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Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling
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Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling

Hrdinka, Matous ; Schlicher, Lisa ; Dai, Bing ; Pinkas, Daniel M ; Bufton, Joshua C ; Picaud, Sarah ; Ward, Jennifer A ; Rogers, Catherine ; Suebsuwong, Chalada ; Nikhar, Sameer ; Cuny, Gregory D ; Huber, Kilian VM ; Filippakopoulos, Panagis ; Bullock, Alex N ; Degterev, Alexei ; Gyrd‐Hansen, Mads

The EMBO journal, 2018-09, Vol.37 (17), p.n/a [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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2
Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models
Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models
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Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models

Zhou, Ting ; Wang, Qiwei ; Phan, Noel ; Ren, Jun ; Yang, Huan ; Feldman, Conner C ; Feltenberger, John B ; Ye, Zhengqing ; Wildman, Scott A ; Tang, Weiping ; Liu, Bo

Cell death & disease, 2019-03, Vol.10 (3), p.226, Article 226 [Periódico revisado por pares]

England: Springer Nature B.V

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3
The Neuroprotective Effects of Necrostatin-1 on Subarachnoid Hemorrhage in Rats Are Possibly Mediated by Preventing Blood–Brain Barrier Disruption and RIP3-Mediated Necroptosis
The Neuroprotective Effects of Necrostatin-1 on Subarachnoid Hemorrhage in Rats Are Possibly Mediated by Preventing Blood–Brain Barrier Disruption and RIP3-Mediated Necroptosis
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The Neuroprotective Effects of Necrostatin-1 on Subarachnoid Hemorrhage in Rats Are Possibly Mediated by Preventing Blood–Brain Barrier Disruption and RIP3-Mediated Necroptosis

Chen, Jingsen ; Jin, Hanghuang ; Xu, Hangzhe ; Peng, Yucong ; Jie, Liyong ; Xu, Demin ; Chen, Lili ; Li, Tao ; Fan, Linfeng ; He, Pingyou ; Ying, Guangyu ; Gu, Chi ; Wang, Chun ; Wang, Lin ; Chen, Gao

Cell transplantation, 2019-11, Vol.28 (11), p.1358-1372 [Periódico revisado por pares]

Los Angeles, CA: SAGE Publications

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4
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
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A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

Nachbur, Ueli ; Stafford, Che A ; Bankovacki, Aleksandra ; Zhan, Yifan ; Lindqvist, Lisa M ; Fiil, Berthe K ; Khakham, Yelena ; Ko, Hyun-Ja ; Sandow, Jarrod J ; Falk, Hendrik ; Holien, Jessica K ; Chau, Diep ; Hildebrand, Joanne ; Vince, James E ; Sharp, Phillip P ; Webb, Andrew I ; Jackman, Katherine A ; Mühlen, Sabrina ; Kennedy, Catherine L ; Lowes, Kym N ; Murphy, James M ; Gyrd-Hansen, Mads ; Parker, Michael W ; Hartland, Elizabeth L ; Lew, Andrew M ; Huang, David C S ; Lessene, Guillaume ; Silke, John

Nature communications, 2015-03, Vol.6 (1), p.6442-6442, Article 6442 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia
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Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia

Onorati, Marco ; Li, Zhen ; Liu, Fuchen ; Sousa, André M.M. ; Nakagawa, Naoki ; Li, Mingfeng ; Dell’Anno, Maria Teresa ; Gulden, Forrest O. ; Pochareddy, Sirisha ; Tebbenkamp, Andrew T.N. ; Han, Wenqi ; Pletikos, Mihovil ; Gao, Tianliuyun ; Zhu, Ying ; Bichsel, Candace ; Varela, Luis ; Szigeti-Buck, Klara ; Lisgo, Steven ; Zhang, Yalan ; Testen, Anze ; Gao, Xiao-Bing ; Mlakar, Jernej ; Popovic, Mara ; Flamand, Marie ; Strittmatter, Stephen M. ; Kaczmarek, Leonard K. ; Anton, E.S. ; Horvath, Tamas L. ; Lindenbach, Brett D. ; Sestan, Nenad

Cell reports (Cambridge), 2016-09, Vol.16 (10), p.2576-2592 [Periódico revisado por pares]

United States: Elsevier Inc

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6
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis
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NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis

Pandey, Amit K ; Yang, Yibin ; Jiang, Zhaozhao ; Fortune, Sarah M ; Coulombe, Francois ; Behr, Marcel A ; Fitzgerald, Katherine A ; Sassetti, Christopher M ; Kelliher, Michelle A Cossart, Pascale

PLoS pathogens, 2009-07, Vol.5 (7), p.e1000500-e1000500 [Periódico revisado por pares]

United States: Public Library of Science

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7
Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2
Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2
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Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2

Trulley, Philipp ; Snieckute, Goda ; Bekker-Jensen, Dorte ; Menon, Manoj B ; Freund, Robert ; Kotlyarov, Alexey ; Olsen, Jesper V ; Diaz-Muñoz, Manuel D ; Turner, Martin ; Bekker-Jensen, Simon ; Gaestel, Matthias ; Tiedje, Christopher

Cell reports (Cambridge), 2019-06, Vol.27 (10), p.2859-2870.e6 [Periódico revisado por pares]

United States: Elsevier Inc

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8
A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells
A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells
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A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells

Lee, Sooncheol ; Micalizzi, Douglas ; Truesdell, Samuel S ; Bukhari, Syed I A ; Boukhali, Myriam ; Lombardi-Story, Jennifer ; Kato, Yasutaka ; Choo, Min-Kyung ; Dey-Guha, Ipsita ; Ji, Fei ; Nicholson, Benjamin T ; Myers, David T ; Lee, Dongjun ; Mazzola, Maria A ; Raheja, Radhika ; Langenbucher, Adam ; Haradhvala, Nicholas J ; Lawrence, Michael S ; Gandhi, Roopali ; Tiedje, Christopher ; Diaz-Muñoz, Manuel D ; Sweetser, David A ; Sadreyev, Ruslan ; Sykes, David ; Haas, Wilhelm ; Haber, Daniel A ; Maheswaran, Shyamala ; Vasudevan, Shobha

Genome Biology, 2020-02, Vol.21 (1), p.33-33, Article 33 [Periódico revisado por pares]

England: BioMed Central Ltd

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9
Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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Promyelocytic leukemia protein targets MK2 to promote cytotoxicity

Chen, I‐Ting ; Chen, Hsiao‐Chi ; Lo, Yu‐Hsun ; Lai, Peng‐Yeh ; Hsieh, Fu‐Yi ; Wu, Yung‐Hsuan ; Shih, Hsiu‐Ming ; Lai, Ming‐Zong

EMBO reports, 2021-12, Vol.22 (12), p.e52254-n/a [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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10
RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions
RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions
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RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions

Estornes, Y ; Aguileta, M A ; Dubuisson, C ; De Keyser, J ; Goossens, V ; Kersse, K ; Samali, A ; Vandenabeele, P ; Bertrand, M J M

Cell death & disease, 2014-12, Vol.5 (12), p.e1555-e1555 [Periódico revisado por pares]

England: Springer Nature B.V

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