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11
Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein
Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein
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Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein

Mitchell, Aaron C. ; Kannan, Deepti ; Hunter, Sean A. ; Parra Sperberg, R. Andres ; Chang, Cheryl H. ; Cochran, Jennifer R.

The Journal of biological chemistry, 2018-04, Vol.293 (14), p.4969-4980 [Periódico revisado por pares]

United States: Elsevier Inc

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12
Targeting Fibroblast Activation Protein: Radiosynthesis and Preclinical Evaluation of an 18 F-Labeled FAP Inhibitor
Targeting Fibroblast Activation Protein: Radiosynthesis and Preclinical Evaluation of an 18 F-Labeled FAP Inhibitor
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Targeting Fibroblast Activation Protein: Radiosynthesis and Preclinical Evaluation of an 18 F-Labeled FAP Inhibitor

Toms, Johannes ; Kogler, Jürgen ; Maschauer, Simone ; Daniel, Christoph ; Schmidkonz, Christian ; Kuwert, Torsten ; Prante, Olaf

Journal of Nuclear Medicine, 2020-12, Vol.61 (12), p.1806-1813 [Periódico revisado por pares]

United States

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13
Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk)
Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk)
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Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk)

Bonaca, Marc P ; Nault, Patrice ; Giugliano, Robert P ; Keech, Anthony C ; Pineda, Armando Lira ; Kanevsky, Estella ; Kuder, Julia ; Murphy, Sabina A ; Jukema, J Wouter ; Lewis, Basil S ; Tokgozoglu, Lale ; Somaratne, Ransi ; Sever, Peter S ; Pedersen, Terje R ; Sabatine, Marc S

Circulation (New York, N.Y.), 2018-01, Vol.137 (4), p.338-350 [Periódico revisado por pares]

United States: by the American College of Cardiology Foundation and the American Heart Association, Inc

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14
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
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Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

Hander Tim ; Fernández-Fernández, Álvaro D ; Kumpf, Robert P ; Willems, Patrick ; Schatowitz Hendrik ; Rombaut Debbie ; Staes An ; Nolf Jonah ; Pottie, Robin ; Yao Panfeng ; Gonçalves, Amanda ; Pavie Benjamin ; Boller, Thomas ; Gevaert Kris ; Frank, Van Breusegem ; Bartels, Sebastian ; Stael Simon

Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6433) [Periódico revisado por pares]

Washington: The American Association for the Advancement of Science

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15
Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors
Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors
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Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors

Szakács, Dávid ; Kocsis, Andrea ; Szász, Róbert ; Gál, Péter ; Pál, Gábor

The Journal of biological chemistry, 2019-05, Vol.294 (20), p.8227-8237 [Periódico revisado por pares]

United States: Elsevier Inc

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16
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
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The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins

Malaker, Stacy A. ; Pedram, Kayvon ; Ferracane, Michael J. ; Bensing, Barbara A. ; Krishnan, Venkatesh ; Pett, Christian ; Yu, Jin ; Woods, Elliot C. ; Kramer, Jessica R. ; Westerlind, Ulrika ; Dorigo, Oliver ; Bertozzi, Carolyn R.

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (15), p.7278-7287 [Periódico revisado por pares]

United States: National Academy of Sciences

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17
Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease
Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease
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Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease

PERNI, Robert B ; ALMQUIST, Susan J ; HEISER, Angela ; KALKERI, Gururaj ; KOLACZKOWSKI, Elaine ; KAI LIN ; LUONG, Yu-Ping ; GOVINDA RAO, B ; TAYLOR, William P ; THOMSON, John A ; TUNG, Roger D ; YUNYI WEI ; BYRN, Randal A ; KWONG, Ann D ; CHAO LIN ; CHANDORKAR, Gurudatt ; CHATURVEDI, Pravin R ; COURTNEY, Lawrence F ; DECKER, Caroline J ; DINEHART, Kirk ; GATES, Cynthia A ; HARBESON, Scott L

Antimicrobial Agents and Chemotherapy, 2006-03, Vol.50 (3), p.899-909 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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18
252 Examining the modulatory effects of anti-serine protease antibodies upon factor Xa, thrombin and complement interactions
252 Examining the modulatory effects of anti-serine protease antibodies upon factor Xa, thrombin and complement interactions
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252 Examining the modulatory effects of anti-serine protease antibodies upon factor Xa, thrombin and complement interactions

McDonnell, Thomas C R ; Wincup, Christopher ; Ripoll, Vera ; Gerveshi, Carina ; Rahman, Anisur ; Mackie, Ian ; Botto, Marina ; Giles, Ian

Rheumatology (Oxford, England), 2018-04, Vol.57 (suppl_3) [Periódico revisado por pares]

Oxford: Oxford University Press

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19
An integrative view of serpins in health and disease: the contribution of SerpinA3
An integrative view of serpins in health and disease: the contribution of SerpinA3
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An integrative view of serpins in health and disease: the contribution of SerpinA3

Sánchez-Navarro, Andrea ; González-Soria, Isaac ; Caldiño-Bohn, Rebecca ; Bobadilla, Norma A

American Journal of Physiology: Cell Physiology, 2021-01, Vol.320 (1), p.C106-C118, Article ajpcell.00366.2020 [Periódico revisado por pares]

United States: American Physiological Society

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20
Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein
Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein
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Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein

Schmidt, Karin ; Gardill, Bernd R. ; Kern, Alina ; Kirchweger, Peter ; Börsch, Michael ; Muller, Yves A.

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (22), p.5744-5749 [Periódico revisado por pares]

United States: National Academy of Sciences

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