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Refinado por: Base de dados/Biblioteca: EBSCO_MEDLINE Complete（医学期刊全文数据库） remover Nome da Publicação: Oncogene remover
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Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies
Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies
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Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies

Sebti, S M ; Hamilton, A D

Oncogene, 2000-12, Vol.19 (56), p.6584-6593 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts
Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts
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Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts

SUN, J ; YIMIN QIAN ; HAMILTON, A. D ; SEBTI, S. M

Oncogene, 1998-03, Vol.16 (11), p.1467-1473 [Periódico revisado por pares]

Basingstoke: Nature Publishing

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3
Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines
Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines
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Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines

LERNER, E. C ; ZHANG, T.-T ; KNOWLES, D. B ; QIAN, Y ; HAMILTON, A. D ; SEBTI, S. M

Oncogene, 1997-09, Vol.15 (11), p.1283-1288 [Periódico revisado por pares]

Basingstoke: Nature Publishing

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4
Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter
Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter
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Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter

DELARUE, F. L ; ADNANE, J ; CHELLAPPAN, S ; SEBTI, S. M ; JOSHI, B ; BLASKOVICH, M. A ; WANG, D.-A ; HAWKER, J ; BIZOUARN, F ; OHKANDA, J ; ZHU, K ; HAMILTON, A. D

Oncogene, 2007-02, Vol.26 (5), p.633-640 [Periódico revisado por pares]

Basingstoke: Nature Publishing

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5
Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors
Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors
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Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors

JIAZHI SUN ; WANG, De-An ; SEBTI, Saïd M ; JAIN, Rishi K ; CARIE, Adam ; PAQUETTE, Steve ; ENNIS, Eileen ; BLASKOVICH, Michelle A ; BALDINI, Laura ; COPPOLA, Domenico ; HAMILTON, Andrew D

Oncogene, 2005-07, Vol.24 (29), p.4701-4709 [Periódico revisado por pares]

Basingstoke: Nature Publishing

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6
Design of growth factor antagonists with antiangiogenic and antitumor properties
Design of growth factor antagonists with antiangiogenic and antitumor properties
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Design of growth factor antagonists with antiangiogenic and antitumor properties

Sebti, S M ; Hamilton, A D

Oncogene, 2000-12, Vol.19 (56), p.6566-6573 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf
Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf
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Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf

ZHONGQIU ZHANG ; YIAN WANG ; LANTRY, Laura E ; KASTENS, Elizabeth ; GONGJIE LIU ; HAMILTON, Andrew D ; SEBTI, Said M ; LUBET, Ronald A ; MING YOU

Oncogene, 2003-09, Vol.22 (40), p.6257-6265 [Periódico revisado por pares]

Basingstoke: Nature Publishing

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8
Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ
Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ
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Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ

ADNANE, Jalila ; BIZOUARN, Francisco A ; ZHI CHEN ; OHKANDA, Junko ; HAMILTON, Andrew D ; MUNOZ-ANTONIA, Teresita ; SEBTI, Saïd M

Oncogene, 2000-11, Vol.19 (48), p.5525-5533 [Periódico revisado por pares]

Basingstoke: Nature Publishing

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9
Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter
Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter
Material Type:
Artigo 		Adicionar ao Meu Espaço

Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter

Delarue, F L ; Adnane, J ; Joshi, B ; Blaskovich, M A ; Wang, D-A ; Hawker, J ; Bizouarn, F ; Ohkanda, J ; Zhu, K ; Hamilton, A D ; Chellappan, S ; Sebti, S M

Oncogene, 2007-01, Vol.26 (5), p.633-640 [Periódico revisado por pares]

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10
Identification of a zinc-finger gene at 6q25 : a chromosomal region implicated in development of many solid tumors
Identification of a zinc-finger gene at 6q25 : a chromosomal region implicated in development of many solid tumors
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Identification of a zinc-finger gene at 6q25 : a chromosomal region implicated in development of many solid tumors

ABDOLLAHI, A ; ROBERTS, D ; GODWIN, A. K ; SCHULTZ, D. C ; SONODA, G ; TESTA, J. R ; HAMILTON, T. C

Oncogene, 1997-04, Vol.14 (16), p.1973-1979 [Periódico revisado por pares]

Basingstoke: Nature Publishing

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