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Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes
Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes
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Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes

Yaghootkar, Hanieh ; Scott, Robert A ; White, Charles C ; Zhang, Weihua ; Speliotes, Elizabeth ; Munroe, Patricia B ; Ehret, Georg B ; Bis, Joshua C ; Fox, Caroline S ; Walker, Mark ; Borecki, Ingrid B ; Knowles, Joshua W ; Yerges-Armstrong, Laura ; Ohlsson, Claes ; Perry, John R B ; Chambers, John C ; Kooner, Jaspal S ; Franceschini, Nora ; Langenberg, Claudia ; Hivert, Marie-France ; Dastani, Zari ; Richards, J Brent ; Semple, Robert K ; Frayling, Timothy M

Diabetes (New York, N.Y.), 2014-12, Vol.63 (12), p.4369-4377 [Periódico revisado por pares]

United States: American Diabetes Association

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2
Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
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Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes

ROSENGREN, Anders H ; BRAUN, Matthias ; EDLUND, Anna ; GRAM PEDERSEN, Morten ; JONSSON, Anna ; RAMRACHEYA, Reshma ; YUNZHAO TANG ; WALKER, Jonathan N ; BARRETT, Amy ; JOHNSON, Paul R. V ; LYSSENKO, Valeriya ; MCCARTHY, Mark I ; MAHDI, Taman ; GROOP, Leif ; SALEHI, Albert ; GLOYN, Anna L ; RENSTRÖM, Erik ; RORSMAN, Patrik ; ELIASSON, Lena ; ANDERSSON, Sofia A ; TRAVERS, Mary E ; SHIGETO, Makoto ; ZHANG, Enming ; ALMGREN, Peter ; LADENVALL, Claes ; AXELSSON, Annika S

Diabetes (New York, N.Y.), 2012-07, Vol.61 (7), p.1726-1733 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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3
Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity
Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity
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Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

DIMAS, Antigone S ; LAGOU, Vasiliki ; CI SONG ; FISCHER-ROSINSKY, Antje ; BOESGAARD, Trine Welløv ; GRARUP, Niels ; ABBASI, Fahim A ; ASSIMES, Themistocles L ; KE HAO ; XIA YANG ; LECOEUR, Cécile ; BARROSO, Inês ; BARKER, Adam ; BONNYCASTLE, Lori L ; BÖTTCHER, Yvonne ; BUMPSTEAD, Suzannah ; CHINES, Peter S ; ERDOS, Michael R ; GRAESSLER, Jurgen ; KOVACS, Peter ; MORKEN, Mario A ; NARISU, Narisu ; PAYNE, Felicity ; KNOWLES, Joshua W ; STANCAKOVA, Alena ; SWIFT, Amy J ; TÖNJES, Anke ; BORNSTEIN, Stefan R ; CAUCHI, Stéphane ; FROGUEL, Philippe ; MEYRE, David ; SCHWARZ, Peter E. H ; HÄRING, Hans-Ulrich ; SMITH, Ulf ; MÄGI, Reedik ; BOEHNKE, Michael ; BERGMAN, Richard N ; COLLINS, Francis S ; MOHLKE, Karen L ; TUOMILEHTO, Jaakko ; QUERTEMOUS, Thomas ; LIND, Lars ; HANSEN, Torben ; PEDERSEN, Oluf ; WALKER, Mark ; HIVERT, Marie-France ; PFEIFFER, Andreas F. H ; SPRANGER, Joachim ; STUMVOLL, Michael ; MEIGS, James B ; WAREHAM, Nicholas J ; KUUSISTO, Johanna ; LAAKSO, Markku ; LANGENBERG, Claudia ; DUPUIS, Josée ; BENAZZO, Andrea ; RYBIN, Denis ; JACKSON, Anne U ; STRINGHAM, Heather M

Diabetes (New York, N.Y.), 2014-06, Vol.63 (6), p.2158-2171 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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4
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes
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A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

