ T Cells
Bromodomain-containing Protein 4 (BRD4) Regulates RNA Polymerase II Serine 2 Phosphorylation in Human CD4+ T Cells
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Bromodomain-containing Protein 4 (BRD4) Regulates RNA Polymerase II Serine 2 Phosphorylation in Human CD4+ T Cells

Zhang, Weishi ; Prakash, Celine ; Sum, Calvin ; Gong, Yue ; Li, Yinghui ; Kwok, Jeffrey J.T. ; Thiessen, Nina ; Pettersson, Sven ; Jones, Steven J.M. ; Knapp, Stefan ; Yang, Henry ; Chin, Keh-Chuang

The Journal of biological chemistry, 2012-12, Vol.287 (51), p.43137-43155 [Periódico revisado por pares]

United States: Elsevier Inc

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5
The role of TLR2, TLR4 and CD14 genetic polymorphisms in gastric carcinogenesis: a case-control study and meta-analysis
The role of TLR2, TLR4 and CD14 genetic polymorphisms in gastric carcinogenesis: a case-control study and meta-analysis
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The role of TLR2, TLR4 and CD14 genetic polymorphisms in gastric carcinogenesis: a case-control study and meta-analysis

Castaño-Rodríguez, Natalia ; Kaakoush, Nadeem O ; Goh, Khean-Lee ; Fock, Kwong Ming ; Mitchell, Hazel M Ojcius, David M.

PloS one, 2013-04, Vol.8 (4), p.e60327 [Periódico revisado por pares]

United States: Public Library of Science

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6
Peopling of the Americas as inferred from ancient genomics
Peopling of the Americas as inferred from ancient genomics
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Peopling of the Americas as inferred from ancient genomics

Willerslev, Eske ; Meltzer, David J

Nature (London), 2021-06, Vol.594 (7863), p.356-364 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Including multiracial individuals is crucial for race, ethnicity and ancestry frameworks in genetics and genomics
Including multiracial individuals is crucial for race, ethnicity and ancestry frameworks in genetics and genomics
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Including multiracial individuals is crucial for race, ethnicity and ancestry frameworks in genetics and genomics

Martschenko, Daphne O ; Wand, Hannah ; Young, Jennifer L ; Wojcik, Genevieve L

Nature genetics, 2023-06, Vol.55 (6), p.895-900 [Periódico revisado por pares]

United States: Nature Publishing Group

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8
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins
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Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins

Zhong, Nan ; Loppnau, Peter ; Seitova, Alma ; Ravichandran, Mani ; Fenner, Maria ; Jain, Harshika ; Bhattacharya, Anandi ; Hutchinson, Ashley ; Paduch, Marcin ; Lu, Vincent ; Olszewski, Michal ; Kossiakoff, Anthony A ; Dowdell, Evan ; Koide, Akiko ; Koide, Shohei ; Huang, Haiming ; Nadeem, Vincent ; Sidhu, Sachdev S ; Greenblatt, Jack F ; Marcon, Edyta ; Arrowsmith, Cheryl H ; Edwards, Aled M ; Gräslund, Susanne Muyldermans, Serge

PloS one, 2015-10, Vol.10 (10), p.e0139695-e0139695 [Periódico revisado por pares]

United States: Public Library of Science

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9
Host-Interactive Genes in Amerindian Helicobacter pylori Diverge from Their Old World Homologs and Mediate Inflammatory Responses
Host-Interactive Genes in Amerindian Helicobacter pylori Diverge from Their Old World Homologs and Mediate Inflammatory Responses
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Host-Interactive Genes in Amerindian Helicobacter pylori Diverge from Their Old World Homologs and Mediate Inflammatory Responses

MANE, S. P ; DOMINGUEZ-BELLO, M. G ; SHALLOM, S ; SHUKLA, M ; VARON, C ; MEGRAUD, F ; MALDONADO-CONTRERAS, A. L ; WILLIAMS, K. P ; BASSAGANYA-RIERA, J ; BLASER, M. J ; SOBRAL, B. W ; HONTECILLAS, R ; SKONECZKA, J ; MOHAPATRA, S. K ; CRASTA, O. R ; EVANS, C ; MODISE, T

Journal of Bacteriology, 2010-06, Vol.192 (12), p.3078-3092 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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10
BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors
BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors
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BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors

Rhyasen, Garrett W ; Yao, Yi ; Zhang, Jingwen ; Dulak, Austin ; Castriotta, Lillian ; Jacques, Kelly ; Zhao, Wei ; Gharahdaghi, Farzin ; Hattersley, Maureen M ; Lyne, Paul D ; Clark, Edwin ; Zinda, Michael ; Fawell, Stephen E ; Mills, Gordon B ; Chen, Huawei Asselin, Eric

PloS one, 2018-07, Vol.13 (7), p.e0200826 [Periódico revisado por pares]

United States: Public Library of Science

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