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Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
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Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D

Viñuela, Ana ; Varshney, Arushi ; van de Bunt, Martijn ; Prasad, Rashmi B ; Asplund, Olof ; Bennett, Amanda ; Boehnke, Michael ; Brown, Andrew A ; Erdos, Michael R ; Fadista, João ; Hansson, Ola ; Hatem, Gad ; Howald, Cédric ; Iyengar, Apoorva K ; Johnson, Paul ; Krus, Ulrika ; MacDonald, Patrick E ; Mahajan, Anubha ; Manning Fox, Jocelyn E ; Narisu, Narisu ; Nylander, Vibe ; Orchard, Peter ; Oskolkov, Nikolay ; Panousis, Nikolaos I ; Payne, Anthony ; Stitzel, Michael L ; Vadlamudi, Swarooparani ; Welch, Ryan ; Collins, Francis S ; Mohlke, Karen L ; Gloyn, Anna L ; Scott, Laura J ; Dermitzakis, Emmanouil T ; Groop, Leif ; Parker, Stephen C J ; McCarthy, Mark I

Nature communications, 2020-09, Vol.11 (1), p.4912-4912, Article 4912 [Periódico revisado por pares]

England: Nature Publishing Group

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2
A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells
A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells
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A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells

Ye, Yingying ; Barghouth, Mohammad ; Dou, Haiqiang ; Luan, Cheng ; Wang, Yongzhi ; Karagiannopoulos, Alexandros ; Jiang, Xiaoping ; Krus, Ulrika ; Fex, Malin ; Zhang, Quan ; Eliasson, Lena ; Rorsman, Patrik ; Zhang, Enming ; Renström, Erik

Nature communications, 2022-07, Vol.13 (1), p.4237-4237, Article 4237 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
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Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation

King, Ben C. ; Kulak, Klaudia ; Krus, Ulrika ; Rosberg, Rebecca ; Golec, Ewelina ; Wozniak, Katarzyna ; Gomez, Maria F. ; Zhang, Enming ; O'Connell, David J. ; Renström, Erik ; Blom, Anna M.

Cell metabolism, 2019-01, Vol.29 (1), p.202-210.e6 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
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Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Dwivedi, Om Prakash ; Lehtovirta, Mikko ; Hastoy, Benoit ; Chandra, Vikash ; Krentz, Nicole A J ; Kleiner, Sandra ; Jain, Deepak ; Richard, Ann-Marie ; Abaitua, Fernando ; Beer, Nicola L ; Grotz, Antje ; Prasad, Rashmi B ; Hansson, Ola ; Ahlqvist, Emma ; Krus, Ulrika ; Artner, Isabella ; Suoranta, Anu ; Gomez, Daniel ; Baras, Aris ; Champon, Benoite ; Payne, Anthony J ; Moralli, Daniela ; Thomsen, Soren K ; Kramer, Philipp ; Spiliotis, Ioannis ; Ramracheya, Reshma ; Chabosseau, Pauline ; Theodoulou, Andria ; Cheung, Rebecca ; van de Bunt, Martijn ; Flannick, Jason ; Trombetta, Maddalena ; Bonora, Enzo ; Wolheim, Claes B ; Sarelin, Leena ; Bonadonna, Riccardo C ; Rorsman, Patrik ; Davies, Benjamin ; Brosnan, Julia ; McCarthy, Mark I ; Otonkoski, Timo ; Lagerstedt, Jens O ; Rutter, Guy A ; Gromada, Jesper ; Gloyn, Anna L ; Tuomi, Tiinamaija ; Groop, Leif

Nature genetics, 2019-11, Vol.51 (11), p.1596-1606 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets
A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets
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A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets

Taneera, Jalal ; Lang, Stefan ; Sharma, Amitabh ; Fadista, Joao ; Zhou, Yuedan ; Ahlqvist, Emma ; Jonsson, Anna ; Lyssenko, Valeriya ; Vikman, Petter ; Hansson, Ola ; Parikh, Hemang ; Korsgren, Olle ; Soni, Arvind ; Krus, Ulrika ; Zhang, Enming ; Jing, Xing-Jun ; Esguerra, Jonathan L.S. ; Wollheim, Claes B. ; Salehi, Albert ; Rosengren, Anders ; Renström, Erik ; Groop, Leif