van Zuydam, Natalie R ; Ahlqvist, Emma ; Sandholm, Niina ; Deshmukh, Harshal ; Rayner, N William ; Abdalla, Moustafa ; Ladenvall, Claes ; Ziemek, Daniel ; Fauman, Eric ; Robertson, Neil R ; McKeigue, Paul M ; Valo, Erkka ; Forsblom, Carol ; Harjutsalo, Valma ; Perna, Annalisa ; Rurali, Erica ; Marcovecchio, M Loredana ; Igo, Jr, Robert P ; Salem, Rany M ; Perico, Norberto ; Lajer, Maria ; Käräjämäki, Annemari ; Imamura, Minako ; Kubo, Michiaki ; Takahashi, Atsushi ; Sim, Xueling ; Liu, Jianjun ; van Dam, Rob M ; Jiang, Guozhi ; Tam, Claudia H T ; Luk, Andrea O Y ; Lee, Heung Man ; Lim, Cadmon K P ; Szeto, Cheuk Chun ; So, Wing Yee ; Chan, Juliana C N ; Ang, Su Fen ; Dorajoo, Rajkumar ; Wang, Ling ; Clara, Tan Si Hua ; McKnight, Amy-Jayne ; Duffy, Seamus ; Pezzolesi, Marcus G ; Marre, Michel ; Gyorgy, Beata ; Hadjadj, Samy ; Hiraki, Linda T ; Ahluwalia, Tarunveer S ; Almgren, Peter ; Schulz, Christina-Alexandra ; Orho-Melander, Marju ; Linneberg, Allan ; Christensen, Cramer ; Witte, Daniel R ; Grarup, Niels ; Brandslund, Ivan ; Melander, Olle ; Paterson, Andrew D ; Tregouet, David ; Maxwell, Alexander P ; Lim, Su Chi ; Ma, Ronald C W ; Tai, E Shyong ; Maeda, Shiro ; Lyssenko, Valeriya ; Tuomi, Tiinamaija ; Krolewski, Andrzej S ; Rich, Stephen S ; Hirschhorn, Joel N ; Florez, Jose C ; Dunger, David ; Pedersen, Oluf ; Hansen, Torben ; Rossing, Peter ; Remuzzi, Giuseppe ; Brosnan, Mary Julia ; Palmer, Colin N A ; Groop, Per-Henrik ; Colhoun, Helen M ; Groop, Leif C ; McCarthy, Mark I

Diabetes (New York, N.Y.), 2018-07, Vol.67 (7), p.1414-1427 [Periódico revisado por pares]

United States: American Diabetes Association

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5
Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes
Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes
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Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes

GLOYN, Anna L ; WEEDON, Michael N ; MCCARTHY, Mark I ; HATTERSLEY, Andrew T ; FRAYLING, Timothy M ; OWEN, Katharine R ; TURNER, Martina J ; KNIGHT, Bridget A ; HITMAN, Graham ; WALKER, Mark ; LEVY, Jonathan C ; SAMPSON, Mike ; HALFORD, Stephanie

Diabetes (New York, N.Y.), 2003-02, Vol.52 (2), p.568-572 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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6
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
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Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

STRAWBRIDGE, Rona J ; DUPUIS, Josée ; NICA, Alexandra ; WHEELER, Eleanor ; HAN CHEN ; VOIGHT, Benjamin F ; TANEERA, Jalal ; KANONI, Stavroula ; PEDEN, John F ; TURRINI, Fabiola ; GUSTAFSSON, Stefan ; ZABENA, Carina ; PROKOPENKO, Inga ; ALMGREN, Peter ; BARKER, David J. P ; BARNES, Daniel ; DENNISON, Elaine M ; ERIKSSON, Johan G ; ERIKSSON, Per ; EURY, Elodie ; FOLKERSEN, Lasse ; FOX, Caroline S ; FRAYLING, Timothy M ; BARKER, Adam ; GOEL, Anuj ; GU, Harvest F ; HORIKOSHI, Momoko ; ISOMAA, Bo ; JACKSON, Anne U ; JAMESON, Karen A ; KAJANTIE, Eero ; KERR-CONTE, Julie ; KUULASMAA, Teemu ; KUUSISTO, Johanna ; AHLQVIST, Emma ; LOOS, Ruth J. F ; JIAN'AN LUAN ; MAKRILAKIS, Konstantinos ; MANNING, Alisa K ; MARTINEZ-LARRAD, Maria Teresa ; NARISU, Narisu ; MANNILA, Maria Nastase ; OHRVIK, John ; OSMOND, Clive ; PASCOE, Laura ; RYBIN, Denis ; PAYNE, Felicity ; SAYER, Avan A ; SENNBLAD, Bengt ; SILVEIRA, Angela ; STANCAKOVA, Alena ; STIRRUPS, Kathy ; SWIFT, Amy J ; SYVÄNEN, Ann-Christine ; PETRIE, John R ; TRAVERS, Mary E ; BOUATIA-NAJI, Nabila ; DIMAS, Antigone S

