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Material Type: Artigo
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BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene ExpressionBarras, David ; Missiaglia, Edoardo ; Wirapati, Pratyaksha ; Sieber, Oliver M ; Jorissen, Robert N ; Love, Chris ; Molloy, Peter L ; Jones, Ian T ; McLaughlin, Stephen ; Gibbs, Peter ; Guinney, Justin ; Simon, Iris M ; Roth, Arnaud D ; Bosman, Fred T ; Tejpar, Sabine ; Delorenzi, MauroClinical cancer research, 2017-01, Vol.23 (1), p.104-115 [Periódico revisado por pares]United States: American Association for Cancer Research IncTexto completo disponível |
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Material Type: Artigo
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Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation StatusVAN CUTSEM, Eric ; KÖHNE, Claus-Henning ; SCHLICHTING, Michael ; ZUBEL, Angela ; CELIK, Ilhan ; ROUGIER, Philippe ; CIARDIELLO, Fortunato ; LANG, István ; FOLPRECHT, Gunnar ; NOWACKI, Marek P ; CASCINU, Stefano ; SHCHEPOTIN, Igor ; MAUREL, Joan ; CUNNINGHAM, David ; TEJPAR, SabineJournal of clinical oncology, 2011-05, Vol.29 (15), p.2011-2019 [Periódico revisado por pares]Alexandria, VA: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancerBudinska, Eva ; Popovici, Vlad ; Tejpar, Sabine ; D'Ario, Giovanni ; Lapique, Nicolas ; Sikora, Katarzyna Otylia ; Di Narzo, Antonio Fabio ; Yan, Pu ; Hodgson, John Graeme ; Weinrich, Scott ; Bosman, Fred ; Roth, Arnaud ; Delorenzi, MauroThe Journal of pathology, 2013-09, Vol.231 (1), p.63-76 [Periódico revisado por pares]Chichester, UK: John Wiley & Sons, LtdTexto completo disponível |
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Material Type: Artigo
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Prognostic Role of KRAS and BRAF in Stage II and III Resected Colon Cancer: Results of the Translational Study on the PETACC-3, EORTC 40993, SAKK 60-00 TrialROTH, Arnaud D ; TEJPAR, Sabine ; ARANDA, Enrique ; NORDLINGER, Bernard ; CISAR, Laura ; LABIANCA, Roberto ; CUNNINGHAM, David ; VAN CUTSEM, Eric ; BOSMAN, Fred ; DELORENZI, Mauro ; PU YAN ; FIOCCA, Roberto ; KLINGBIEL, Dirk ; DIETRICH, Daniel ; BIESMANS, Bart ; BODOKY, György ; BARONE, CarloJournal of clinical oncology, 2010-01, Vol.28 (3), p.466-474 [Periódico revisado por pares]Alexandria, VA: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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Early memory differentiation and cell death resistance in T cells predicts melanoma response to sequential anti-CTLA4 and anti-PD1 immunotherapyVanmeerbeek, Isaure ; Borras, Daniel M ; Sprooten, Jenny ; Bechter, Oliver ; Tejpar, Sabine ; Garg, Abhishek DGenes and immunity, 2021-06, Vol.22 (2), p.108-119 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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PIK3CA Mutations Are Not a Major Determinant of Resistance to the Epidermal Growth Factor Receptor Inhibitor Cetuximab in Metastatic Colorectal CancerPRENEN, Hans ; DE SCHUTTER, Jef ; JACOBS, Bart ; DE ROOCK, Wendy ; BIESMANS, Bart ; CLAES, Bart ; LAMBRECHTS, Diether ; VAN CUTSEM, Eric ; TEJPAR, SabineClinical cancer research, 2009-05, Vol.15 (9), p.3184-3188 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesisLeach, Joshua D G ; Vlahov, Nikola ; Tsantoulis, Petros ; Ridgway, Rachel A ; Flanagan, Dustin J ; Gilroy, Kathryn ; Sphyris, Nathalie ; Vázquez, Ester G ; Vincent, David F ; Faller, William J ; Hodder, Michael C ; Raven, Alexander ; Fey, Sigrid ; Najumudeen, Arafath K ; Strathdee, Douglas ; Nixon, Colin ; Hughes, Mark ; Clark, William ; Shaw, Robin ; van Hooff, Sander R ; Huels, David J ; Medema, Jan Paul ; Barry, Simon T ; Frame, Margaret C ; Unciti-Broceta, Asier ; Leedham, Simon J ; Inman, Gareth J ; Jackstadt, Rene ; Thompson, Barry J ; Campbell, Andrew D ; Tejpar, Sabine ; Sansom, Owen JNature communications, 2021-06, Vol.12 (1), p.3464-15, Article 3464 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Amphiregulin and Epiregulin mRNA Expression in Primary Tumors Predicts Outcome in Metastatic Colorectal Cancer Treated With CetuximabJACOBS, Bart ; DE ROOCK, Wendy ; HUMBLET, Yves ; PENAULT-LLORCA, Frederique ; DE HERTOGH, Gert ; LAURENT-PUIG, Pierre ; VAN CUTSEM, Eric ; TEJPAR, Sabine ; PIESSEVAUX, Hubert ; VAN OIRBEEK, Robin ; BIESMANS, Bart ; SCHUTTER, Jefde ; FIEUWS, Steffen ; VANDESOMPELE, Jo ; PEETERS, Marc ; VAN LAETHEM, Jean-LucJournal of clinical oncology, 2009-10, Vol.27 (30), p.5068-5074 [Periódico revisado por pares]Alexandria, VA: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker studyDomingo, Enric ; Freeman-Mills, Luke ; Rayner, Emily ; Glaire, Mark ; Briggs, Sarah ; Vermeulen, Louis ; Fessler, Evelyn ; Medema, Jan Paul ; Boot, Arnoud ; Morreau, Hans ; van Wezel, Tom ; Liefers, Gerrit-Jan ; Lothe, Ragnhild A ; Danielsen, Stine A ; Sveen, Anita ; Nesbakken, Arild ; Zlobec, Inti ; Lugli, Alessandro ; Koelzer, Viktor H ; Berger, Martin D ; Castellví-Bel, Sergi ; Muñoz, Jenifer ; de Bruyn, Marco ; Nijman, Hans W ; Novelli, Marco ; Lawson, Kay ; Oukrif, Dahmane ; Frangou, Eleni ; Dutton, Peter ; Tejpar, Sabine ; Delorenzi, Mauro ; Kerr, Rachel ; Kerr, David ; Tomlinson, Ian ; Church, David NThe lancet. Gastroenterology & hepatology, 2016-11, Vol.1 (3), p.207-216 [Periódico revisado por pares]NetherlandsSem texto completo |
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Material Type: Artigo
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Clinical Usefulness of EGFR Gene Copy Number as a Predictive Marker in Colorectal Cancer Patients Treated with Cetuximab: A Fluorescent In situ Hybridization StudyPERSONENI, Nicola ; FIEUWS, Steffen ; PEETERS, Marc ; HUMBLET, Yves ; VAN CUTSEM, Eric ; TEJPAR, Sabine ; PIESSEVAUX, Hubert ; DE HERTOGH, Gert ; DE SCHUTTER, Jef ; BIESMANS, Bart ; DE ROOCK, Wendy ; CAPOEN, An ; DEBIEC-RYCHTER, Maria ; LAETHEM, Jean-LucvanClinical cancer research, 2008-09, Vol.14 (18), p.5869-5876 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |