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11 |
Material Type: Artigo
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AM833 Is a Novel Agonist of Calcitonin Family G Protein-Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective AgonistsFletcher, Madeleine M ; Keov, Peter ; Truong, Tin T ; Mennen, Grace ; Hick, Caroline A ; Zhao, Peishen ; Furness, Sebastian G B ; Kruse, Thomas ; Clausen, Trine R ; Wootten, Denise ; Sexton, Patrick MThe Journal of pharmacology and experimental therapeutics, 2021-06, Vol.377 (3), p.417-440 [Periódico revisado por pares]United StatesTexto completo disponível |
12 |
Material Type: Artigo
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Seletalisib: Characterization of a Novel, Potent, and Selective Inhibitor of PI3K δAllen, Rodger A ; Brookings, Daniel C ; Powell, Mark J ; Delgado, Jean ; Shuttleworth, Lindsay K ; Merriman, Mark ; Fahy, Ian J ; Tewari, Roohi ; Silva, John P ; Healy, Louise J ; Davies, Gareth C G ; Twomey, Breda ; Cutler, Rona M ; Kotian, Apoorva ; Crosby, Andrea ; McCluskey, Gillian ; Watt, Gillian F ; Payne, AndrewThe Journal of pharmacology and experimental therapeutics, 2017-06, Vol.361 (3), p.429-440 [Periódico revisado por pares]United StatesTexto completo disponível |
13 |
Material Type: Artigo
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Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and miceSuzuki, Masayuki ; Honda, Kiyofumi ; Fukazawa, Masanori ; Ozawa, Kazuharu ; Hagita, Hitoshi ; Kawai, Takahiro ; Takeda, Minako ; Yata, Tatsuo ; Kawai, Mio ; Fukuzawa, Taku ; Kobayashi, Takamitsu ; Sato, Tsutomu ; Kawabe, Yoshiki ; Ikeda, SachiyaThe Journal of pharmacology and experimental therapeutics, 2012-06, Vol.341 (3), p.692-701 [Periódico revisado por pares]United StatesTexto completo disponível |
14 |
Material Type: Artigo
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Chronic Ca 2+ /Calmodulin-Dependent Protein Kinase II Inhibition Rescues Advanced Heart FailureLiu, Yixi ; Shao, Qun ; Cheng, Heng-Jie ; Li, Tiankai ; Zhang, Xiaowei ; Callahan, Michael F ; Herrington, David ; Kitzman, Dalane ; Zhao, David ; Cheng, Che-PingThe Journal of pharmacology and experimental therapeutics, 2021-06, Vol.377 (3), p.316-325 [Periódico revisado por pares]United StatesTexto completo disponível |
15 |
Material Type: Artigo
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(R)-8-(3-Amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a Novel Xanthine-Based Dipeptidyl Peptidase 4 Inhibitor, Has a Superior Potency and Longer Duration of Action Compared with Other Dipeptidyl Peptidase-4 InhibitorsThomas, Leo ; Eckhardt, Matthias ; Langkopf, Elke ; Tadayyon, Moh ; Himmelsbach, Frank ; Mark, MichaelThe Journal of pharmacology and experimental therapeutics, 2008-04, Vol.325 (1), p.175-182 [Periódico revisado por pares]United States: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
16 |
Material Type: Artigo
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Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulatorMaeda, Kenji ; Sugino, Haruhiko ; Akazawa, Hitomi ; Amada, Naoki ; Shimada, Jun ; Futamura, Takashi ; Yamashita, Hiroshi ; Ito, Nobuaki ; McQuade, Robert D ; Mørk, Arne ; Pehrson, Alan L ; Hentzer, Morten ; Nielsen, Vibeke ; Bundgaard, Christoffer ; Arnt, Jørn ; Stensbøl, Tine Bryan ; Kikuchi, TetsuroThe Journal of pharmacology and experimental therapeutics, 2014-09, Vol.350 (3), p.589-604 [Periódico revisado por pares]United StatesTexto completo disponível |
17 |
Material Type: Artigo
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CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administrationMoretto, Nadia ; Caruso, Paola ; Bosco, Raffaella ; Marchini, Gessica ; Pastore, Fiorella ; Armani, Elisabetta ; Amari, Gabriele ; Rizzi, Andrea ; Ghidini, Eleonora ; De Fanti, Renato ; Capaldi, Carmelida ; Carzaniga, Laura ; Hirsch, Emilio ; Buccellati, Carola ; Sala, Angelo ; Carnini, Chiara ; Patacchini, Riccardo ; Delcanale, Maurizio ; Civelli, Maurizio ; Villetti, Gino ; Facchinetti, FabrizioThe Journal of pharmacology and experimental therapeutics, 2015-03, Vol.352 (3), p.559-567 [Periódico revisado por pares]United StatesTexto completo disponível |
18 |
Material Type: Artigo
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RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodentsXu, Daigen ; Kim, Yong ; Postelnek, Jennifer ; Vu, Minh Diem ; Hu, Dong-Qing ; Liao, Cheng ; Bradshaw, Mike ; Hsu, Jonathan ; Zhang, Jun ; Pashine, Achal ; Srinivasan, Dinesh ; Woods, John ; Levin, Anita ; O'Mahony, Alison ; Owens, Timothy D ; Lou, Yan ; Hill, Ronald J ; Narula, Satwant ; DeMartino, Julie ; Fine, Jay SThe Journal of pharmacology and experimental therapeutics, 2012-04, Vol.341 (1), p.90-103 [Periódico revisado por pares]United StatesTexto completo disponível |
19 |
Material Type: Artigo
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(-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol hydrochloride (tapentadol HCl): a novel mu-opioid receptor agonist/norepinephrine reuptake inhibitor with broad-spectrum analgesic propertiesTzschentke, Thomas M ; Christoph, Thomas ; Kögel, Babette ; Schiene, Klaus ; Hennies, Hagen-Heinrich ; Englberger, Werner ; Haurand, Michael ; Jahnel, Ulrich ; Cremers, Thomas I F H ; Friderichs, Elmar ; De Vry, JeanThe Journal of pharmacology and experimental therapeutics, 2007-10, Vol.323 (1), p.265-276 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Specific Lowering of Asymmetric Dimethylarginine by Pharmacological Dimethylarginine Dimethylaminohydrolase Improves Endothelial Function, Reduces Blood Pressure and Ischemia-Reperfusion InjuryLee, Young ; Mehrotra, Purvi ; Basile, David ; Ullah, Mahbub ; Singh, Arshnoor ; Skill, Nicholas ; Younes, Subhi Talal ; Sasser, Jennifer ; Shekhar, Anantha ; Singh, JaipalThe Journal of pharmacology and experimental therapeutics, 2021-02, Vol.376 (2), p.181-189 [Periódico revisado por pares]United States: The American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |