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Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor
Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor
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Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor

Antal, Corina E. ; Hudson, Andrew M. ; Kang, Emily ; Zanca, Ciro ; Wirth, Christopher ; Stephenson, Natalie L. ; Trotter, Eleanor W. ; Gallegos, Lisa L. ; Miller, Crispin J. ; Furnari, Frank B. ; Hunter, Tony ; Brognard, John ; Newton, Alexandra C.

Cell, 2015-01, Vol.160 (3), p.489-502 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin
Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin
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Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin

Kegelman, Timothy P. ; Wu, Bainan ; Das, Swadesh K. ; Talukdar, Sarmistha ; Beckta, Jason M. ; Hu, Bin ; Emdad, Luni ; Valerie, Kristoffer ; Sarkar, Devanand ; Furnari, Frank B. ; Cavenee, Webster K. ; Wei, Jun ; Purves, Angela ; De, Surya K. ; Pellecchia, Maurizio ; Fisher, Paul B.

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (2), p.370-375 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Quantitative Analysis of EGFRvIII Cellular Signaling Networks Reveals a Combinatorial Therapeutic Strategy for Glioblastoma
Quantitative Analysis of EGFRvIII Cellular Signaling Networks Reveals a Combinatorial Therapeutic Strategy for Glioblastoma
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Quantitative Analysis of EGFRvIII Cellular Signaling Networks Reveals a Combinatorial Therapeutic Strategy for Glioblastoma

Huang, Paul H. ; Mukasa, Akitake ; Bonavia, Rudy ; Flynn, Ryan A. ; Brewer, Zachary E. ; Cavenee, Webster K. ; Furnari, Frank B. ; White, Forest M.

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (31), p.12867-12872 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice
Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice
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Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice

Furnari, Melody A ; Jobes, Michelle L ; Nekrasova, Tanya ; Minden, Audrey ; Wagner, George C Skoulakis, Efthimios M. C.

PloS one, 2013-04, Vol.8 (4), p.e61321 [Periódico revisado por pares]

United States: Public Library of Science

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5
Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion
Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion
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Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion

Chaim, Olga Meiri ; Miki, Shunichiro ; Prager, Briana C ; Ma, Jianhui ; Jeong, Anthony Y ; Lara, Jacqueline ; Tran, Nancy K ; Smith, Jeffrey M ; Rich, Jeremy N ; Gutkind, J Silvio ; Miyamoto, Shigeki ; Furnari, Frank B ; Brown, Joan Heller

Scientific reports, 2023-12, Vol.13 (1), p.22412-14, Article 22412 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope
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Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope

Orellana, Laura ; Thorne, Amy H. ; Lema, Rafael ; Gustavsson, Johan ; Parisian, Alison D. ; Hospital, Adam ; Cordeiro, Tiago N. ; Bernadó, Pau ; Scott, Andrew M. ; Brun-Heath, Isabelle ; Lindahl, Erik ; Cavenee, Webster K. ; Furnari, Frank B. ; Orozco, Modesto

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (20), p.10009-10018 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
PCAF Modulates PTEN Activity
PCAF Modulates PTEN Activity
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PCAF Modulates PTEN Activity

Okumura, Koichi ; Mendoza, Michelle ; Bachoo, Robert M. ; DePinho, Ronald A. ; Cavenee, Webster K. ; Furnari, Frank B.

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26562-26568 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240
Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240
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Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240

Fenton, Tim R ; Nathanson, David ; Ponte de Albuquerque, Claudio ; Kuga, Daisuke ; Iwanami, Akio ; Dang, Julie ; Yang, Huijun ; Tanaka, Kazuhiro ; Oba-Shinjo, Sueli Mieko ; Uno, Miyuki ; del Mar Inda, Maria ; Wykosky, Jill ; Bachoo, Robert M ; James, C. David ; DePinho, Ronald A ; Vandenberg, Scott R ; Zhou, Huilin ; Marie, Suely K. N ; Mischel, Paul S ; Cavenee, Webster K ; Furnari, Frank B

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (35), p.14164-14169 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Cellular Transformation by the MSP58 Oncogene Is Inhibited by Its Physical Interaction with the PTEN Tumor Suppressor
Cellular Transformation by the MSP58 Oncogene Is Inhibited by Its Physical Interaction with the PTEN Tumor Suppressor
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Cellular Transformation by the MSP58 Oncogene Is Inhibited by Its Physical Interaction with the PTEN Tumor Suppressor

Okumura, Koichi ; Zhao, Mujun ; DePinho, Ronald A. ; Furnari, Frank B. ; Cavenee, Webster K.

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (8), p.2703-2706 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response
PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response
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PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

Li, Jie ; Kaneda, Megan M ; Ma, Jun ; Li, Ming ; Shepard, Ryan M ; Patel, Kunal ; Koga, Tomoyuki ; Sarver, Aaron ; Furnari, Frank ; Xu, Beibei ; Dhawan, Sanjay ; Ning, Jianfang ; Zhu, Hua ; Wu, Anhua ; You, Gan ; Jiang, Tao ; Venteicher, Andrew S ; Rich, Jeremy N ; Glass, Christopher K ; Varner, Judith A ; Chen, Clark C

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (16), p.1 [Periódico revisado por pares]

United States: National Academy of Sciences

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