Cell metabolism, 2012-07, Vol.16 (1), p.122-134 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets
Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets
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Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets

Bacos, Karl ; Perfilyev, Alexander ; Karagiannopoulos, Alexandros ; Cowan, Elaine ; Ofori, Jones K ; Bertonnier-Brouty, Ludivine ; Rönn, Tina ; Lindqvist, Andreas ; Luan, Cheng ; Ruhrmann, Sabrina ; Ngara, Mtakai ; Nilsson, Åsa ; Gheibi, Sevda ; Lyons, Claire L ; Lagerstedt, Jens O ; Barghouth, Mohammad ; Esguerra, Jonathan Ls ; Volkov, Petr ; Fex, Malin ; Mulder, Hindrik ; Wierup, Nils ; Krus, Ulrika ; Artner, Isabella ; Eliasson, Lena ; Prasad, Rashmi B ; Cataldo, Luis Rodrigo ; Ling, Charlotte

The Journal of clinical investigation, 2023-02, Vol.133 (4), p.1-17 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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7
The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events
The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events
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The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events

Krus, Ulrika ; King, Ben C. ; Nagaraj, Vini ; Gandasi, Nikhil R. ; Sjölander, Jonatan ; Buda, Pawel ; Garcia-Vaz, Eliana ; Gomez, Maria F. ; Ottosson-Laakso, Emilia ; Storm, Petter ; Fex, Malin ; Vikman, Petter ; Zhang, Enming ; Barg, Sebastian ; Blom, Anna M. ; Renström, Erik

Cell metabolism, 2014-05, Vol.19 (5), p.883-890 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets
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Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

Golec, Ewelina ; Ekström, Alexander ; Noga, Maciej ; Omar-Hmeadi, Muhmmad ; Lund, Per-Eric ; Villoutreix, Bruno O ; Krus, Ulrika ; Wozniak, Katarzyna ; Korsgren, Olle ; Renström, Erik ; Barg, Sebastian ; King, Ben C ; Blom, Anna M

Proceedings of the National Academy of Sciences - PNAS, 2022-06, Vol.119 (24), p.e2120083119-e2120083119 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Islet Gene View-a tool to facilitate islet research
Islet Gene View-a tool to facilitate islet research
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Islet Gene View-a tool to facilitate islet research

Asplund, Olof ; Storm, Petter ; Chandra, Vikash ; Hatem, Gad ; Ottosson-Laakso, Emilia ; Mansour-Aly, Dina ; Krus, Ulrika ; Ibrahim, Hazem ; Ahlqvist, Emma ; Tuomi, Tiinamaija ; Renström, Erik ; Korsgren, Olle ; Wierup, Nils ; Ibberson, Mark ; Solimena, Michele ; Marchetti, Piero ; Wollheim, Claes ; Artner, Isabella ; Mulder, Hindrik ; Hansson, Ola ; Otonkoski, Timo ; Groop, Leif ; Prasad, Rashmi B

Life science alliance, 2022-12, Vol.5 (12), p.e202201376 [Periódico revisado por pares]

United States: Life Science Alliance LLC

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10
C4b-binding Protein Protects β-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity
C4b-binding Protein Protects β-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity
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C4b-binding Protein Protects β-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity

Sjölander, Jonatan ; Byman, Elin ; Kulak, Klaudia ; Nilsson, Sara C. ; Zhang, Enming ; Krus, Ulrika ; Westermark, Gunilla T. ; Storm, Petter ; King, Ben C. ; Renström, Erik ; Blom, Anna M.

The Journal of biological chemistry, 2016-10, Vol.291 (41), p.21644-21655 [Periódico revisado por pares]

United States: Elsevier Inc

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