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1
Species-specific activity of antibacterial drug combinations
Species-specific activity of antibacterial drug combinations
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Species-specific activity of antibacterial drug combinations

Brochado, Ana Rita ; Telzerow, Anja ; Bobonis, Jacob ; Banzhaf, Manuel ; Mateus, André ; Selkrig, Joel ; Huth, Emily ; Bassler, Stefan ; Zamarreño Beas, Jordi ; Zietek, Matylda ; Ng, Natalie ; Foerster, Sunniva ; Ezraty, Benjamin ; Py, Béatrice ; Barras, Frédéric ; Savitski, Mikhail M ; Bork, Peer ; Göttig, Stephan ; Typas, Athanasios

Nature (London), 2018-07, Vol.559 (7713), p.259-263 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Riva, Laura ; Yuan, Shuofeng ; Yin, Xin ; Martin-Sancho, Laura ; Matsunaga, Naoko ; Pache, Lars ; Burgstaller-Muehlbacher, Sebastian ; De Jesus, Paul D ; Teriete, Peter ; Hull, Mitchell V ; Chang, Max W ; Chan, Jasper Fuk-Woo ; Cao, Jianli ; Poon, Vincent Kwok-Man ; Herbert, Kristina M ; Cheng, Kuoyuan ; Nguyen, Tu-Trinh H ; Rubanov, Andrey ; Pu, Yuan ; Nguyen, Courtney ; Choi, Angela ; Rathnasinghe, Raveen ; Schotsaert, Michael ; Miorin, Lisa ; Dejosez, Marion ; Zwaka, Thomas P ; Sit, Ko-Yung ; Martinez-Sobrido, Luis ; Liu, Wen-Chun ; White, Kris M ; Chapman, Mackenzie E ; Lendy, Emma K ; Glynne, Richard J ; Albrecht, Randy ; Ruppin, Eytan ; Mesecar, Andrew D ; Johnson, Jeffrey R ; Benner, Christopher ; Sun, Ren ; Schultz, Peter G ; Su, Andrew I ; García-Sastre, Adolfo ; Chatterjee, Arnab K ; Yuen, Kwok-Yung ; Chanda, Sumit K

Nature (London), 2020-10, Vol.586 (7827), p.113-119 [Periódico revisado por pares]

England: Nature Publishing Group

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3
An analysis of the attrition of drug candidates from four major pharmaceutical companies
An analysis of the attrition of drug candidates from four major pharmaceutical companies
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An analysis of the attrition of drug candidates from four major pharmaceutical companies

Waring, Michael J ; Arrowsmith, John ; Leach, Andrew R ; Leeson, Paul D ; Mandrell, Sam ; Owen, Robert M ; Pairaudeau, Garry ; Pennie, William D ; Pickett, Stephen D ; Wang, Jibo ; Wallace, Owen ; Weir, Alex

Nature reviews. Drug discovery, 2015-07, Vol.14 (7), p.475-486 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

Shu, Shaokun ; Lin, Charles Y ; He, Housheng Hansen ; Witwicki, Robert M ; Tabassum, Doris P ; Roberts, Justin M ; Janiszewska, Michalina ; Huh, Sung Jin ; Liang, Yi ; Ryan, Jeremy ; Doherty, Ernest ; Mohammed, Hisham ; Guo, Hao ; Stover, Daniel G ; Ekram, Muhammad B ; Brown, Jonathan ; D'Santos, Clive ; Krop, Ian E ; Dillon, Deborah ; McKeown, Michael ; Ott, Christopher ; Qi, Jun ; Ni, Min ; Rao, Prakash K ; Duarte, Melissa ; Wu, Shwu-Yuan ; Chiang, Cheng-Ming ; Anders, Lars ; Young, Richard A ; Winer, Eric ; Letai, Antony ; Barry, William T ; Carroll, Jason S ; Long, Henry ; Brown, Myles ; Liu, X Shirley ; Meyer, Clifford A ; Bradner, James E ; Polyak, Kornelia