Diabetes (New York, N.Y.), 2011-10, Vol.60 (10), p.2624-2634 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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7
Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes
Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes
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Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

WINCKLER, Wendy ; WEEDON, Michael N ; HITMAN, Graham ; HATTERSLEY, Andrew T ; MCCARTHY, Mark I ; ARDLIE, Kristin G ; HIRSCHHORN, Joel N ; DALY, Mark J ; FRAYLING, Timothy M ; GROOP, Leif ; ALTSHULER, David ; GRAHAM, Robert R ; MCCARROLL, Steven A ; PURCELL, Shaun ; ALMGREN, Peter ; TUOMI, Tiinamaija ; GAUDET, Daniel ; BENGTSSON BOSTRÖM, Kristina ; WALKER, Mark

Diabetes (New York, N.Y.), 2007-03, Vol.56 (3), p.685-693 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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8
A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants
A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants
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A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

Wood, Andrew R ; Jonsson, Anna ; Jackson, Anne U ; Wang, Nan ; van Leewen, Nienke ; Palmer, Nicholette D ; Kobes, Sayuko ; Deelen, Joris ; Boquete-Vilarino, Lorena ; Paananen, Jussi ; Stančáková, Alena ; Boomsma, Dorret I ; de Geus, Eco J C ; Eekhoff, Elisabeth M W ; Fritsche, Andreas ; Kramer, Mark ; Nijpels, Giel ; Simonis-Bik, Annemarie ; van Haeften, Timon W ; Mahajan, Anubha ; Boehnke, Michael ; Bergman, Richard N ; Tuomilehto, Jaakko ; Collins, Francis S ; Mohlke, Karen L ; Banasik, Karina ; Groves, Christopher J ; McCarthy, Mark I ; Pearson, Ewan R ; Natali, Andrea ; Mari, Andrea ; Buchanan, Thomas A ; Taylor, Kent D ; Xiang, Anny H ; Gjesing, Anette P ; Grarup, Niels ; Eiberg, Hans ; Pedersen, Oluf ; Chen, Yii-Derr ; Laakso, Markku ; Norris, Jill M ; Smith, Ulf ; Wagenknecht, Lynne E ; Baier, Leslie ; Bowden, Donald W ; Hansen, Torben ; Walker, Mark ; Watanabe, Richard M ; 't Hart, Leen M ; Hanson, Robert L ; Frayling, Timothy M

Diabetes (New York, N.Y.), 2017-08, Vol.66 (8), p.2296-2309 [Periódico revisado por pares]

United States: American Diabetes Association

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9
Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion
Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion
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Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

Yaghootkar, Hanieh ; Stancáková, Alena ; Freathy, Rachel M ; Vangipurapu, Jagadish ; Weedon, Michael N ; Xie, Weijia ; Wood, Andrew R ; Ferrannini, Ele ; Mari, Andrea ; Ring, Susan M ; Lawlor, Debbie A ; Davey Smith, George ; Jørgensen, Torben ; Hansen, Torben ; Pedersen, Oluf ; Steinthorsdottir, Valgerdur ; Guðbjartsson, Daniel F ; Thorleifsson, Gudmar ; Thorsteinsdottir, Unnur ; Stefansson, Kari ; Hattersley, Andrew T ; Walker, Mark ; Morris, Andrew D ; McCarthy, Mark I ; Palmer, Colin N A ; Laakso, Markku ; Frayling, Timothy M

Diabetes (New York, N.Y.), 2015-06, Vol.64 (6), p.2279-2285 [Periódico revisado por pares]

United States: American Diabetes Association

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10
Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
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Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes

WEIJIA XIE ; WOOD, Andrew R ; HÄRING, Hans ; HANSEN, Torben ; PEDERSEN, Oluf ; SMITH, Ulf ; LAAKSO, Markku ; DEKKER, Jacqueline M ; NOLAN, John J ; GROOP, Leif ; FERRANNINI, Ele ; ADAM, Klaus-Peter ; LYSSENKO, Valeriya ; GALL, Walter E ; FRAYLING, Timothy M ; WALKER, Mark ; WEEDON, Michael N ; KNOWLES, Joshua W ; ALKAYYALI, Sami ; ASSIMES, Themistocles L ; QUERTERMOUS, Thomas ; ABBASI, Fahim ; PAANANEN, Jussi

Diabetes (New York, N.Y.), 2013-06, Vol.62 (6), p.2141-2150 [Periódico revisado por pares]

Alexandria, VA: American Diabetes Association

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