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Pharmacophore-guided lead optimization: The rational design of a non-zinc coordinating, sub-micromolar inhibitor of the botulinum neurotoxin serotype a metalloprotease
Pharmacophore-guided lead optimization: The rational design of a non-zinc coordinating, sub-micromolar inhibitor of the botulinum neurotoxin serotype a metalloprotease
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Pharmacophore-guided lead optimization: The rational design of a non-zinc coordinating, sub-micromolar inhibitor of the botulinum neurotoxin serotype a metalloprotease

Burnett, J.C. ; Wang, C. ; Nuss, J.E. ; Nguyen, T.L. ; Hermone, A.R. ; Schmidt, J.J. ; Gussio, R. ; Wipf, P. ; Bavari, S.

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5811-5813 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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2
Membrane protein structure determination by solid state NMR
Membrane protein structure determination by solid state NMR
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Membrane protein structure determination by solid state NMR

Watts, A ; Burnett, I J ; Glaubitz, C ; Gröbner, G ; Middleton, D A ; Spooner, P J ; Watts, J A ; Williamson, P T

Natural product reports, 1999-08, Vol.16 (4), p.419-423 [Periódico revisado por pares]

England

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3
Conformational sampling of the botulinum neurotoxin serotype a light chain: implications for inhibitor binding
Conformational sampling of the botulinum neurotoxin serotype a light chain: implications for inhibitor binding
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Conformational sampling of the botulinum neurotoxin serotype a light chain: implications for inhibitor binding

Burnett, James C. ; Schmidt, James J. ; McGrath, Connor F. ; Nguyen, Tam L. ; Hermone, Ann R. ; Panchal, Rekha G. ; Vennerstrom, Jonathan L. ; Kodukula, Krishna ; Zaharevitz, Daniel W. ; Gussio, Rick ; Bavari, Sina

Bioorganic & medicinal chemistry, 2005-01, Vol.13 (2), p.333-341 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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4
Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors
Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors
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Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors

Tasker, Nikhil R. ; Rastelli, Ettore J. ; Burnett, James C. ; Sharlow, Elizabeth R. ; Lazo, John S. ; Wipf, Peter

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2008-2015 [Periódico revisado por pares]

England: Elsevier Ltd

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5
Discovery and characterization of novel TRPML1 agonists
Discovery and characterization of novel TRPML1 agonists
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Discovery and characterization of novel TRPML1 agonists

Peng, Xiaowen ; Holler, Christopher J ; Alves, Anna-Maria F ; Oliviera, Michelle G ; Speake, Michael ; Pugliese, Angelo ; Oskouei, Mina R ; de Freitas, Ivan D ; Chen, Angela Y-P ; Gallegos, Richard ; McTighe, Stephanie M ; Koenig, Gerhard ; Hurst, Raymond S ; Blain, Jean-François ; Lanter, James C ; Burnett, Duane A

Bioorganic & medicinal chemistry letters, 2024-01, Vol.98, p.129595-129595, Article 129595 [Periódico revisado por pares]

England

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6
Design and synthesis of water soluble β-aminosulfone analogues of SCH 900229 as γ-secretase inhibitors
Design and synthesis of water soluble β-aminosulfone analogues of SCH 900229 as γ-secretase inhibitors
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Design and synthesis of water soluble β-aminosulfone analogues of SCH 900229 as γ-secretase inhibitors

Wu, Wen-Lian ; Burnett, Duane A. ; Clader, John ; Greenlee, William J. ; Jiang, Qin ; Hyde, Lynn A. ; Del Vecchio, Robert A. ; Cohen-Williams, Mary E. ; Song, Lixin ; Lee, Julie ; Terracina, Giuseppe ; Zhang, Qi ; Nomeir, Amin ; Parker, Eric M. ; Zhang, Lili

Bioorganic & medicinal chemistry letters, 2016-12, Vol.26 (23), p.5836-5841 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Activity Based Protein Profiling Leads to Identification of Novel Protein Targets for Nerve Agent VX
Activity Based Protein Profiling Leads to Identification of Novel Protein Targets for Nerve Agent VX
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Activity Based Protein Profiling Leads to Identification of Novel Protein Targets for Nerve Agent VX

Carmany, Dan ; Walz, Andrew J ; Hsu, Fu-Lian ; Benton, Bernard ; Burnett, David ; Gibbons, Jennifer ; Noort, Daan ; Glaros, Trevor ; Sekowski, Jennifer W

Chemical research in toxicology, 2017-04, Vol.30 (4), p.1076-1084 [Periódico revisado por pares]

United States: American Chemical Society

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8
Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain
Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain
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Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain

Bennett, Chad E. ; Burnett, Duane A. ; Greenlee, William J. ; Knutson, Chad E. ; Korakas, Peter ; Li, Cheng ; Tulshian, Deen ; Wu, Wen-Lian ; Bertorelli, Rosalia ; Fredduzzi, Silva ; Grilli, Mariagrazia ; Lozza, Gianluca ; Reggiani, Angelo ; Veltri, Alessio

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1575-1578 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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9
Structure activity relationship studies of tricyclic bispyran sulfone γ-secretase inhibitors
Structure activity relationship studies of tricyclic bispyran sulfone γ-secretase inhibitors
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Structure activity relationship studies of tricyclic bispyran sulfone γ-secretase inhibitors

Wu, Wen-Lian ; Asberom, Theodros ; Bara, Thomas ; Bennett, Chad ; Burnett, Duane A. ; Clader, John ; Domalski, Martin ; Greenlee, William J. ; Josien, Hubert ; McBriar, Mark ; Rajagopalan, Murali ; Vicarel, Monica ; Xu, Ruo ; Hyde, Lynn A. ; Del Vecchio, Robert A. ; Cohen-Williams, Mary E. ; Song, Lixin ; Lee, Julie ; Terracina, Giuseppe ; Zhang, Qi ; Nomeir, Amin ; Parker, Eric M. ; Zhang, Lili

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.844-849 [Periódico revisado por pares]

England: Elsevier Ltd

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10
Tricyclic sulfones as orally active γ-secretase inhibitors: Synthesis and structure–activity relationship studies
Tricyclic sulfones as orally active γ-secretase inhibitors: Synthesis and structure–activity relationship studies
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Tricyclic sulfones as orally active γ-secretase inhibitors: Synthesis and structure–activity relationship studies

Sasikumar, T.K. ; Qiang, Li ; Burnett, Duane A. ; Cole, David ; Xu, Ruo ; Li, Hongmei ; Greenlee, William J. ; Clader, John ; Zhang, Lili ; Hyde, Lynn

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (12), p.3632-3635 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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