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Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling
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Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling

Hrdinka, Matous ; Schlicher, Lisa ; Dai, Bing ; Pinkas, Daniel M ; Bufton, Joshua C ; Picaud, Sarah ; Ward, Jennifer A ; Rogers, Catherine ; Suebsuwong, Chalada ; Nikhar, Sameer ; Cuny, Gregory D ; Huber, Kilian VM ; Filippakopoulos, Panagis ; Bullock, Alex N ; Degterev, Alexei ; Gyrd‐Hansen, Mads

The EMBO journal, 2018-09, Vol.37 (17), p.n/a [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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12
Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models
Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models
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Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models

Zhou, Ting ; Wang, Qiwei ; Phan, Noel ; Ren, Jun ; Yang, Huan ; Feldman, Conner C ; Feltenberger, John B ; Ye, Zhengqing ; Wildman, Scott A ; Tang, Weiping ; Liu, Bo

Cell death & disease, 2019-03, Vol.10 (3), p.226, Article 226 [Periódico revisado por pares]

England: Springer Nature B.V

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13
MicroRNA-103/107 Regulate Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury Through Targeting FADD
MicroRNA-103/107 Regulate Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury Through Targeting FADD
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MicroRNA-103/107 Regulate Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury Through Targeting FADD

Wang, Jian-Xun ; Zhang, Xiao-Jie ; Li, Qian ; Wang, Kun ; Wang, Yin ; Jiao, Jian-Qin ; Feng, Chang ; Teng, Sun ; Zhou, Lu-Yu ; Gong, Ying ; Zhou, Zhi-Xia ; Liu, Jia ; Wang, Jian-Ling ; Li, Pei-feng

Circulation research, 2015-07, Vol.117 (4), p.352-363 [Periódico revisado por pares]

United States: American Heart Association, Inc

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14
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
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Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

Lupfer, Christopher ; Thomas, Paul G ; Anand, Paras K ; Vogel, Peter ; Milasta, Sandra ; Martinez, Jennifer ; Huang, Gonghua ; Green, Maggie ; Kundu, Mondira ; Chi, Hongbo ; Xavier, Ramnik J ; Green, Douglas R ; Lamkanfi, Mohamed ; Dinarello, Charles A ; Doherty, Peter C ; Kanneganti, Thirumala-Devi

Nature immunology, 2013-05, Vol.14 (5), p.480-488 [Periódico revisado por pares]

United States: Nature Publishing Group

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15
Necroptosis activates UPR sensors without disrupting their binding with GRP78
Necroptosis activates UPR sensors without disrupting their binding with GRP78
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Necroptosis activates UPR sensors without disrupting their binding with GRP78

Liang, Wei ; Qi, Weiwei ; Geng, Yang ; Wang, Linhan ; Zhao, Jing ; Zhu, Kezhou ; Wu, Guowei ; Zhang, Zairong ; Pan, Heling ; Qian, Lihui ; Yuan, Junying

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (39), p.1 [Periódico revisado por pares]

United States: National Academy of Sciences

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16
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
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A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

Nachbur, Ueli ; Stafford, Che A ; Bankovacki, Aleksandra ; Zhan, Yifan ; Lindqvist, Lisa M ; Fiil, Berthe K ; Khakham, Yelena ; Ko, Hyun-Ja ; Sandow, Jarrod J ; Falk, Hendrik ; Holien, Jessica K ; Chau, Diep ; Hildebrand, Joanne ; Vince, James E ; Sharp, Phillip P ; Webb, Andrew I ; Jackman, Katherine A ; Mühlen, Sabrina ; Kennedy, Catherine L ; Lowes, Kym N ; Murphy, James M ; Gyrd-Hansen, Mads ; Parker, Michael W ; Hartland, Elizabeth L ; Lew, Andrew M ; Huang, David C S ; Lessene, Guillaume ; Silke, John

Nature communications, 2015-03, Vol.6 (1), p.6442-6442, Article 6442 [Periódico revisado por pares]

England: Nature Publishing Group

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17
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

Boege, Yannick ; Malehmir, Mohsen ; Healy, Marc E. ; Bettermann, Kira ; Lorentzen, Anna ; Vucur, Mihael ; Ahuja, Akshay K. ; Böhm, Friederike ; Mertens, Joachim C. ; Shimizu, Yutaka ; Frick, Lukas ; Remouchamps, Caroline ; Mutreja, Karun ; Kähne, Thilo ; Sundaravinayagam, Devakumar ; Wolf, Monika J. ; Rehrauer, Hubert ; Koppe, Christiane ; Speicher, Tobias ; Padrissa-Altés, Susagna ; Maire, Renaud ; Schattenberg, Jörn M. ; Jeong, Ju-Seong ; Liu, Lei ; Zwirner, Stefan ; Boger, Regina ; Hüser, Norbert ; Davis, Roger J. ; Müllhaupt, Beat ; Moch, Holger ; Schulze-Bergkamen, Henning ; Clavien, Pierre-Alain ; Werner, Sabine ; Borsig, Lubor ; Luther, Sanjiv A. ; Jost, Philipp J. ; Weinlich, Ricardo ; Unger, Kristian ; Behrens, Axel ; Hillert, Laura ; Dillon, Christopher ; Di Virgilio, Michela ; Wallach, David ; Dejardin, Emmanuel ; Zender, Lars ; Naumann, Michael ; Walczak, Henning ; Green, Douglas R. ; Lopes, Massimo ; Lavrik, Inna ; Luedde, Tom ; Heikenwalder, Mathias ; Weber, Achim

Cancer cell, 2017-09, Vol.32 (3), p.342-359.e10 [Periódico revisado por pares]

United States: Elsevier Inc

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18
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia
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Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

Onorati, Marco ; Li, Zhen ; Liu, Fuchen ; Sousa, André M.M. ; Nakagawa, Naoki ; Li, Mingfeng ; Dell’Anno, Maria Teresa ; Gulden, Forrest O. ; Pochareddy, Sirisha ; Tebbenkamp, Andrew T.N. ; Han, Wenqi ; Pletikos, Mihovil ; Gao, Tianliuyun ; Zhu, Ying ; Bichsel, Candace ; Varela, Luis ; Szigeti-Buck, Klara ; Lisgo, Steven ; Zhang, Yalan ; Testen, Anze ; Gao, Xiao-Bing ; Mlakar, Jernej ; Popovic, Mara ; Flamand, Marie ; Strittmatter, Stephen M. ; Kaczmarek, Leonard K. ; Anton, E.S. ; Horvath, Tamas L. ; Lindenbach, Brett D. ; Sestan, Nenad

Cell reports (Cambridge), 2016-09, Vol.16 (10), p.2576-2592 [Periódico revisado por pares]

United States: Elsevier Inc

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19
Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B
Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B
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Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B

Kelly, Alexander E ; Ghenoiu, Cristina ; Xue, John Z ; Zierhut, Christian ; Kimura, Hiroshi ; Funabiki, Hironori

Science (American Association for the Advancement of Science), 2010-10, Vol.330 (6001), p.235-239 [Periódico revisado por pares]

Washington, DC: American Association for the Advancement of Science

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20
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis
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NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis

Pandey, Amit K ; Yang, Yibin ; Jiang, Zhaozhao ; Fortune, Sarah M ; Coulombe, Francois ; Behr, Marcel A ; Fitzgerald, Katherine A ; Sassetti, Christopher M ; Kelliher, Michelle A Cossart, Pascale

PLoS pathogens, 2009-07, Vol.5 (7), p.e1000500-e1000500 [Periódico revisado por pares]

United States: Public Library of Science

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