Nature (London), 2016-01, Vol.529 (7586), p.413-417 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Therapy-induced tumour secretomes promote resistance and tumour progression
Therapy-induced tumour secretomes promote resistance and tumour progression
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Therapy-induced tumour secretomes promote resistance and tumour progression

Obenauf, Anna C ; Zou, Yilong ; Ji, Andrew L ; Vanharanta, Sakari ; Shu, Weiping ; Shi, Hubing ; Kong, Xiangju ; Bosenberg, Marcus C ; Wiesner, Thomas ; Rosen, Neal ; Lo, Roger S ; Massagué, Joan

Nature (London), 2015-04, Vol.520 (7547), p.368-372 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
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Identification of SARS-CoV-2 inhibitors using lung and colonic organoids

Han, Yuling ; Duan, Xiaohua ; Yang, Liuliu ; Nilsson-Payant, Benjamin E ; Wang, Pengfei ; Duan, Fuyu ; Tang, Xuming ; Yaron, Tomer M ; Zhang, Tuo ; Uhl, Skyler ; Bram, Yaron ; Richardson, Chanel ; Zhu, Jiajun ; Zhao, Zeping ; Redmond, David ; Houghton, Sean ; Nguyen, Duc-Huy T ; Xu, Dong ; Wang, Xing ; Jessurun, Jose ; Borczuk, Alain ; Huang, Yaoxing ; Johnson, Jared L ; Liu, Yuru ; Xiang, Jenny ; Wang, Hui ; Cantley, Lewis C ; tenOever, Benjamin R ; Ho, David D ; Pan, Fong Cheng ; Evans, Todd ; Chen, Huanhuan Joyce ; Schwartz, Robert E ; Chen, Shuibing

Nature (London), 2021-01, Vol.589 (7841), p.270-275 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
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Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

Li, Guangdi ; De Clercq, Erik

Nature reviews. Drug discovery, 2020-03, Vol.19 (3), p.149-150 [Periódico revisado por pares]

England: Nature Publishing Group

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8
A critical dose of doxorubicin is required to alter the gene expression profiles in MCF-7 cells acquiring multidrug resistance
A critical dose of doxorubicin is required to alter the gene expression profiles in MCF-7 cells acquiring multidrug resistance
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A critical dose of doxorubicin is required to alter the gene expression profiles in MCF-7 cells acquiring multidrug resistance

Tsou, Shang-Hsun ; Chen, Tzer-Ming ; Hsiao, Hui-Ting ; Chen, Yen-Hui Lee, Jung Weon

PloS one, 2015-01, Vol.10 (1), p.e0116747-e0116747 [Periódico revisado por pares]

United States: Public Library of Science

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9
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors
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Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors

Jia, Yong ; Yun, Cai-Hong ; Park, Eunyoung ; Ercan, Dalia ; Manuia, Mari ; Juarez, Jose ; Xu, Chunxiao ; Rhee, Kevin ; Chen, Ting ; Zhang, Haikuo ; Palakurthi, Sangeetha ; Jang, Jaebong ; Lelais, Gerald ; DiDonato, Michael ; Bursulaya, Badry ; Michellys, Pierre-Yves ; Epple, Robert ; Marsilje, Thomas H ; McNeill, Matthew ; Lu, Wenshuo ; Harris, Jennifer ; Bender, Steven ; Wong, Kwok-Kin ; Jänne, Pasi A ; Eck, Michael J

Nature (London), 2016-06, Vol.534 (7605), p.129-132 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Liver X receptors in lipid metabolism: opportunities for drug discovery
Liver X receptors in lipid metabolism: opportunities for drug discovery
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Liver X receptors in lipid metabolism: opportunities for drug discovery

Hong, Cynthia ; Tontonoz, Peter

Nature reviews. Drug discovery, 2014-06, Vol.13 (6), p.433-444 [Periódico revisado por pares]

England: Nature Publishing Group

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