Result Number | Material Type | Add to My Shelf Action | Record Details and Options |
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1 |
Material Type: Artigo
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Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2)Witter, David J. ; Harrington, Paul ; Wilson, Kevin J. ; Chenard, Melissa ; Fleming, Judith C. ; Haines, Brian ; Kral, Astrid M. ; Secrist, J. Paul ; Miller, Thomas A.Bioorganic & medicinal chemistry, 2008-01, Vol.18 (2), p.726-731 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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2 |
Material Type: Artigo
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Lovastatin Nonaketide Synthase Catalyzes an Intramolecular Diels−Alder Reaction of a Substrate AnalogueAuclair, Karine ; Sutherland, Andrew ; Kennedy, Jonathan ; Witter, David J ; Van den Heever, Johan P ; Hutchinson, C. Richard ; Vederas, John CJournal of the American Chemical Society, 2000-11, Vol.122 (46), p.11519-11520 [Periódico revisado por pares]American Chemical SocietyTexto completo disponível |
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3 |
Material Type: Artigo
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A Divergent Approach to the Synthesis of 3-Substituted-2-pyrazolines: Suzuki Cross-Coupling of 3-Sulfonyloxy-2-pyrazolinesGrimm, Jonathan B ; Wilson, Kevin J ; Witter, David JJournal of organic chemistry, 2009-08, Vol.74 (16), p.6390-6393 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
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4 |
Material Type: Artigo
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A New Strategy for the Synthesis of Benzylic Sulfonamides: Palladium-Catalyzed Arylation and Sulfonamide MetathesisGrimm, Jonathan B ; Katcher, Matthew H ; Witter, David J ; Northrup, Alan BJournal of organic chemistry, 2007-10, Vol.72 (21), p.8135-8138 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
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5 |
Material Type: Artigo
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Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2)HEIDEBRECHT, Richard W ; CHENARD, Melissa ; KRAL, Astrid M ; MIDDLETON, Richard E ; MUSHTI, Chandrasekhar ; OZEROVA, Nicole ; SZEWCZAK, Alexander A ; HONGMEI WANG ; WILSON, Kevin ; WITTER, David J ; SECRIST, J. Paul ; MILLER, Thomas A ; CLOSE, Joshua ; DAHLBERG, William K ; FLEMING, Judith ; GRIMM, Jonathan B ; HAMILL, Julie E ; HARSCH, Andreas ; HAINES, Brian B ; HUGHES, BethanyBioorganic & medicinal chemistry letters, 2009-04, Vol.19 (7), p.2053-2058 [Periódico revisado por pares]Amsterdam: ElsevierTexto completo disponível |
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6 |
Material Type: Artigo
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Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)Methot, Joey L. ; Chakravarty, Prasun K. ; Chenard, Melissa ; Close, Joshua ; Cruz, Jonathan C. ; Dahlberg, William K. ; Fleming, Judith ; Hamblett, Christopher L. ; Hamill, Julie E. ; Harrington, Paul ; Harsch, Andreas ; Heidebrecht, Richard ; Hughes, Bethany ; Jung, Joon ; Kenific, Candia M. ; Kral, Astrid M. ; Meinke, Peter T. ; Middleton, Richard E. ; Ozerova, Nicole ; Sloman, David L. ; Stanton, Matthew G. ; Szewczak, Alexander A. ; Tyagarajan, Sriram ; Witter, David J. ; Paul Secrist, J. ; Miller, Thomas A.Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.973-978 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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7 |
Material Type: Artigo
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Putative Diels−Alder-Catalyzed Cyclization during the Biosynthesis of LovastatinWitter, David J ; Vederas, John CJournal of organic chemistry, 1996-04, Vol.61 (8), p.2613-2623 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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8 |
Material Type: Artigo
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Design and synthesis of SH3 domain binding ligands: Modifications of the consensus sequence XPpXPWitter, David J. ; Famiglietti, Sara J. ; Cambier, John C. ; Castelhano, Arlindo L.Bioorganic & medicinal chemistry letters, 1998-11, Vol.8 (22), p.3137-3142 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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9 |
Material Type: Artigo
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Aminosuberoyl hydroxamic acids (ASHAs): A potent new class of HDAC inhibitorsBelvedere, Sandro ; Witter, David J. ; Yan, Jiaming ; Secrist, J. Paul ; Richon, Victoria ; Miller, Thomas A.Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (14), p.3969-3971 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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10 |
Material Type: Artigo
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Revision of the biosynthetic origin of oxygens in mevinolin (lovastatin), a hypocholesterolemic drug from Aspergillus terreus MF 4845Yoshizawa, Yuko ; Witter, David J ; Liu, Yaoquan ; Vederas, John CJournal of the American Chemical Society, , Vol.116 (6), p.2693-2694 [Periódico revisado por pares]American Chemical SocietyTexto completo disponível |